Elisabete Valente da Costa
Post-Doctoral Research Fellow
- Researcher ID: N-3254-2018
- ORCID: 0000-0003-0309-5132
- Departamento: Química
- Grupo de Investigação: Biotecnologia Marinha e Aquacultura
- ISI Web of KnowledgeSM search factor: AU=da Costa E AND AD=Aveiro Título: GENIALG – Genetic diversity exploitation for innovative macro-alga biorefinery Orientador: Dr. Ricardo Calado Category: BO Grant type: BPD Funding entity: GENIALG (ANR-15-MRSE-0015) funded by European Union’s Horizon 2020 Framework Programme Grant reference: BPD/ UI51/5042/2018 Start date: 2018-04-01 End date: 2020-03-31
Interesses de investigação
ﷻEvaluation of biological activities of algae lipids for new therapeutics products;
ﷻEco-friendly strategies for the extraction of bioactive added value lipids;
ﷻ Valorisation of biomass following a Biorefinery concept: in the pursuit of lipids, polysaccharides, proteins, pigments, and minerals for specific uses in the medical, pharmaceutical, biotech, food or feed industry...
01/2008 – Master in Instrumental Methods and Analytical Quality Control:Study of ellagic acid profile in the kraft process of pulp from Eucalyptus globulus
2000 - First Degree in Industrial Chemistry, Processes and industrial synthesis: Study of the electroreduction reaction of hydrogen peroxide in alkaline solution on a surface of polycrystalline gold
2010/2013 - Research grant and member: FCT/ QOPNA/ UA: PTDC/QUI-QUI/100044/2008
2004/2007 - Researcher at RAIZ, Instituto de Investigação da Floresta e do Papel (The Navigator Company).
2003/2004 - Head of laboratory and quality control of accredited laboratory (EN17025) at RAIZ, Instituto de Investigação da Floresta e do Papel (The Navigator Company)
2002/2004 - Trainee researcher at RAIZ, Instituto de Investigação da Floresta e do Papel (The Navigator Company)
2000/2002 - Trainee as laboratory technician, Portucel Cacia gPS (The Navigator Company)
2019 - Honourable mention in the Biochemistry Day, Poster Awards, 15th May 2019
2017 - Award for the best 3rd cycle degree student of the Chemistry Department,9th June. Universidade de Aveiro, Portugal.
2017 - Second best showcase, Biorefinery and valorization of macroalgae,Conference of Materiais, 9-12th April. Universidade de Aveiro, Portugal.
2016 - Best oral communication: High added value products from macroalgae. First scientific meeting of the Doctoral Programme in Sustainable Chemistry, 26th September. Universidade de Aveiro, Portugal.
2013 - Best Poster Award: Hydroxyl radical-induced oxidation of arabinotriose, a model of coffee arabinogalactan side chains. Award attributed during the 2nd International Congress on Cocoa Coffee and Tea. Napoles, Italy (M. Domingues, A. Moreira, E. Costa, D. Evtyugin, F. Nunes and M. Coimbra)
Organization committee of scientific events and conferences
Organization and trainer in practical specialization advances courses in Lipidomics and Glycomics
Referee/issued opinions on scientific articles for international journals
1 - Molecules
2 - Algal Research
3 - Grasas e Aceites
2010-2013 FCT/ QOPNA/UA:PTDC/QUI-QUI/100044/2008 (Concluded)
Researcher and member
Study of structural modifications induced by thermal and oxidative degradation in oligo and polysaccharides by advanced mass spectrometry
From zebrafish to meagre: use of macro- and microalgae as functional feed
Partners: Faculdade de Ciências da Universidade do Porto, REQUIMTE, Departamento de Química da
Universidade de Aveiro, CIIMAR.
Lopes C., Barbosa J., Maciel E., da Costa E., Alves E., Ricardo F., Domingues P., Mendo S., Domingues M.R.M. (2019) Decoding the Fatty Acid Profile of Bacillus licheniformis I89 and Its Adaptation to Different Growth Conditions to Investigate Possible Biotechnological Applications. LIPIDS, 54 , (4), 245-253. Ver mais
Lopes C., Barbosa J., Maciel E., da Costa E., Alves E., Domingues P., Mendo S., Domingues M.R.M. (2019) Lipidomic signature of Bacillus licheniformis 189 during the different growth phases unravelled by high-resolution liquid chromatography-mass spectrometry. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 663 83-94. Ver mais
da Costa E., Domingues P., Melo T., Coelho E., Pereira R., Calado R., Abreu M.H., Domingues M.R. (2019) Lipidomic Signatures Reveal Seasonal Shifts on the Relative Abundance of High-Valued Lipids from the Brown Algae Fucus vesiculosus. MARINE DRUGS, 17 , (6), . Ver mais
Alves E., Rey F., da Costa E., Moreira A.S.P., Pato L., Pato L., Domingues M.D.M., Domingues P. (2018) Olive (Olea europaea L. cv. Galega vulgar) Seed Oil: A First Insight into the Major Lipid Composition of a Promising Agro-Industrial By-Product at Two Ripeness Stages. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY, 120 , (4), . Ver mais
Maciel E., Lillebo A., Domingues P., da Costa E., Calado R., Domingues M.R.M. (2018) Polar lipidome profiling of Salicornia ramosissima and Halimione portulacoides and the relevance of lipidomics for the valorization of halophytes. PHYTOCHEMISTRY, 153 94-101. Ver mais
da Costa E., Azevedo V., Melo T., Rego A.M., Evtuguin D.V., Domingues P., Calado R., Pereira R., Abreu M.H., Domingues M.R. (2018) High-Resolution Lipidomics of the Early Life Stages of the Red Seaweed Porphyra dioica. MOLECULES, 23 , (1), . Ver mais
Rey F., da Costa E., Campos A.M., Cartaxana P., Maciel E., Domingues P., Domingues M.R.M., Calado R., Cruz S. (2017) Kleptoplasty does not promote major shifts in the lipidome of macroalgal chloroplasts sequestered by the sacoglossan sea slug Elysia viridis. SCIENTIFIC REPORTS, 7 . Ver mais
da Costa E., Melo T., Moreira A.S.P., Bernardo C., Helguero L., Ferreira I., Cruz M.T., Rego A.M., Domingues P., Calado R., Abreu M.H., Domingues M.R. (2017) Valorization of Lipids from Gracilaria sp through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity. MARINE DRUGS, 15 , (3), . Ver mais
da Costa E., Silva J., Mendonca S.H., Abreu M.H., Domingues M.R. (2016) Lipidomic Approaches towards Deciphering Glycolipids from Microalgae as a Reservoir of Bioactive Lipids. MARINE DRUGS, 14 , (5), . Ver mais
Simoes J., Moreira A.S.P., da Costa E., Evtyugin D., Domingues P., Nunes F.M., Coimbra M.A., Domingues R.M. (2016) Oxidation of amylose and amylopectin by hydroxyl radicals assessed by electrospray ionisation mass spectrometry. CARBOHYDRATE POLYMERS, 148 290-299. Ver mais
da Costa E., Melo T., Moreira A.S.P., Alves E., Domingues P., Calado R., Abreu M.H., Domingues M.R. (2015) Decoding bioactive polar lipid profile of the macroalgae Codium tomentosum from a sustainable IMTA system using a lipidomic approach. ALGAL RESEARCH-BIOMASS BIOFUELS AND BIOPRODUCTS, 12 388-397. Ver mais
Costa E.V., Lima D.L.D., Evtyugin D.V., Esteves V.I. (2014) Development and application of a capillary electrophoresis method for the determination of ellagic acid in E. globulus wood and in filtrates from E. globulus kraft pulp. Wood Science And Technology, 48 , (1), 99-108. Ver mais
Moreira A.S.P., da Costa E.V., Evtuguin D.V., Coimbra M.A., Nunes F.M., Domingues M.R.M. (2014) Neutral and acidic products derived from hydroxyl radical-induced oxidation of arabinotriose assessed by electrospray ionisation mass spectrometry. JOURNAL OF MASS SPECTROMETRY, 49 , (4), 280-290. Ver mais
da Costa E.V., Moreira A.S.P., Nunes F.M., Coimbra M.A., Evtuguin D.V., Domingues M.R.M. (2012) Differentiation of isomeric pentose disaccharides by electrospray ionization tandem mass spectrometry and discriminant analysis. RAPID COMMUNICATIONS IN MASS SPECTROMETRY, 26 , (24), 2897-2904. Ver mais
Ershova O., da Costa E.V., Fernandes A.J.S., Domingues M.R., Evtuguin D.V., Sixta H. (2012) Effect of urea on cellulose degradation under conditions of alkaline pulping. CELLULOSE, 19 , (6), 2195-2204. Ver mais
Prozil S.O., Costa E.V., Evtuguin D.V., Lopes L.P.C., Domingues M.R.M. (2012) Structural characterization of polysaccharides isolated from grape stalks of Vitis vinifera L. CARBOHYDRATE RESEARCH, 356 252-259. Ver mais
Elisabete V. da Costa, Ana S. P. Moreira, Maria R. Domingues, Dmitry V. Evtuguin First Workshop of mass spectrometry analysis of carbohydrates. 18th April 2012. Universidade De Aveiro, Portugal, . Ver mais
Elisabete da Costa Potential application of Gracilaria spp. and Ulva spp. in food and cosmetics. Closing Of Projects CIGArRA E ALGADOURADA, 10th December 2015. CIEMAR, Ílhavo, Portugal, . Ver mais
The effects of different extraction methods of lipids from Nannochloropsis oceanica on the contents of omega-3 fatty acids Article. . Ver mais
Lipidomics Reveals Similar Changes in Serum Phospholipid Signatures of Overweight and Obese Pediatric Subjects. . Ver mais
Elisabete Valente da Costa (2008) Study of ellagic acid profile in the kraft process of pulp from Eucalyptus globulus. MSc Thesis. . Ver mais
Elisabete Valente da Costa (2000) Study of the electroreduction reaction of hydrogen peroxide in alkaline solution on a surface of polycrystalline gold. . Ver mais
Rey F, da Costa E, Campos AM, Cartaxana P, Maciel E, Domingues P, Domingues MRM, Calado R, Cruz S (2018) Chloroplasts sequestered by the sacoglossan sea slug Elysia viridis preserve original lipidome of plastid membranes. 31st Congress New European Society for Compartive Physiology and Biochemistry, 9-12th September 2018, Porto, Portugal . Ver mais
Rey F, da Costa E, Campos AM, Cartaxana P, Maciel E, Domingues P, Domingues MRM, Calado R, Cruz S (2018) Gas phase fragmentation confirms plastidial glycolipids in photosynthetic animals. 9th Meeting of the Analytical Chemistry Division, 26-27 th March 2018, Porto, Portugal . Ver mais
Elisabete V. da Costa, Ana S. P. Moreira, Maria R. Domingues, Dmitry V. Evtuguin Oxidation of xylooligosaccharide models by chlorine dioxide, . , , . Ver mais
Elisabete V. da Costa, Ana S. P. Moreira, Maria R. Domingues, Dmitry V. Evtuguin Understanding bleaching process during pulp and paper industrial process. , , . Ver mais
Elisabete V. da Costa, Ana S. P. Moreira, Maria R. Domingues, Dmitry V. Evtuguin Mass spectrometry assessment of xylo-oligosaccharides oxidation by hydroxyl radicals: understanding pulp bleaching degradation of xylans. , , . Ver mais
Elisabete V. da Costa, Ana S. P. Moreira, Maria R. Domingues, Dmitry V. Evtuguin Formation of chromogenic structures from xylan by chlorine dioxide as revealed from model experiments. , , . Ver mais
Elisabete da Costa, Rosário Domingues Bioprospection of glycolipids from macroalgae using mass spectrometry - based approaches. , , . Ver mais
Elisabete da Costa, Andreia Rego, Helena Abreu, Rosário Domingues Deciphering the lipidome of the seaweed Gracilaria sp. from a land-based IMTA system in the lagoon of Aveiro. , , . Ver mais
Patrícia Diaz Rosales, Catarina Guedes, Helena Peres, Isabel Azevedo, Elisabete da Costa, Rosário Domingues, Isabel Sousa-Pinto et al From zebrafish to meagre: use of macroalgae as functional feeds. , , . Ver mais
Elisabete da Costa, Tânia Melo, Ana S.P. Moreira, Eliana Alves, Pedro Domingues, Ricardo Calado, Maria H. Abreu, Maria Rosário Domingues Deciphering the lipidomic profile of the seaweed Codium tomentosum toward the bioprospection of bioactive phytochemicals. , , . Ver mais
Elisabete Da Costa, Tânia Melo, Elisabete Maciel, Ana Lillebø, Ricardo Calado, Pedro Domigues, Helena Abreu, Rosário Domingues How to use lipidomic tools in red and green seaweeds signature and bioprospection? Codium tomentosum and Gracilaria sp. as showcases. , , . Ver mais
Elisabete da Costa Potential application of Gracilaria spp. and Ulva spp. in food and cosmetics. , , . Ver mais
Da Costa E., Melo T., Rego A.R., Moreira A.S.P., Lopes D. , Domingues P. , Pereira R. , Abreu M.H. , Calado R. , Domingues M.R. Seaweeds lipids in health-promotion: Lipidomics holding with lipid diversity, Lipids in the Ocean, 20-22 November 2018, Brest, France . Lipids in the Ocean, 20-22 November 2018 , Brest, France. Ver mais
Current research interests
- Lipidomic studies of macroalgae by using chromatographic and mass spectrometry approaches: taxonomic variation and environmental and/or physiological response of lipids;
- Evaluation of the biological functionality of algae lipids in therapeutic and nutraceutical;
- New friendly methodologies in the extraction of bioactive compounds;
- Composition of macroalgae (polysaccharides, proteins, pigments, and minerals) and biorefinery concept fostering the integral or fractionated valorization of biomass.
Elisabete da Costa has graduated in Industrial Chemistry in the University of Coimbra and received her MSc in Instrumental Methods and Analytical Control, at the University of Aveiro, in 2008. Following the industrial career at Grupo PortucelSoporcel, she started her scientific career in 2010 at the University of Aveiro (CICECO/QOPNA/Centre of Mass Spectrometry), received her Ph.D. in Sustainable Chemistry entitled High added value products from macroalgae: lipids as bioactive compounds at the University of Aveiro and ALGAPlus company, in 2018. She is pursuing a research PosDoc of the project GENIALG – Genetic diversity exploitation for innovative macro-alga biorefinery (ANR-15-MRSE-0015) funded by European Union’s Horizon 2020 Framework Programme.
She published thirteen original papers, delivered ten invited oral communications, ten poster communications in several national and international scientific meetings and has been member and researcher in national projects and several workshops promoting Mass Spectrometry, Chemistry and the Valorisation of Macroalgae as a sustainable resource. She has won 4 prizes, was scientific adviser of 1 B.Sc. and 2 M.Sc. students, was referee of 3 papers from international journals and has experience in the execution and planning of research projects.
CESAM © 2019 | Todos os direitos reservados.