Lopes D., Moreira A.S.P., Rey F., da Costa E., Melo T., Maciel E., Rego A., Abreu M.H., Domingues P., Calado R., Lillebo A.I., Domingues M.R. (2019) Lipidomic signature of the green macroalgae Ulva rigida farmed in a sustainable integrated multi-trophic aquaculture.
JOURNAL OF APPLIED PHYCOLOGY, 31
, (2), 1369-1381.
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Lopes C., Barbosa J., Maciel E., da Costa E., Alves E., Domingues P., Mendo S., Domingues M.R.M. (2019) Lipidomic signature of Bacillus licheniformis 189 during the different growth phases unravelled by high-resolution liquid chromatography-mass spectrometry.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 663
83-94.
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Maciel E., Lillebo A., Domingues P., da Costa E., Calado R., Domingues M.R.M. (2018) Polar lipidome profiling of Salicornia ramosissima and Halimione portulacoides and the relevance of lipidomics for the valorization of halophytes.
PHYTOCHEMISTRY, 153
94-101.
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Araujo A.R.D., Melo T., Maciel E.A., Pereira C., Morais C.M., Santinha D.R., Tavares J.F., Oliveira H., Jurado A.S., Costa V., Domingues P., Domingues M.R.M., Santos M.A.S. (2018) Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast.
PLOS ONE, 13
, (8), .
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Moreira A.S.P., Nunes F.M., Simoes C., Maciel E., Domingues P., Domingues M.R.M., Coimbra M.A. (2017) Transglycosylation reactions, a main mechanism of phenolics incorporation in coffee melanoidins: Inhibition by Maillard reaction.
FOOD CHEMISTRY, 227
422-431.
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Felix L., Oliveira M.M., Videira R., Maciel E., Alves N.D., Nunes F.M., Alves A., Almeida J.M., Domingues M.R.M., Peixoto F.P. (2017) Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat.
EXPERIMENTAL AND TOXICOLOGIC PATHOLOGY, 69
, (2), 83-92.
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Maciel E., Felgueiras J., Silva E.M.P., Ricardo F., Moreira A.S.P., Melo T., Campos A., Fardilha M., Domingues P., Domingues M.R. (2017) Lipid remodelling in human melanoma cells in response to UVA exposure.
PHOTOCHEMICAL & PHOTOBIOLOGICAL SCIENCES, 16
, (5), 744-752.
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Rocha-Rodrigues S., Rodriguez A., Goncalves I.O., Moreira A., Maciel E., Santos S., Domingues M.R., Fruhbeck G., Ascensao A., Magalhaes J. (2017) Impact of physical exercise on visceral adipose tissue fatty acid profile and inflammation in response to a high-fat diet regimen.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 87
114-124.
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Ricardo F., Maciel E., Domingues R., Calado R. (2017) Spatio-temporal variability in the fatty acid profile of the adductor muscle of the common cockle Cerastoderma edule and its relevance for tracing geographic origin.
FOOD CONTROL, 81
173-180.
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Ricardo F., Pimentel T., Maciel E., Moreira A.S.P., Domingues M.R., Calado R. (2017) Fatty acid dynamics of the adductor muscle of live cockles (Cerastoderma edule) during their shelf-life and its relevance for traceability of geographic origin.
FOOD CONTROL, 77
192-198.
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Martins J.D., Maciel E.A., Silva A., Ferreira I., Ricardo F., Domingues P., Neves B.M., Domingues M.R.M., Cruz M.T. (2016) Phospholipidomic Profile Variation on THP-1 Cells Exposed to Skin or Respiratory Sensitizers and Respiratory Irriant.
JOURNAL OF CELLULAR PHYSIOLOGY, 231
, (12), 2639-2651.
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Magalhaes-Novais S., Loureiro R., Mesquita K.A., Baldeiras I., Domingues M.R., Maciel E., Oliveira P.J., Vega-Naredo I. (2016) P19 embryonic carcinoma cell differentiation induces alterations in mitochondrial redox homeostasis and cell death.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 46
65-66.
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Campos A.M., Maciel E., Moreira A.S.P., Sousa B., Melo T., Domingues P., Curado L., Antunes B., Domingues M.R.M., Santos F. (2016) Lipidomics of Mesenchymal Stromal Cells: Understanding the Adaptation of Phospholipid Profile in Response to Pro-Inflammatory Cytokines.
JOURNAL OF CELLULAR PHYSIOLOGY, 231
, (5), 1024-1032.
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Sousa B., Melo T., Campos A., Moreira A.S.P., Maciel E., Domingues P., Carvalho R.P., Rodrigues T.R., Girao H., Domingues M.R.M. (2016) Alteration in Phospholipidome Profile of Myoblast H9c2 Cell Line in a Model of Myocardium Starvation and Ischemia.
JOURNAL OF CELLULAR PHYSIOLOGY, 231
, (10), 2266-2274.
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Couto D., Melo T., Maciel E., Campos A., Alves E., Guedes S., Domingues M.R.M., Domingues P. (2016) New Insights on Non-Enzymatic Oxidation of Ganglioside GM1 Using Mass Spectrometry.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 27
, (12), 1965-1978.
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Maciel E., Leal M.C., Lillebo A.I., Domingues P., Domingues M.R., Calado R. (2016) Bioprospecting of Marine Macrophytes Using MS-Based Lipidomics as a New Approach.
MARINE DRUGS, 14
, (3), .
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Tyurina Y.Y., Polimova A.M., Maciel E., Tyurin V.A., Kapralova V.I., Winnica D.E., Vikulina A.S., Domingues M.R.M., McCoy J., Sanders L.H., Bayir H., Greenamyre J.T., Kagan V.E. (2015) LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease.
FREE RADICAL RESEARCH, 49
, (5), 681-691.
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Martins J., Maciel E.A., Silva A., Domingues P., Neves B.M., Cruz M.T., Domingues M.R. (2015) Phospholipidomic profile variation on dendritic-like cells exposed to skin or respiratory sensitizers and respiratory irritant.
TOXICOLOGY LETTERS, 238
, (2), S235-S236.
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Novais S.M., Domingues M.R., Maciel E., Melo T., Vega-Naredo I., Oliveira P.J. (2015) Cardiolipin synthesis and modifications during P19 embryonic carcinoma cell differentiation.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 45
54-54.
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Goncalves I.O., Maciel E., Passos E., Torrella J.R., Rizo D., Viscor G., Rocha-Rodrigues S., Santos-Alves E., Domingues M.R., Oliveira P.J., Ascensao A., Magalhaes J. (2014) Exercise alters liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitis.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY, 54
163-173.
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Santinha D., Ferreira-Fernandes E., Melo T., Silva E.M.P., Maciel E., Fardilha M., Domingues P., Domingues M.R.M. (2014) Evaluation of the photooxidation of galactosyl- and lactosylceramide by electrospray ionization mass spectrometry.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 28
, (21), 2275-2284.
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Lourenco L.M.O., Pereira P.M.R., Maciel E., Valega M., Domingues F.M.J., Domingues M.R.M., Neves M.G.P.M.S., Cavaleiro J.A.S., Fernandes R., Tome J.P.C. (2014) Amphiphilic phthalocyanine-cyclodextrin conjugates for cancer photodynamic therapy.
CHEMICAL COMMUNICATIONS, 50
, (61), 8363-8366.
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Antunes D., Padrao A.I., Maciel E., Santinha D., Oliveira P., Vitorino R., Moreira-Goncalves D., Colaco B., Pires M.J., Nunes C., Santos L.L., Amado F., Duarte J.A., Domingues M.R., Ferreira R. (2014) Molecular insights into mitochondrial dysfunction in cancer-related muscle wasting.
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR AND CELL BIOLOGY OF LIPIDS, 1841
, (6), 896-905.
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Maciel E., Neves B.M., Santinha D., Reis A., Domingues P., Cruz M.T., Pitt A.R., Spickett C.M., Domingues M.R.M. (2014) Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 548
38-45.
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Tyurina Y.Y., Domingues R.M., Tyurin V.A., Maciel E., Domingues P., Amoscato A.A., Bayir H., Kagan V.E. (2014) Characterization of cardiolipins and their oxidation products by LC-MS analysis.
CHEMISTRY AND PHYSICS OF LIPIDS, 179
3-10.
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Goncalves I.O., Maciel E., Passos E., Torrella J.R., Rizo D., Viscor G., Rocha-Rodrigues S., Santos-Alves E., Domingues M.R., Oliveira P.J., Ascensao A., Magalhaes J. (2014) Exercise improves liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitis.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 44
56-56.
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Pinto J., Maciel E., Melo T.S., Domingues M.R.M., Galhano E., Pita C., Almeida M.D., Carreira I.M., Gil A.M. (2014) Maternal plasma phospholipids are altered in trisomy 21 cases and prior to preeclampsia and preterm outcomes.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 28
, (14), 1635-1638.
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Faria R., Santana M.M., Aveleira C.A., Simoes C., Maciel E., Melo T., Santinha D., Oliveira M.M., Peixoto F., Domingues P., Cavadas C., Domingues M.R.M. (2014) ALTERATIONS IN PHOSPHOLIPIDOMIC PROFILE IN THE BRAIN OF MOUSE MODEL OF DEPRESSION INDUCED BY CHRONIC UNPREDICTABLE STRESS.
NEUROSCIENCE, 273
1-11.
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Melo T., Santos N., Lopes D., Alves E., Maciel E., Faustino M.A.F., Tome J.P.C., Neves M.G.P.M.S., Almeida A., Domingues P., Segundo M.A., Domingues M.R.M. (2013) Photosensitized oxidation of phosphatidylethanolamines monitored by electrospray tandem mass spectrometry.
JOURNAL OF MASS SPECTROMETRY, 48
, (12), 1357-1365.
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Monteiro J.P., Pereira C.V., Silva A.M., Maciel E., Baldeiras I., Peixoto F., Domingues M.R., Jurado A.S., Oliveira P.J. (2013) Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics.
ARCHIVES OF TOXICOLOGY, 87
, (12), 2151-2163.
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Maciel E., Faria R., Santinha D., Domingues M.R.M., Domingues P. (2013) Evaluation of oxidation and glyco-oxidation of 1-palmitoyl-2-arachidonoyl-phosphatidylserine by LC-MS/MS.
JOURNAL OF CHROMATOGRAPHY B-ANALYTICAL TECHNOLOGIES IN THE BIOMEDICAL AND LIFE SCIENCES, 929
76-83.
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Santinha D.R., Doria M.L., Neves B.M., Maciel E.A., Martins J., Helguero L., Domingues P., Cruz M.T., Domingues M.R. (2013) Prospective phospholipid markers for skin sensitization prediction in keratinocytes: A phospholipidomic approach.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 533
, (1-2), 33-41.
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Alves E., Santos N., Melo T., Maciel E., Doria M.L., Faustino M.A.F., Tome J.P.C., Neves M.G.P.M.S., Cavaleiro J.A.S., Cunha A., Helguero L.A., Domingues P., Almeida A., Domingues M.R.M. (2013) Photodynamic oxidation of Escherichia coli membrane phospholipids: new insights based on lipidomics.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 27
, (23), 2717-2728.
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Maciel E., da Silva R.N., Simoes C., Melo T., Ferreira R., Domingues P., Domingues M.R.M. (2013) Liquid chromatography-tandem mass spectrometry of phosphatidylserine advanced glycated end products.
CHEMISTRY AND PHYSICS OF LIPIDS, 174
1-7.
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da Silva R.N., Silva A.C., Maciel E., Simoes C., Horta S., Laranjeira P., Paiva A., Domingues P., Domingues M.R.M. (2012) Evaluation of the capacity of oxidized phosphatidylserines to induce the expression of cytokines in monocytes and dendritic cells.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 525
, (1), 9-15.
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Villaverde J.J., Santos S.A.O., Maciel E., Simoes M.M.Q., Neto C.P., Domingues M.R.M., Silvestre A.J.D. (2012) Formation of oligomeric alkenylperoxides during the oxidation of unsaturated fatty acids: an electrospray ionization tandem mass spectrometry study.
JOURNAL OF MASS SPECTROMETRY, 47
, (2), 163-172.
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Santinha D.R., Marques D.R., Maciel E.A., Simoes C.S.O., Rosa S., Neves B.M., Macedo B., Domingues P., Cruz M.T., Domingues M.R.M. (2012) Profiling changes triggered during maturation of dendritic cells: a lipidomic approach.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 403
, (2), 457-471.
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Monteiro J.P., Pereira C., Maciel E., Baldeiras I., Peixoto F., Domingues M.R., Jurado A.S., Oliveira P.J. (2012) Rapeseed oil-based diet alters rat hepatic mitochondria physiology and membrane composition.
EUROPEAN JOURNAL OF CLINICAL INVESTIGATION, 42
74-74.
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Melo T., Maciel E., Oliveira M.M., Domingues P., Domingues M.R.M. (2012) Study of sphingolipids oxidation by ESI tandem MS.
EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 114
, (7), 726-732.
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Melo T., Videira R.A., Andre S., Maciel E., Francisco C.S., Oliveira-Campos A.M., Rodrigues L.M., Domingues M.R.M., Peixoto F., Oliveira M.M. (2012) Tacrine and its analogues impair mitochondrial function and bioenergetics: a lipidomic analysis in rat brain.
JOURNAL OF NEUROCHEMISTRY, 120
, (6), 998-1013.
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Maciel E., da Silva R.N., Simoes C., Domingues P., Domingues M.R.M. (2011) Structural Characterization of Oxidized Glycerophosphatidylserine: Evidence of Polar Head Oxidation.
JOURNAL OF THE AMERICAN SOCIETY FOR MASS SPECTROMETRY, 22
, (10), 1804-1814.
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Maciel E., Domingues P., Marques D., Simoes C., Reis A., Oliveira M.M., Videira R.A., Peixoto F., Domingues M.R.M. (2011) Cardiolipin and oxidative stress: Identification of new short chain oxidation products of cardiolipin in in vitro analysis and in nephrotoxic drug-induced disturbances in rat kidney tissue.
INTERNATIONAL JOURNAL OF MASS SPECTROMETRY, 301
, (1-3), 62-73.
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Reis A., Fonseca C., Maciel E., Domingues P., Domingues M.R.M. (2011) Influence of amino acid relative position on the oxidative modification of histidine and glycine peptides.
ANALYTICAL AND BIOANALYTICAL CHEMISTRY, 399
, (8), 2779-2794.
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Maciel E., Domingues P., Domingues M.R.M. (2011) Liquid chromatography/tandem mass spectrometry analysis of long-chain oxidation products of cardiolipin induced by the hydroxyl radical.
RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 25
, (2), 316-326.
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Monteiro J.P., Pereira C., Maciel E., Baldeiras I., Peixoto F., Domingues M.R., Jurado A.S., Oliveira P.J. (2011) The Influence of Diet in Rat Hepatic Mitochondria Physiology and Membrane Composition: Rapeseed Oil As a Case Study.
JOURNAL OF GENERAL PHYSIOLOGY, 138
, (1), 22A-22A.
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Maria Elisabete Alves Maciel
Auxiliary Researcher
- Researcher ID: I-8868-2017
- ORCID: 0000-0003-3637-6854
- Department: Biology
- Research Group: Marine Biotechnology & Aquaculture
- ISI Web of KnowledgeSM search factor: AU=(Maciel E) AND AD= (Aveiro); AUTHOR IDENTIFIERS: (0000-0003-3637-6854)
Research interests
Marine Lipidomics: Lipid signature of marine organisms (bivalves, fish and macrophytes)
Plant Lipidomics: bioprospection and valorization of halophyte plants
Lipids as a biologically active compounds
Lipidomics under oxidative stress conditions: Study of the structural modifications of lipids
Plant Lipidomics: bioprospection and valorization of halophyte plants
Lipids as a biologically active compounds
Lipidomics under oxidative stress conditions: Study of the structural modifications of lipids
Academic degrees
2014 - PhD in Biochemistry, University of Aveiro, Portugal
2010 - MSc in Biomolecular Methods, University of Aveiro, Portugal
2008 - First degree in Biochemistry, University of Aveiro, Portugal
2010 - MSc in Biomolecular Methods, University of Aveiro, Portugal
2008 - First degree in Biochemistry, University of Aveiro, Portugal
Scientific activities
May 2018 – Present: Assistant Researcher contracted under Project SmartBioR - Smart Valorization of Biological Marine Resources (Centro 2020)
Feb 2015 – Apr 2018: Post-doctoral researcher at the Department of Biology & CESAM and Department of Chemistry & QOPNA, University of Aveiro, Portugal.
Mar 2011 - Dec 2014: PhD student at the Department of Chemistry & QOPNA, University of Aveiro, Portugal
Feb 2015 – Apr 2018: Post-doctoral researcher at the Department of Biology & CESAM and Department of Chemistry & QOPNA, University of Aveiro, Portugal.
Mar 2011 - Dec 2014: PhD student at the Department of Chemistry & QOPNA, University of Aveiro, Portugal
Others
Guest Editor of the special issue ‘Lipid Profiling (Lipidome) of Marine Organisms’ in the open access journal Marine Drugs
Aug 2018 - Present: Member of EuroMarine working group for research infrastructures (RIs)
Taught short course:
• Practical courses on mass spectrometry - From the basics to LC-MS data acquisition and interpretation (1st, 2nd,3rd and 4th edition)
• Practical Courses on Mass Spectrometry -Advanced Course in Lipidomics (1st edition)
Aug 2018 - Present: Member of EuroMarine working group for research infrastructures (RIs)
Taught short course:
• Practical courses on mass spectrometry - From the basics to LC-MS data acquisition and interpretation (1st, 2nd,3rd and 4th edition)
• Practical Courses on Mass Spectrometry -Advanced Course in Lipidomics (1st edition)
Publications
WoS Papers
(45)
Other Papers
(4)
Books
(0)
Book Chapter
(1)
Thesis
(2)
Communications
(12)
Other Publications
(0)
Reports
(0)
Projects
In Progress (4)
Concluded (2)
Omics4Algae - Lipidomic tools for chemical phenotyping, traceability and valorisation of seaweeds from aquaculture as a sustainable source of high added-value compounds
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SUShI - SUStainable use of Insect protein in aquaculture feed
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TraSeafood - Tracing the Geographic Origin of Seafood as a Pathway Towards the Smart Valorization of Endogenous Marine Resources
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SmartBioR - Smart Valorization of Biological Marine Resources.
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Scientific Supervision
In progress
(1)
Concluded
(3)
Master (Co-supervisor):
Pedro Martins Duarte
(not a CESAM member)
Master (Main Supervisor):
Rui Pedro de Melo Silva
(not a CESAM member)
BSc students (Co-supervisor):
Alicia Rodrigues Antunes
(not a CESAM member)
BSc students (Co-supervisor):
Vitor Azevedo
(not a CESAM member)
Participation in R&D projects
2015-2017- Member of the research team of “Advanced Analytical Chemistry for Life Sciences” (ACCLifeSci) (ERASMUS+), Universidade de Białystok, Polónia.
Member of the research team of the funded project: the role of aminophospholipid glycosylation in oxidative stress and their immune response: a lipidomic approach (PTDC/QUIBIQ/104968/2008)
Prizes and awards received
2016 – Best communication - Elisabete Maciel, Ricardo Calado, Ana Lillebø, Daniel Ettilinc, Pedro Domingues and Rosário Domingues. Valorization of autochthonous halophyte plants through hydrophilic interaction chromatography coupled to Q Exactive mass spectrometer received the award for the best Communication in LC-MS at the international conference XVI COLACRO- Latin-American Congress on Cromatography
CESAM Funding:
CESAM © 2019 | All rights reserved.