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title The cytotoxic targets of anatase or rutile plus anatase nanoparticles depend on the plant species
authors Silva, S; Oliveira, H; Silva, AMS; Santos, C
author full name Silva, S.; Oliveira, H.; Silva, A. M. S.; Santos, C.
title The cytotoxic targets of anatase or rutile plus anatase nanoparticles depend on the plant species
nationality internacional
language English
document type Article
author keywords abiotic stress; cell cycle; genotoxicity; micronucleus; phytotoxicity; titanium dioxide
abstract The potential toxicity of nanoparticles (NPs) is under debate. Information about TiO2 NPs phytotoxicity is still limited partly due to the different TiO2 NP forms that may be found in the environment. The present work investigated the impact of different TiO2 NPs forms (rutile and anatase) on germination, growth, cell cycle profile, ploidy level, and micronucleus formation in Lactuca sativa (lettuce) and Ocimum basilicum (basil). Seeds were exposed to anatase (ana) or rutile + anatase (rut+ana) at concentrations 5 - 150 mg dm(-3) for 5 d and after that different parameters were analyzed. Rut+ana showed high potential to impair germination and growth. On the other hand, ana alone showed a positive influence on seedling growth. Despite that, ana induced severe alterations in cell cycle dynamics. Regarding species, basil was more sensitive to TiO2 NPs cytostatic effects (delay/arrest in G(0)/G(1) phase), whereas in lettuce, TiO2 NPs were more genotoxic (micronucleus formation increase). Finally, we propose that, besides germination and plant growth, cell cycle dynamics and micronucleus formation can be sensitive biomarkers of these NPs.
author address [Silva, S.; Silva, A. M. S.] Univ Aveiro, Dept Chem, QOPNA, P-3810193 Aveiro, Portugal; [Silva, S.; Oliveira, H.] Univ Aveiro, CESAM, P-3810193 Aveiro, Portugal; [Oliveira, H.] Univ Aveiro, Dept Biol, P-3810193 Aveiro, Portugal; [Santos, C.] Univ Porto, Dept Biol, Fac Sci, P-4169007 Oporto, Portugal
reprint address Silva, S (reprint author), Univ Aveiro, Dept Chem, QOPNA, P-3810193 Aveiro, Portugal.; Silva, S (reprint author), Univ Aveiro, CESAM, P-3810193 Aveiro, Portugal.
e-mail address soniasilva@ua.pt
researcherid number Silva, Artur/L-9222-2014
orcid number Silva, Artur/0000-0003-2861-8286; Santos, Conceicao/0000-0003-4129-6381; Silva, Sonia/0000-0003-1291-2667; Oliveira, Helena/0000-0002-4673-0696
funding agency and grant number Fundacao para a Ciencia e Tecnologia/Ministerio da Ciencia, Tecnologia e Ensino Superior (FCT/MCTES) from the financing program QREN-POPH/FSE - Tipologia 4.1 - Formacao Avancada [SFRH/BPD/74299/2010, SFRH/BPD/111736/2015]; CESAM [UID/AMB/50017]; UI QOPNA [FCT UID/QUI/00062/2013]; FCT/MEC; FEDER; Compete; FEDER/COMPET/POCI [POCI-01-0145-FEDER-006958 (UID/AGR/04033/2013)]
funding text Fundacao para a Ciencia e Tecnologia/Ministerio da Ciencia, Tecnologia e Ensino Superior (FCT/MCTES) supported S. Silva (SFRH/BPD/74299/2010) and H. Oliveira (SFRH/BPD/111736/2015) grants from the financing program QREN-POPH/FSE - Tipologia 4.1 - Formacao Avancada. We want to thank for the for the financial support to CESAM (UID/AMB/50017) and UI QOPNA (FCT UID/QUI/00062/2013), to FCT/MEC through national funds and co-funding by the FEDER, within the PT2020 Partnership Agreement and Compete 2020. This work was also funded by FEDER/COMPET/POCI, POCI-01-0145-FEDER-006958 (UID/AGR/04033/2013).
cited references Anjum NA, 2015, ENVIRON RES, V138, P306, DOI 10.1016/j.envres.2015.02.019; Ardakani AS, 2013, NEMATOLOGY, V15, P671, DOI 10.1163/15685411-00002710; Bandyopadhyay S, 2015, SCI TOTAL ENVIRON, V515, P60, DOI 10.1016/j.scitotenv.2015.02.014; Barrena R, 2009, CHEMOSPHERE, V75, P850, DOI 10.1016/j.chemosphere.2009.01.078; Begum P., 2009, NANOMATERIALS, V4, P203; Bourikas K, 2014, CHEM REV, V114, P9754, DOI 10.1021/cr300230q; Castiglione MR, 2011, J NANOPART RES, V13, P2443, DOI 10.1007/s11051-010-0135-8; Chen J, 2015, J HAZARD MATER, V297, P173, DOI 10.1016/j.jhazmat.2015.04.077; Clement L, 2013, CHEMOSPHERE, V90, P1083, DOI 10.1016/j.chemosphere.2012.09.013; Cox A, 2016, PLANT PHYSIOL BIOCH, V107, P147, DOI 10.1016/j.plaphy.2016.05.022; Cui D, 2014, ENVIRON SCI-NANO, V1, P459, DOI [10.1039/C4EN00025K, 10.1039/c4en00025k]; Cui D, 2014, J ZHEJIANG UNIV-SC A, V15, P662, DOI 10.1631/jzus.A1400114; Fan RM, 2014, SCI TOTAL ENVIRON, V466, P503, DOI 10.1016/j.scitotenv.2013.07.032; Feizi H, 2013, CHEMOSPHERE, V91, P506, DOI 10.1016/j.chemosphere.2012.12.012; Feizi H, 2012, BIOL TRACE ELEM RES, V146, P101, DOI 10.1007/s12011-011-9222-7; Foltete AS, 2011, ENVIRON POLLUT, V159, P2515, DOI 10.1016/j.envpol.2011.06.020; Frazier TP, 2014, FUNCT INTEGR GENOMIC, V14, P75, DOI 10.1007/s10142-013-0341-4; Garcia A, 2011, DESALINATION, V269, P136, DOI 10.1016/j.desal.2010.10.052; Garcia-Sanchez S, 2015, BMC GENOMICS, V16, DOI 10.1186/s12864-015-1530-4; Ghosh M, 2010, CHEMOSPHERE, V81, P1253, DOI 10.1016/j.chemosphere.2010.09.022; Gottschalk F, 2013, ENVIRON POLLUT, V181, P287, DOI 10.1016/j.envpol.2013.06.003; Handy RD, 2012, ECOTOXICOLOGY, V21, P933, DOI 10.1007/s10646-012-0862-y; Hanif HU, 2015, PAK J AGR SCI, V52, P177; Hawthorne J, 2012, INT J PHYTOREMEDIAT, V14, P429, DOI 10.1080/15226514.2011.620903; Hurum DC, 2003, J PHYS CHEM B, V107, P4545, DOI 10.1021/jp0273934; Jiang CJ, 2014, INT J MOL SCI, V15, P13967, DOI 10.3390/ijms150813967; Jiang HS, 2014, ENVIRON TOXICOL CHEM, V33, P1398, DOI 10.1002/etc.2577; Kurepa J, 2010, NANO LETT, V10, P2296, DOI 10.1021/nl903518f; Larue C, 2014, J HAZARD MATER, V273, P17, DOI 10.1016/j.jhazmat.2014.03.014; Larue C, 2012, J TOXICOL ENV HEAL A, V75, P722, DOI 10.1080/15287394.2012.689800; Larue C, 2012, SCI TOTAL ENVIRON, V431, P197, DOI 10.1016/j.scitotenv.2012.04.073; Lopez-Moreno ML, 2010, ENVIRON SCI TECHNOL, V44, P7315, DOI 10.1021/es903891g; Loureiro J, 2007, ANN BOT-LONDON, V100, P875, DOI 10.1093/annbot/mcm152; Ma CX, 2015, ENVIRON SCI TECHNOL, V49, P7109, DOI 10.1021/acs.est.5b00685; Ma YH, 2015, NANOTOXICOLOGY, V9, P262, DOI 10.3109/17435390.2014.921344; Miralles P, 2012, ENVIRON SCI TECHNOL, V46, P9224, DOI 10.1021/es202995d; Mohammadi R, 2014, RUSS J PLANT PHYSL+, V61, P768, DOI 10.1134/S1021443714050124; Moreno-Olivas F, 2014, J ZHEJIANG UNIV-SC A, V15, P618, DOI 10.1631/jzus.A1400159; Nair PMG, 2015, BIOL PLANTARUM, V59, P591, DOI 10.1007/s10535-015-0494-1; Pakrashi S, 2014, PLOS ONE, V9, DOI 10.1371/journal.pone.0087789; Palmqvist NGM, 2015, SCI REP-UK, V5, DOI 10.1038/srep10146; Panda KK, 2011, TOXICOL IN VITRO, V25, P1097, DOI 10.1016/j.tiv.2011.03.008; Parveen A, 2015, J CLUST SCI, V26, P693, DOI 10.1007/s10876-014-0728-y; Ricci PC, 2013, J PHYS CHEM C, V117, P7850, DOI 10.1021/jp312325h; Seeger E, 2009, J SOIL SEDIMENT, V9, P46, DOI 10.1007/s11368-008-0034-0; Servin AD, 2012, ENVIRON SCI TECHNOL, V46, P7637, DOI 10.1021/es300955b; Shi HB, 2013, PART FIBRE TOXICOL, V10, DOI 10.1186/1743-8977-10-15; Silva S, 2016, CHEMOSPHERE, V151, P68, DOI 10.1016/j.chemosphere.2016.02.047; Song U, 2013, BIOL TRACE ELEM RES, V155, P93, DOI 10.1007/s12011-013-9765-x; Srivastava V, 2015, IND ENG CHEM RES, V54, P6209, DOI 10.1021/acs.iecr.5b01610; Sun TY, 2015, ENVIRON SCI-NANO, V2, P340, DOI 10.1039/c5en00004a; Tumburu L, 2015, ENVIRON TOXICOL CHEM, V34, P70, DOI 10.1002/etc.2756; Vannini C, 2014, J PLANT PHYSIOL, V171, P1142, DOI 10.1016/j.jplph.2014.05.002; Weir A, 2012, ENVIRON SCI TECHNOL, V46, P2242, DOI 10.1021/es204168d; Yang F, 2007, BIOL TRACE ELEM RES, V119, P77, DOI 10.1007/s12011-007-0046-4
cited reference count 55
times cited 2
total times cited count (wos, bci, and cscd) 2
publisher city PRAHA 6
publisher address ROZVOJOVA 263, PRAHA 6, CZ-165 02, CZECH REPUBLIC
issn 0006-3134
29-character source abbreviation BIOL PLANTARUM
iso source abbreviation Biol. Plant.
publication date DEC
year published 2017
volume 61
issue 4
beginning page 717
ending page 725
digital object identifier (doi) 10.1007/s10535-017-0733-8
subject category 9
document delivery number Plant Sciences
unique article identifier Plant Sciences
CESAM authors