Building the future by doing more together

Maternal-fetal transfer of mercury in women from Aveiro district: influence of lifestyle and environmental factors
Coordinator - Marta Monteiro
Programme - - Observatoire Hommes-Millieux - Estarreja
Execution dates - 2015-06-01 - 2016-05-31 (12 Months)
Funding Entity - CNRS/INEE - National Centre for Scientific Research/Institute of Ecology and Environment, via OHMI – International Observatory Hommes-Millieux
Funding for CESAM - 6000 €
Total Funding - 6000 €
Proponent Institution - Universidade de Aveiro

This project aims at assessing the accumulation of Hg by woman living in the Aveiro district, and
the potential maternal-fetal transfer during pregnancy. In addition to Hg measurements, related
oxidative stress, neurotoxicity and DNA damage effects will also be evaluated in both mother
and baby tissues and blood. Although some epidemiological studies have already related Hg
accumulation in several matrices regarding maternal-fetal transfer, only few studies have
regarded this approach in Portugal, and none for the Aveiro district (which includes Estarreja). In
addition, only few epidemiological studies have focused on genotoxicity to evaluate Hg exposure in humans.
Therefore integrating biomarkers of exposure (Hg measures in maternal and fetal matrices)
along with biomarkers of effects (e.g. oxidative stress and DNA damage) will improve the
knowledge on the historical problem of Hg contamination in Estarreja and in the Aveiro district,
along with the potential action from local authorities if results show concern to human health.

Members on this project
Marta S. Monteiro
Susana Loureiro

CESAM Funding: