6th Workshop in Immunology
Published in 27/9/2018Download file
University of Aveiro, 14 Mar 2018
- Functional link between protein aggregation, inflammation and autophagy in human pDCs allows the development of novel therapies against inflammatory conditions.
- Modulation of immune cells and its interactions with other cell types allows to take advantage of immune responses for novel regenerative therapies.
- Functional intersection between autophagy and TLR signaling in human pDCs function enables development of novel therapies against infections or to treat autoimmune diseases.
- CAL-1 cells are a good cell model for pDC activation with immune complexes.
- The interaction between vMIA and MFF at the peroxisomal membrane is essential for vMIA’s-dependent inhibition of the antiviral immune response.
- Flow cytometry is a complete tool to analyze different parameters at single cell level, are used as biomarkers of disease progression.
- The pro- or anti-inflammatory action of modified amino-phospholipids appears to be related with its molecular species and type of modification.
- Targeting lipid-related pathways is a promising strategy to modulate macrophages phenotype towards enhanced pro-resolving activity.
- Metabolism targeting should modulate macrophage polarization.