Pereira V., Marques A., Gaivao I., Rego A., Abreu H., Pereira R., Santos M.A., Guilherme S., Pacheco M. (2019) Marine macroalgae as a dietary source of genoprotection in gilthead seabream (Sparus aurata) against endogenous and exogenous challenges.
Comparative Biochemistry And Physiology C - Toxicology & Pharmacology, 219
12-24.
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A. Marques, R. Marçal, V. Pereira, P. Pereira , C. Mieiro,S. Guilherme, C. Marques, M.A. D. M. Santos, R. Pereira, M.H. Abreu,I. Gaivão, M. Pacheco (2019) Macroalgae-enriched diet protects gilthead seabream (Sparus aurata) against erythrocyte population instability and chromosomal damage induced by aqua-medicines.
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1-17.
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Guilherme S., Crespo R., Azevedo D., Marques A., Santos M.A., Serradeiro R., Pacheco M. (2019) DNA and chromosomal damage in Senegalese sole (Solea senegalensis) as side effects of ozone-based water treatment - Contribution to optimization of fish-farming practices.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 219
68-76.
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Pereira R., Leite E., Raimundo J., Guilherme S., Puga S., Pinto-Ribeiro F., Santos M.A., Canario J., Almeida A., Pacheco M., Pereira P. (2018) Metals(loids) targeting fish eyes and brain in a contaminated estuary - Uncovering neurosensory (un)susceptibility through bioaccumulation, antioxidant and morphometric profiles.
MARINE ENVIRONMENTAL RESEARCH, 140
403-411.
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Maria V.L., Ribeiro M.J., Guilherme S., Soares A.M.V.M., Scott-Fordsmand J.J., Amorim O.J.B. (2018) Silver (nano)materials Cause Genotoxicity In Enchytraeus crypticus, As Determined By the Comet Assay.
ENVIRONMENTAL TOXICOLOGY AND CHEMISTRY, 37
, (1), 184-191.
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Castro D., Mieiro C.L., Coelho J.P., Guilherme S., Marques A., Santos M.A., Duarte A.C., Pereira E., Pacheco M. (2018) Addressing the impact of mercury estuarine contamination in the European eel (Anguilla anguilla L., 1758) - An early diagnosis in glass eel stage based on erythrocytic nuclear morphology.
MARINE POLLUTION BULLETIN, 127
733-742.
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Costa R., Pereira J.L., Santos M.A., Pacheco M., Guilherme S. (2018) The role of contamination history and gender on the genotoxic responses of the crayfish Procambarus clarkii to a penoxsulam-based herbicide.
ECOTOXICOLOGY, 27
, (7), 908-918.
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Marques A., Pilo D., Carvalho S., Araujo O., Guilherme S., Santos M.A., Vale C., Pereira F., Pacheco M., Pereira P. (2018) Metal bioaccumulation and oxidative stress profiles in Ruditapes philippinarum - insights towards its suitability as bioindicator of estuarine metal contamination.
ECOLOGICAL INDICATORS, 95
1087-1099.
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Cappello T., Brandao F., Guilherme S., Santos M.A., Maisano M., Mauceri A., Canario J., Pacheco M., Pereira P. (2016) Insights into the mechanisms underlying mercury-induced oxidative stress in gills of wild fish (Liza aurata) combining H-1 NMR metabolomics and conventional biochemical assays.
SCIENCE OF THE TOTAL ENVIRONMENT, 548
13-24.
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Marques A., Pilo D., Araujo O., Pereira F., Guilherme S., Carvalho S., Santos M.A., Pacheco M., Pereira P. (2016) Propensity to metal accumulation and oxidative stress responses of two benthic species (Cerastoderma edule and Nephtys hombergii): are tolerance processes limiting their responsiveness?.
ECOTOXICOLOGY, 25
, (4), 664-676.
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Marques A., Rego A., Guilherme S., Gaivao I., Santos M.A., Pacheco M. (2016) Evidences of DNA and chromosomal damage induced by the mancozeb-based fungicide Mancozan (R) in fish (Anguilla anguilla L.).
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 133
52-58.
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Pereira R., Guilherme S., Brandao F., Raimundo J., Santos M.A., Pacheco M., Pereira P. (2016) Insights into neurosensory toxicity of mercury in fish eyes stemming from tissue burdens, oxidative stress and synaptic transmission profiles.
MARINE ENVIRONMENTAL RESEARCH, 113
70-79.
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Guilherme S., Santos M.A., Gaivao I., Pacheco M. (2015) Genotoxicity evaluation of the herbicide Garlon((R)) and its active ingredient (triclopyr) in fish (Anguilla anguilla L.) using the comet assay.
ENVIRONMENTAL TOXICOLOGY, 30
, (9), 1073-1081.
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Guilherme S., Santos M.A., Gaivao I., Pacheco M. (2014) DNA and chromosomal damage induced in fish (Anguilla anguilla L.) by aminomethylphosphonic acid (AMPA)-the major environmental breakdown product of glyphosate.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 21
, (14), 8730-8739.
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Pereira P., Pablo H., Guilherme S., Carvalho S., Santos M.A., Vale C., Pacheco M. (2014) Metal accumulation and oxidative stress responses in Ulva spp. in the presence of nocturnal pulses of metals from sediment: A field transplantation experiment under eutrophic conditions.
Marine Environmental Research, 94
56-64.
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Marques A., Custodio M., Guilherme S., Gaivao I., Santos M.A., Pacheco M. (2014) Assessment of chromosomal damage induced by a deltamethrin-based insecticide in fish (Anguilla anguilla L.) - A follow-up study upon exposure and post-exposure periods.
PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY, 113
40-46.
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Marques A., Guilherme S., Gaivao I., Santos M.A., Pacheco M. (2014) Progression of DNA damage induced by a glyphosate-based herbicide in fish (Anguilla anguilla) upon exposure and post-exposure periods - Insights into the mechanisms of genotoxicity and DNA repair.
COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-TOXICOLOGY & PHARMACOLOGY, 166
126-133.
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Guilherme S., Santos M.A., Gaivao I., Pacheco M. (2014) Are DNA-damaging effects induced by herbicide formulations (Roundup (R) and Garlon (R)) in fish transient and reversible upon cessation of exposure?.
AQUATIC TOXICOLOGY, 155
213-221.
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Guilherme S., Gaivão I., Santos M.A., Pacheco M. (2012) DNA damage in fish (Anguilla anguilla) exposed to a glyphosate-based herbicide – Elucidation of organ-specificity and the role of oxidative stress.
Mutation Research/Genetic Toxicology And Environmental Mutagenesis, 743
1-9.
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Costa P., Pereira P., Guilherme S., Barata M., Nicolau L., Santos M.A., Pacheco M., Pousão-Ferreira P. (2012) Biotransformation modulation and genotoxicity in white seabream upon exposure to paralytic shellfish toxins produced by Gymnodinium catenatum.
Aquatic Toxicology, 106
42-47.
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Guilherme, S., Santos, M.A., Barroso, C., Gaivão, I., Pacheco, M. (2012) Differential genotoxicity of Roundup® formulation and its constituents in blood cells of fish (Anguilla anguilla): considerations on chemical interactions and DNA damaging mechanisms.
Ecotoxicology, 21
, (5), 1381-1390.
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Guilherme S. , Gaivão I., Santos M.A., Pacheco M. (2010) European eel (Anguilla anguilla) genotoxic and pro-oxidant responses following short-term exposure to Roundup® - a glyphosate-based herbicide.
Mutagenesis, 25
, (5), 523-530.
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Pereira C., Guilherme S., Barroso C., Verschaeve L., Pacheco M., Mendo S. (2010) Evaluation of DNA Damage Induced by Environmental Exposure to Mercury in Liza aurata Using the Comet Assay.
Archives Of Environmental Contamination And Toxicology, 58
, (1), 112-122.
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Guilherme S. , Gaivao I., Santos M.A., Pacheco M. (2009) Tissue specific DNA damage in the European eel (Anguilla anguilla) following a short-term exposure to a glyphosate-based herbicide.
Toxicology Letters, 189
, (Suppl. 1), S212-S212.
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Guilherme S., Válega M. , Pereira M.E. , Santos M.A., Pacheco M. (2008) Erythrocytic nuclear abnormalities in wild and caged fish (Liza aurata) along an environmental mercury contamination gradient.
Ecotoxicology And Environmental Safety, 70
, (3), 411-421.
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Guilherme S. , Válega M. , Pereira M.E. , Santos M.A., Pacheco M. (2008) Antioxidant and biotransformation responses in Liza aurata under environmental mercury exposure – relationship with mercury accumulation and implications for public health.
Marine Pollution Bulletin, 396
, (1), 70-78.
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Sofia Isabel Antunes Gomes Guilherme
Investigadora Auxilar
- Researcher ID: P-8577-2018
- ORCID: 0000-0002-3238-4462
- Ciencia ID:
- Departamento: Biologia
- Grupo de Investigação: Ecotoxicologia
- ISI Web of KnowledgeSM search factor: AU=(Guilherme S and Pacheco M)
Interesses de investigação
- Pesticides
- Oxidative Stress
- Genotoxicity
- Epigenetics
- Aquatic Ecosystems
- Oxidative Stress
- Genotoxicity
- Epigenetics
- Aquatic Ecosystems
Graus académicos
- 2012, PhD, University of Aveiro
- 2007, Master in Toxicology, University of Aveiro
- 2002, First Degree in Biology and Geology, University of Aveiro
- 2007, Master in Toxicology, University of Aveiro
- 2002, First Degree in Biology and Geology, University of Aveiro
Atividades científicas
- 01-02-2019 to present Contract Researcher under Decree-Law 57/2016 Art.23rd - Transitional Rule at University of Aveiro and CESAM
- 01-11-2013 to 30-01-2019 Post-doctoral research fellow at University of Aveiro and CESAM (grant ref SFRH/BPD/88947/2012)
- 01-2-2013 to 01-10-2013 Research fellow at University of Aveiro and CESAM
(project ref PTDC/AAC-AMB/114123/2009)
- 01-5-2008 to 01-9-2012 PhD research fellow at University of Aveiro and CESAM
(grant ref SFRH/BD/42103/2007)
- 01-11-2013 to 30-01-2019 Post-doctoral research fellow at University of Aveiro and CESAM (grant ref SFRH/BPD/88947/2012)
- 01-2-2013 to 01-10-2013 Research fellow at University of Aveiro and CESAM
(project ref PTDC/AAC-AMB/114123/2009)
- 01-5-2008 to 01-9-2012 PhD research fellow at University of Aveiro and CESAM
(grant ref SFRH/BD/42103/2007)
Outros
- High experience in field work
- High experience in laboratorial work
- Frequent reviewer of papers submitted to scientific journals
- Assistance of several advanced courses
- Specialized Monitor in "Academia de Verão" - Universidade de Aveiro
- Invited Lecturer in initiatives to raise awareness of the society to environmental health problems
- High experience in laboratorial work
- Frequent reviewer of papers submitted to scientific journals
- Assistance of several advanced courses
- Specialized Monitor in "Academia de Verão" - Universidade de Aveiro
- Invited Lecturer in initiatives to raise awareness of the society to environmental health problems
Publicações
Artigos WoS
(26)
Outros artigos
(1)
Livros
(0)
Capítulo de Livro
(1)
Teses
(6)
Comunicações
(33)
Outras Publicações
(1)
Relatórios
(0)
Projetos
Orientações científicas
Master (Orientador Principal):
Rodrigo Crespo
(not a CESAM member)
Master (Orientador Principal):
Párástu Oskoei
(not a CESAM member)
Master (Orientador Principal):
Ricardo Costa
(not a CESAM member)
Master (Co-orientador):
Vitória Pereira
(not a CESAM member)
Graduation (Orientador Principal):
Bruno Monteiro
(not a CESAM member)
Graduation (Orientador Principal):
Graça Oliveira
(not a CESAM member)
Graduation (Orientador Principal):
Párástu Oskoei
(not a CESAM member)
Graduation (Orientador Principal):
Mélanie Ferreira
(not a CESAM member)
Graduation (Orientador Principal):
Tânia Vicente
(not a CESAM member)
Graduation (Co-orientador):
José Portela
(not a CESAM member)
Graduation (Co-orientador):
Guilherme Teixeira
(not a CESAM member)
Internship (Co-orientador):
Párástu Oskoei
(not a CESAM member)
Intership (Co-orientador):
Mélanie Ferreira
(not a CESAM member)
Intership (Co-orientador):
Mélanie Ferreira
(not a CESAM member)
PhD (Co-orientador):
Ana Raquel Marçal
(CESAM member)
