|BEAUTY: Big gEnome wide Applications for an ecotoxicology soil model – a knowledge base to Unravel mechanisms (nanopesTY_cides)|
Programme - OE- Fundos Nacionais
Execution dates - 2021-03-29 - 2024-03-28 (36 Months)
Funding Entity - FCT - Fundação para a Ciência e a Tecnologia
Funding for CESAM - 249954 €
Total Funding - 249954 €
Proponent Institution - Universidade de Aveiro
Aarhus University (AU)
Babraham Institute (BI)
Universidade Estadual Paulista (UNESP)
BEAUTY aims to unravel the mechanisms of action of stressors identifying adverse outcome pathways (AOPs). This will move risk assessment-RA from the current approach to a much more informed decision making, enabling to transfer key information between RA of related stressors. For the highly ecologically important invertebrate species, Enchytraeus crypticus, we will use analytical information from internal biological levels (genomics to phenomics) to develop AOPs via pathway network analysis.
Since, this ecotoxicology standard species has just become a full genome model (we sequenced its genome) we can use the most advanced techniques to support our studies. This will be supported by studies at the functional level, which will add further supporting evidences or close the cycle.
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