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Sónia Mendo

Sónia Mendo

Assistant Professor with Habilitation

  • Department: Biology
  • Research Group: Stress Biology
  • ISI Web of KnowledgeSM search factor : Author=(Mendo S) AND Address=(Aveiro)


Researcher ID

E-1095-2011

OTHER ACTIVITIES ( Organization of scientific events)

XIII Congresso Ibérico de Citometria de Fluxo (SIC), 9 - 11 may 2013


Member of the organizing committee of Congresso Nacional de Microbiologia e Biotecnologia, 6 - 8 december 2013.

1st INTERNATIONAL SYMPOSIUM BIOLOGICAL RESPONSES TO CHEMICAL CONTAMINANTS: FROM MOLECULAR TO COMMUNITY LEVEL

Interdisciplinary Symposium BIOLOGICAL RESPONSES TO CHEMICAL CONTAMINANTS: from molecular to community level, September 2-4, 2009 Aveiro University, Portugal



  • TOPICS: 1. BACTERIAL RESPONSES  Pollutant degradation  Resistance to chemicals 2. EUKARYOTIC RESPONSES  Response to contaminants in animals INVITED SPEAKERS JI-DONG GU, University of Hong Kong, Hong Kong CHIEH-CHEN HUANG, National Chung Hsing University, Taiwan KORNELIA SMALLA, Federal Biological Research Center for Agriculture and Forestry (BBA), Germany MARKO VIRTA, University of Helsinki, Finland HISATO IWATA, Ehime University, Japan NEWTON GOMES, Aveiro University, Portugal RUTH PEREIRA, Aveiro University, Portugal ISABEL HENRIQUES, Aveiro University, Portugal CORINA CIOCAN, University of Sussex, UK J.M.RUIZ, University of la Coruna, Spain


 


 



  • 77 national and international researchers from Spain,UK, Finland, France, Germany and Japan, participarted at the event.

PROJECT: POCI/MAR/56475/2004 (POCI2010/FEDER)


  • MAIN RESULTS: Isolation, identification and characterization of TBT resistant/tolerant culturable bacteria A significant difference was observed between isolates belonging to the same genera. No significant correlation between strains isolated from a more polluted area (water) and strains collected at the less polluted area (sediment). Medium-organometal interactions may affect metal toxicities. Despite the heterogeneity Gram negative and are generally more resistant to TBT. Memory response to TBT exposure We proposed the existence of a ‘memory response’ mechanism to TBT/toxicant exposure. Nonetheless, the relation between the ‘memory response’ to TBT concentration and the resistant bacteria on a given natural environment could not be made as other factors (presence of other toxic compounds) could influence the ‘memory’ mechanism response. A. molluscorum Av27 was selected for a series of studies due to its high TBT resistance and also to the ability to degrade it to lesser toxic compounds (DBT and MBT). TBT microbial community-level toxicity and degradation DGGE (37-65%) analysis of microcosm communities showed that the time interval applied to autoclaved samples was not enough to eliminate all the bacteria present. Possibly, sporulating/slow growing anaerobic bacteria were not destroyed and were able to grow after some time of incubation. Also the organic matter present in the microcosm could protect some of bacteria, as growth was detected after 30 days of incubation. The TBT concentration used seems to be lethal to some bacteria after 5 days, as a decrease of the bacterial community was observed (samples 7, 8 and 22, 23). However, after 30 days, the community recovered, maybe due to the lower concentration of TBT due to its degradation by bacteria that were still present. The addition of Av27 did not seem to have an impact, maybe because A. molluscorum is already part of the original (microcosm) community, and possibly is not a dominant bacteria in that environment. Characterization of bacterial abundance, viability, activity and functional diversity Bacterial viability analysis showed that TBT has influence on cells as they were smaller and appeared aggregated. This could be explained as an energy saving mechanism exhibited by the bacteria when exposed to TBT for long periods. Despite their resistance to TBT, bacteria cells are growing under stress conditions, due to the scarcity of nutrients. Other experimental results suggested that in TSB (rich) medium the cells can have a better performance, meaning that maybe the components of the medium can protect the cell to TBT exposition, by chelating TBT from the environment were cells are growing. TBT degradation Degradation of TBT in DBT occurred under laboratory conditions by A. molluscorum Av27, after 24 h in MB medium. Also, it seems that it is gradually exported, as DBT, after degradation inside the cell. This possibility was not proved yet due to some technical problems. Despite the debutylation of TBT results in less lipophilic compounds, due to cell activity, it appears that these compounds are still bound to the cell membrane lipids. The TBT degradation was compared when Av27 was growing in TSB (rich medium) and in MB. Results, demonstrated a higher degradation in MB medium suggesting that the rich medium does not promote an increase on TBT degradation. However, metabolic activity determinations suggested that TSB protects the cells from the TBT toxicity. Isolation and characterization of the genes involved in TBT resistance TBT resistance seems to be related with a gene that has high homology with sugE gene. RT-PCR and real time PCR analysis showed an increased expression of this gene, as revealed by an increase of the mRNA level when cells are grown in increasing TBT concentrations. This gene is part of the “small multidrug resistance family” (SMR) that has been described as being involved in the efflux of lipophilic drugs. It seems apparent that SugE-like protein plays a role in the transport of TBT, DBT or MBT outside or inside the bacterial cell, this mechanism is not elucidated yet. Total proteins analysis from cells of clone 69 growing in the presence of TBT, revealed that a protein of ~ 11 kDa is overexpressed. This protein could be related to the sugE (encoded on ORF P6). Other proteins are also overexpressed, 2 of those were identified as outer membrane proteins that could be related with the influx and efflux of TBT and also with its degradation products( DBT and MBT) from or into the cell. Another protein, ~ 57 kDa, was identified: groEL protein. This protein is a chaperonin with a major role on the renaturation of proteins, restoring its functional activity at the expense of ATP seems to be overexpressed due to TBT. TBT resistance: is the same resistance mechanism shared by other Aeromonas spp.? The same gene was found in bacteria of the same species. However different mechanism(s) might be responsible for TBT resistance in other Aeromonas spp.

ISOLATION AND CHARACTERIZATION OF THE GENES INVOLVED IN TRIBUTYLTIN- TBT- RESISTANCE IN MARINE BACTERIA POCI/MAR/56475/2004 (POCI2010/FEDER)


  • ABSTRACT: The main objective of this project is to study and understand the behaviour and the mechanisms behind TBT resistance by marine estuarine bacteria. The approach will include the isolation of culturable marine bacterial isolates that will allow for the detection and isolation of the genes involved in TBT resistance. Additionally bacterial communities will also be studied as they constitute the base of aquatic food webs and are responsible for the bulk of organic matter transformations and mineral recycling in aquatic environments. Also, due to the various sensitivities of different microorganisms to toxic chemicals and the dominance of highly diverse microbes in natural environments and, bacterial community responses to the toxic effect of TBT will also be analyzed. Specific objectives are related and constitute specific work tasks: i) Isolation, identification and characterization of TBT resistant/tolerant culturable bacteria A from where a collection of TBT resistant/tolerant bacteria will be selected for further studies ii) Microbial community-level toxicity testing where community-level toxicity testing of chemicals should supplement single-species laboratory assays when testing potential harmful chemicals like TBTs, iii) Characterization of bacterial abundance, viability, activity and functional diversity designed to compare bacterial density, viability, activity and functional diversity of bacterial communities in coastal waters in order to evaluate the effect of TBT on bacterial metabolism, iv) TBT degradation assay to demonstrate the mechanism behind TBT resistance/tolerance by marine bacteria and v) Isolation and characterization of the genes involved in TBT resistance. It is well known that isolation and culturing techniques miss out a large part of the bacterial community. Therefore the use of molecular techniques will enable us to select interesting organisms for a future construction of microbial consortia with TBT degrading capabilities. The proposed study will allow for the isolation of the encoded TBT resistance genes in marine bacteria that is of extreme importance for future research.

FCT PUBLIC KEY


  • J0013655185

POST GRADUATION SUPERVISION


  • Scientific Supervisor of more than 30 MSc students and 6 PhD (all concluded)

  • Presently supervising, 2 Post Dc, 3 PhD and 5 MSc students.

RESEARCH PROJECTS

PARTICIPATE/ED AS TEAM MEMBER IN THE FOLLOWING RESEARCH PROJECTS:



  • Projecto Icentro: Redução do teor de sulforoso de vinhos. Funded by IC-01-01_FDR-0153 (Mar 2008-Jun 2009)

  • Projecto QREN : "WineSulFree" - Avaliação de tecnologias que permitam a redução do teor de sulfitos dos vinhos -Financiado pelo QREN - SI I&DT Co-Promoção (projecto nº3462), Agosto de 2009-2011).

  • WineSulFree - Establishment of the scientific basis for the development of new technologies to substitute sulphur dioxide in wine. Projectos I&D PTDC/AGR-ALI/101251/2008

  • Projecto Sal do Atlântico: "Revalorização da identidade das salinas do atlântico. Recuperação e promoção do potencial biológico, económico e cultural das zonas húmidas costeiras" (Programa comunitário de apoio Interreg III B Espaço Atlântico) (2004-2007)

  • Diferenciação Genética e morfológica em organismos estuarinos com padrões de dispersão contrastantes ao longo de um gradiente geográfico. Projecto POCTI/BSE/45672/2002 (2003-2006); Projecto de I&D da Universidade de Aveiro, Abordagem molecular para despistagem de bactérias patogénicas, OE 3.64.33.8 (2003-2005)

  • Conservação e valorização dos recursos genéticos de pomóideas regionais. Projecto do Programa AGRO; Medida 8-Desenvolvimento Tecnológico e Demonstração; Acção 8.1- Desenvolvimento Experimental e Demonstração - DE&D (2001-2004)

  • Projecto REI- Ensaios de reflorestação da Ilha de Porto Santo usando plantas autócnes regeneradas in vitro e adaptadas a stress hídrico, PNAT/1999/AGR/15011 (2000-2004); Estudo da função de uma alteração ao código genético na evolução de novos fenótipos em Candida albicans, Projecto Praxis/P/BIA/1139/1998 (1999- 2001).


PRINCIPAL INVESTIGATOR OF THE FOLLOWING RESEARCH PROJECTS:



  • Isolation and caracterisation of the genes involved in tributyltin (TBT) in marine bacteria. POCI/MAR/56475/2004, started in October, 2005; Total Budget: 54K€.

  • TBTRESENSE - Bioremediation of TBT development of a biosensor system to detect TBT form contaminates sites (PTDC/MAR/108024/2008); started in April, 2005; Total Budget: 176K€

  • ENGENUR: Definition of new endpoints to assess and discriminate genotoxic effects resulting from environmental exposures to uranium, uranium daughter radionuclides and ionizing radiation in bioindicator species. Projecto PTDC/AAC-AMB/114057/2009. 172.944 €; Janeiro 2011-Janeiro 2013.Total Budget: 173K€

ACTIVITIES/POSITIONS


  • Assistant Professor with Habilitation, Department of Biology, University of Aveiro (since 2013)

  • Assistant Professor, Department of Biology, University of Aveiro (since 1999)

  • Chaiman of the board of equivalences of the Department of Biology, University of Aveiro (since 2004)

  • Coordinator of the MSc Degree in Molecular Microbiology, Department of Biology, University of Aveiro (3rd to 5th editions)

  • Committee Member of the  of the MSc in Microbiology, Department of Biology, University of Aveiro (since 2007)

  • Director of the MSc in MIcrobiology, Department of Biology, University of Aveiro (since September 2011)

  • National coordinator of COST (CM0804), Chemical Biology with Natural Products

Habilitation in Biology


  • BSc Honours in Microbiology (1989), University of Kent, Caterbury, UK; 

  • PhD in Biology – Microbial Biotechnology (1998), Faculty of Sciences, University of Lisbon;

  • Habilitation in BIology (January 2013)

MAIN RESEARCH ACTIVITY AND INTERESTS

Scopus Author ID: 6505928827:https://www.scopus.com/authid/detail.uri?authorId=6505928827


ORCID: 


Google Scholar: https://scholar.google.pt/citations?user=SgLu4HQAAAAJ&hl=pt-BR


Researcher ID: http://www.researcherid.com/rid/E-1095-2011



  • Search for new antimicrobials: Lantibiotics and traditional antibiotics;

  • Resistance mechanisms to xenobiotics in bacteria;

  • Genotoxicity studies in vertebrates and invertebrates exposed to environmental contaminants.

Born in Lobito, Angola, 16th December 1962. Married, two children. BSc in Microbiology (1989) University of Kent at Canterbury, UK. Ph.D. (1998) in Biology -Microbial Biotechnology, University of Lisbon. Habilitation (2013), University of Aveiro. Since 2000, Assistant Professor at Biology Department of the University of Aveiro. 

Scientific Supervision

In progress
Concluded

Projects

In progress
  • NANOpartículas poliméricas BIogénicas funcionalizadas para adsorção de metais em aplicações amigas do ambiente: bioREmediação e bioSensores See more
Concluded
  • Coli4Lan - Better systems to produce two ­peptide lantibiotics with diverse structures completely in vivo using Escherichia coli and establishment of their mode of action. See more
  • REpulse- Responses of Daphnia magna exposed to chemical pulses and mixtures throughout generations See more
  • ECOAPPROACH - Bridging the gap between metal contamination and ecologically significant effects on macrobenthic communities: a multidisciplinary approach from gene to community See more
  • ENGENUR - Definition of new ENdpoints to assess and discriminate GENotoxic effects resulting from environmental exposures See more
  • TBTRESENSE: Tributiyltin (TBT) bioremediation and development of a biosensor to detect TBT from contaminated sites. See more
  • Remediation Processes in uranium and other mining areas See more
  • CAPTAR-Science and Environment for All See more
  • Isolation and Characterization of the genes involved in TBT resistance in marine bacteria See more
  • Ecological risk assessment on the use of boat antifouling paints with organometallic and metallic biocides at the Portuguese coast (ECOBOAT) See more
  • “Salt of the Atlantic”: Revalorization of identity of the Atlantic Saltpans. Recuperation and promotion of biological, economic and cultural potential of coastal wetlands See more

Publications

WoS Papers (69)
Sousa A., Mendo S., Barroso C.M. (2005) Imposex and organotin contamination in Nassarius reticulatus (L.) along the Portuguese coast . In: Applied Organometallic Chemistry. 19, 315-323.
Sousa A., Génio L., Mendo S., Barroso C.M. (2005) Comparison of the acute toxicity of tributyltin (TBT) and copper to veliger larvae of Nassarius reticulatus (L.). In: Applied Organometallic Chemistry. 19, 324-328.
Barroso C.M., Mendo S., Moreira M.H. (2004) Organotin contamination in the mussel Mytilus galloprovincialis from Portuguese coastal waters. In: Marine Pollution Bulletin . 48, 1149-1153.
Caetano T., Ferreira S., Mondego A.P., Correia A., Mendo S. (2007) In99 an In100 related-integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from Portugal. In: Epidemiol Infect. 135, 3, 502-504.
Nogueira P.R., Lourenço J., Mendo S., Rotchell J.M. (2006) Mutation analysis of ras gene in the liver of European eel (Anguilla anguilla L.) exposed to benzo[a]pyrene. In: Marine Pollution Bulletin . 12, 52, 1611-1616.
Mendo, S., Henriques I., Correia A., Duarte J.M. (2000) Genetic characterization of a new thermotolerant Bacillus licheniformis strain. In: Current Microbiology . 40, 137-139.
Mendo S., Faustino N.A., Sarmento A.C., Amado F., Moir A.J.G (2004) Purification and characterization of a new peptide antibiotic produced by a thermotolerant Bacillus licheniformis strain. In: Biotechnology Letters. 26, 2, 115-119.
Cruz A., Caetano T., Suzuki S., Mendo S. (2007) Aeromonas veronii, a tributyltin (TBT)-degrading bacterium isolated from a estuarine environment, Ria de Aveiro in Portugal. In: Marine Environmental Research. 64, 639-650.
Alves E., Carvalho C. M. B., Tomé J. P. C., Faustino M. A. F., Neves M .G .P. S., Tomé A. C., Cavaleiro J. A. S., Cunha Â., Mendo S., Almeida A. (2008) Photodynamic inactivation of recombinant bioluminescent Escherichia coli by cationic porphyrins under artificial and solar irradiation. In: Journal Of Industrial Microbiology And Biotechnology. 35, 11, 1447-1454.
Pereira R., Marques C.R., Silva Ferreira M.J., Neves M.F.J.V., Caetano A.L., Antunes S.C., Mendo S., Gonçalves F. (2009) Phytotoxicity and genotoxicity of soils from an abandoned uranium mine area. In: Applied Soil Ecology. 42, 3, 209-220.
Nogueira P. R., Lourenço J., Rodriguez E., Pacheco M., Santos C., Rotchell J. M., Mendo S. (2009) Transcript profiling and DNA damage in the European eel (Anguilla anguilla L.) exposed to 7,12-dimethylbenz[a]anthracene. In: Aquatic Toxicology. 94, 2, 123-130.
Rodrigues A.M, Pires A., Mendo S., Quintino V. (2009) Diopatra neapolitana and Diopatra marocensis from the Portuguese coast: morphological and genetic comparison. In: Estuarine Coastal And Shelf Science. 85, 609-617.
Lourenço J., Castro B. B., Machado R., Nunes B., Mendo S., Gonçalves F., Pereira R. (2010) Genetic, biochemical and individual responses of the teleost fish Carassius auratus to uranium. In: Archives Of Environmental Contamination And Toxicology . 58, 4, 1023-1031.
Santos, C., Caetano, T., Ferreira, S., Mendo, S. (2010) Tn5090-like class 1 integron carrying bla(VIM-2) in a Pseudomonas putida strain from Portugal. In: Clinical Microbiology And Infection. 16, 10, 1558-1561.
Pascoal, S., Creer, S., Taylor, M. I., Queiroga, H., Carvalho, G., Mendo, S. (2009) Development and application of microsatellites in Carcinus maenas: genetic differentiation between northern and central Portuguese populations. In: Plosone. 4, 1, e7268
Ferreira S., Toleman M., Ramalheira E., da Silva G.J., Walsh T., Mendo S. (2010) First description of Klebsiella pneumoniae clinical isolates carrying both qnrA and qnrB genes in Portugal. (in press). In: International Journal Of Antimicrobial Agents. 35, 6, 584-586.
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T., Mendo S. (2010) Carriage of qnrA1 and qnrB2, bla CTX-M15, and complex class 1 integron in a clinical multiresistant Citrobacter freundii isolate. In: Diagnostic Microbiology And Infectious Disease . 67, 2, 188-190.
Nogueira P., Pacheco M., Pereira M.L., Mendo S. , Rotchell J.M. (2010) Anchoring novel molecular biomarker responses to traditional responses in fish exposed to environmental contamination. In: Environmental Pollution . 158, 5, 1783-1790.
Ferreira E., Rosenthal A. , Calado V., Saraiva, J., Mendo, S. (2009) Byssochlamys nivea inactivation in pineapple juice and nectar using high pressure cycles. In: Journal Of Food Engineering. 95, 4, 664-669.
Cruz A., Oliveira V., Baptista I., Almeida A., Cunha A., Suzuki S., Mendo S. (2012) Effect of tributyltin (TBT) in the metabolic activity of TBT-resistant and sensitive estuarine bacteria. In: Environmental Toxicology. 27, 1, 11-17.
Domingues I, Oliveira R, Lourenço J, Grisolia C, Mendo S, Soares A (2010) Biomarkers as a tool to assess effects of chromium (VI): Comparison of responses in zebrafish early life stages and adults. In: Comparative Biochemistry And Physiology, Part C. 152, 338-345.
Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2011) A novel complex class 1 integron found in a Klebsiella pneumoniae isolate from Portugal. In: Clinical Microbiology And Infection. 17, 7, 1036-1039.
Lourenço J., Pereira R., Silva A., Morgado J., Carvalho F., Oliveira J., Malta M., Paiva A., Mendo S., Gonçalves F. (2011) Genotoxic endpoints in the Earthworms Sub-Lethal Assay to Evaluate Natural Soils Contaminated by Metals and Radionuclides. In: Journal Of Hazardous Materials. 186, 1, 788-795.
Caetano T., Krawczyk J.M., Moesker E., Suessmuth R.D., Mendo S. (2011) Heterologous Expression, Biosynthesis, and Mutagenesis of Type II Lantibiotics from Bacillus licheniformis in Escherichia coli. In: Chemistry & Biology. 18, 1, 90-100.
Mendo S., Ferreira S., Nogueira P., Silva R. (2003) Tributyltin and triphenyltin toxicity on estuarine sediment bacteria. In: Fresenius Environmental Bulletin. 12, 11, 1361-1367.
Correia M., Boavida F., Grosso F., Salgado M.J., Melo Cristino J., Mendo S., Duarte A. (2003) Molecular characterization of a new class 3 integron in Klebsiella pneumoniae. In: Antimicrobial Agents And Chemotherapy. 47, 9, 2838-2843.
Pereira C., Guilherme S., Barroso C., Verschaeve L., Pacheco M., Mendo S. (2010) Evaluation of DNA Damage Induced by Environmental Exposure to Mercury in Liza aurata Using the Comet Assay. In: Archives Of Environmental Contamination And Toxicology. 58, 1, 112-122.
Gonçalves O., Pereira R., Coimbra M.A., Gonçalves F., Mendo S., Rocha S. (2011) Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. In: Mutation Research-genetic Toxicology And Environmental Mutagenesis. 723, 1, 18-25.
Caetano T., Krawczyk J.M., Moesker E., Suessmuth R.D., Mendo S. (2011) Two component lantibiotics biosynthesis in E. coli: licFGEHI immunity genes are not essential for lichenicidin production and self-protection. In: Applied And Environmental Microbiology. 77, 14, 5023-5026.
Lourenço J., Silva A., Carvalho F., Oliveira J., Malta M., Mendo S., Gonçalves F., Pereira R. (2011) Histopathological changes in the earthworm Eisenia andrei associated with the exposure to metals and radionuclides. In: Chemosphere. 85, 1630-1634.
Lourenço J., Pereira R., Silva A., Carvalho F., Oliveira J., Malta M., Paiva A., Gonçalves F., Mendo S. (2012) Evaluation of the sensitivity of genotoxicity and cytotoxicity endpoints in earthworms exposed in situ to uranium mining wastes. In: Ecotoxicology And Environmental Safety. 75, 46-54.
Oldach F., Al-Toma R., Kuthning A., Caetano T., Mendo S., Budisa N., Suessmuth R.D. (2012) Congeneric Lantibiotics from In Vivo Ribosomal Peptide Synthesis with non-canonical Amino Acids. In: Angewandte Chemie - International Edition. 51, 2, 415-418.
Pascoal S. C., Carvalho G., Creer S., Rock J., Kawaii K., Mendo S., Hughes R. (2012) Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments. In: Plos One. 7, 1, e30289
Lourenço J., Pereira R., Gonçalves F., Mendo S. (2013) SSH gene expression profile of Eisenia andrei exposed in situ to a naturally contaminated soil from an abandoned uranium mine. In: Ecotoxicology And Environmental Safety. 88, 16–25
Cruz A., Micaelo N., Félix V., Song J., Kitamura S., Suzuki S., Mendo S. (2013) sugE: a gene involved in tributyltin (TBT) resistance of Aeromonas molluscorum Av27. In: Journal Of General And Applied Microbiology. 59, 1, 39-47.
Lourenço J., Pereira R., Gonçalves F., Mendo S. (2013) Metal bioaccumulation, genotoxicity and gene expression in the European wood mouse (Apodemus sylvaticus) inhabiting an abandoned uranium mining area. In: Science Of The Total Environment. 443, 673–680
Pascoal S., Carvalho G., Vasieva O., Highes R., Cossins A., Fang Y., Ashelford K., Olohan L., Barroso C., Mendo S., Creer S. (2013) Transcriptomics and in vivo tests reveal novel mechanisms underlying endocrine disruption in an ecological sentinel, Nucella lapillus. In: Molecular Ecology. 22, 6, 1589-1608.
Da Rocha E., Rosenthal A., Calado V., Saraiva J., Mendo S. (2009) Byssochlamys nivea inactivation in pineapple juice and nectar using high pressure cycles. In: Journal Of Food Engineering. 95, 4, 664-669.
Lourenço J., Pereira R., Pinto F., Caetano T., Silva A., Carvalheiro T., Guimarães A., Gonçalves F., Paiva A., Mendo S. (2013) Biomonitoring a human population inhabiting nearby a deactivated uranium mine. In: Toxicology. 305, 8, 89-98.
Pinheiro J.N, Marques C.R., Pinto G., Mestiri A., Gomes N.C.M., Mendo S., Gonçalves F., Rocha-Santos T., Duarte A.C., Römbke J., Sousa J.P., Ksibi M., Haddioui A., Pereira R. (2013) The performance of Fraxinus angustifolia as a helper for metal phytoremediation programs and its relation to the endophytic bacterial communities. In: Geoderma. 202, 171-182.
Cruz A., Areias D., Duarte A., Correia A., Suzuki A., Mendo S. (2013) Aeromonas molluscorum Av27 is a potential tributyltin (TBT) bioremediator: phenotypic and genotypic characterization indicates its safe application. In: Antonie Van Leeuwenhoek. 104, 385-396.
Silva P.V., Silva A.R.R, Mendo S., Loureiro S. (2014) Toxicity of tributyltin (TBT) to terrestrial organisms and its species sensitivity distribution. In: Science Of The Total Environment. 466–467, 1037–1046
Cruz A., Moreira R., Mendo S. (2014) An easy, rapid and inexpensive method to monitor tributyltin (TBT) toxicity in the laboratory. In: Folia Microbiologica. 59, 3, 203-207.
Cruz, A., Rodrigues, R., Barroso, C, Mendo, S. (2012) Aeromonas molluscorum Av27 transcriptome analysis: future applications for TBT detection and remediation. In: Febs Journal . 279 , supl. 1, 231-232.
Cruz A., Henriques I., Sousa A.C.A., Baptista I., Almeida A., Takahashi S., Tanabe S., Correia A., Suzuki S., Anselmo A.M., Mendo S. (2014) A microcosm approach to evaluate the degradation of tributyltin (TBT) by Aeromonas molluscorum Av27 in estuarine sediments. In: Environmental Research. 132, 430-437.
Lapuente J, Lourenço J, Mendo S.A., Borràs M., Martins M.G., Costa P.M, Pacheco M. (2015) The Comet Assay and its applications in the field of ecotoxicology: a mature tool that continues to expand its perspectives. In: Frontiers In Genetics. 6, 180,
Caetano T., Barbosa J., Moesker E., Sussmuth R.D., Mendo S. (2014) Bioengineering of lanthipeptides in Escherichia coli: assessing the specificity of lichenicidin and haloduracin biosynthetic machinery. In: Research In Microbiology. 165, 7, 600-604.
Gama S., Rodrigues I., Marques F., Palma E., Correia I., Carvalho M.F.N.N., Pessoa J.C., Cruz A., Mendo S., Santos I.C., Mendes F., Santos I., Paulo A. (2014) New ternary bipyridine-terpyridine copper(II) complexes as self-activating chemical nucleases. In: Rsc Advances. 4, 106, 61363-61377.
Caetano T., Sussmuth R.D., Mendo S. (2015) Impact of Domestication in the Production of the Class II Lanthipeptide Lichenicidin by Bacillus licheniformis I89. In: Current Microbiology. 70, 3, 364-368.
Santos T., Cruz A., Caetano T., Covas C., Mendo S. (2015) Draft genome sequence of Pedobacter sp. strain NL19, a producer of potent antibacterial compounds. . In: Genome Annoucements. 3, 2, e00184-15
Silva A.R.R., Cardoso D.N., Cruz A., Lourenco J., Mendo S., Soares A.M.V.M., Loureiro S. (2015) Ecotoxicity and genotoxicity of a binary combination of triclosan and carbendazim to Daphnia magna. In: Ecotoxicology And Environmental Safety. 115, 279-290.
Santos, C., Caetano, T., Ferreira, S., Mendo, S. (2010) First description of the blaIMP-8 in a Pseudomonas mendocina isolated in Hospital Infante D. Pedro, Aveiro, Portugal. In: Research Of Microbiology. 161, 4, 305-307.
Dias D., Torres R.T., Kronvall G., Fonseca C., Mendo S., Caetano T. (2015) Assessment of antibiotic resistance of Escherichia coli isolates and screening of Salmonella spp. in wild ungulates from Portugal. In: Research In Microbiology. 166, 7, 584-593.
Cruz A., Rodrigues R., Pinheiro M., Mendo S. (2015) Transcriptomes analysis of Aeromonas molluscorum Av27 cells exposed to tributyltin (TBT): Unravelling the effects from the molecular level to the organism. In: Marine Environmental Research. 109, 132-139.
Barbosa J., Caetano T., Mendo S. (2015) Class I and Class II Lanthipeptides Produced by Bacillus spp. In: Journal Of Natural Products. 78, 11, 2850-2866.
Dias L., Caetano T., Pinheiro M., Mendo S. (2015) The lanthipeptides of Bacillus methylotrophicus and their association with genomic islands. In: Systematic And Applied Microbiology. 38, 8, 525-533.
Ofoegbu P.U., Simao F.C.P., Cruz A., Mendo S., Soares A.M.V.M., Pestana J.L.T. (2016) Toxicity of tributyltin (TBT) to the freshwater planarian Schmidtea mediterranea. In: Chemosphere. 148, 61-67.
Pavlaki M.D., Araujo M.J., Cardoso D.N., Silva A.R.R., Cruz A., Mendo S., Soares A.M.V.M., Calado R., Loureiro S. (2016) Ecotoxicity and genotoxicity of cadmium in different marine trophic levels. In: Environmental Pollution. 215, 203-212.
Lourenco J., Mendo S., Pereira R. (2016) Radioactively contaminated areas: Bioindicator species and biomarkers of effect in an early warning scheme for a preliminary risk assessment. In: Journal Of Hazardous Materials. 317, 503-542.
Silva A.R.R., Cardoso D.N., Cruz A., Pestana J.L.T., Mendo S., Soares A.M.V.M., Loureiro S. (2017) Multigenerational effects of carbendazim in Daphnia magna. In: Environmental Toxicology And Chemistry. 36, 2, 383-394.
Cruz A., Anselmo A.M., Suzuki S., Mendo S. (2015) Tributyltin (TBT): A Review on Microbial Resistance and Degradation. In: Critical Reviews In Environmental Science And Technology. 45, 9, 970-1006.
Santos C., Ramalheira E., Da Silva G., Mendo S. (2017) Genetically unrelated multidrug- and carbapenem-resistant Citrobacter freundii detected in outpatients admitted to a Portuguese hospital. In: Journal Of Global Antimicrobial Resistance. 8, 18-22.
Covas C., Caetano T., Cruz A., Santos T., Dias L., Klein G., Abdulmawjood A., Rodriguez-Alcala L.M., Pimentel L.L., Gomes A., Freitas A.C., Garcia-Serrano A., Fontecha J., Mendo S. (2017) Pedobacter lusitanus sp nov., isolated from sludge of a deactivated uranium mine. In: International Journal Of Systematic And Evolutionary Microbiology. 67, 5, 1339-1348.
Correia B., Lourenco J., Marques S., Nogueira V., Gavina A., Rasteiro M.D., Antunes F., Mendo S., Pereira R. (2017) Oxidative stress and genotoxicity of an organic and an inorganic nanomaterial to Eisenia andrei: SDS/DDAB nano -vesicles and titanium silicon oxide. In: Ecotoxicology And Environmental Safety. 140, 198-205.
Cardoso D.N., Silva A.R.R., Cruz A., Lourenco J., Neves J., Malheiro C., Mendo S., Soares A.M.V.M., Loureiro S. (2017) THE COMET ASSAY IN FOLSOMIA CANDIDA: A SUITABLE APPROACH TO ASSESS GENOTOXICITY IN COLLEMBOLANS. In: Environmental Toxicology And Chemistry. 36, 9, 2514-2520.
Rodrigues R., Lourenco J., Pereira P., Carvalho S., Mendo S. (2017) Effects of metal contamination on the gene expression profile of two benthic species: Cerastoderma edule and Ruditapes philippinarum. In: Marine Pollution Bulletin. 125, 1-2, 157-165.
Lourenco J., Marques S., Carvalho F.P., Oliveira J., Malta M., Santos M., Goncalves F., Pereira R., Mendo S. (2017) Uranium mining wastes: The use of the Fish Embryo Acute Toxicity Test (FET) test to evaluate toxicity and risk of environmental discharge. In: Science Of The Total Environment. 605, 391-404.
Reis P., Lourenco J., Carvalho F.P., Oliveira J., Malta M., Mendo S., Pereira R. (2018) RIBE at an inter-organismic level: A study on genotoxic effects in Daphnia magna exposed to waterborne uranium and a uranium mine effluent. In: Aquatic Toxicology. 198, 206-214.
Reis P., Pereira R., Carvalho F. P., Oliveira J., Malta M., Mendo S., Lourenço J. (in press) Life history traits and genotoxic effects on Daphnia magna exposed to waterborne uranium and to a uranium mine effluent - a transgenerational study. In: Aquatic Toxicology.
Other Papers (1)
Cruz A, Caetano T, Suzuki S, Mendo S (2008) Corrigendum to “Aeromonas veronii, a tributyltin (TBT)-degrading bacterium isolated from an estuarine environment, Ria de Aveiro in Portugal” [Mar. Environ. Res. 64 (2007) 639–650]. In: Marine Environmental Research. 66, 2, 309
Books (2)
Hamamura N., Suzuki S., Mendo S., Barroso C., Iwata H., Tanabe S. (2010) Biological Responses to Chemical Contaminants: from Molecular to Community Level. In: Interdisciplinary Studies on Environmental Chemistry. (EDS.), Tokyo. TERRAPUB. 3, 978-4-88704-152-3.
António Corrreia, Sónia Mendo (2001) Genética Exercícios Teórico-Práticos e Práticos. In: Aveiro. Universidade de Aveiro.
Book Chapter (2)
Torres RT ., Cunha M ., Caetano T ., Mendo S ., Serrano E ., Fonseca C . (2017) Ecology, Conservation and Management of Wild Pigs and Peccaries . In: Melletti M; Meijaard E. (EDS.), Cambridge. Cambridge University Press. 97811071873133.
Lourenço J., Mendo S., Pereira R. (2019) Remediation Measures for Radioactively Contaminated Areas. In: Gupta D.K., Voronina A.. (EDS.), Cham. Springer. 163-200.
Thesis (17)
Cruz A. (2005) Identificação e clonagem dos genes implicados na resistência ao tributilestanho em bactérias marinhas. In: MSc Thesis.
Pascoal Sonia C.M. (2011) Nucella lapillus: imposex transcriptome analysis and phenotypic plasticity. In: PhD Thesis.
Ferreira S. (2010) ISCR elements and their association with antibiotic resistance genes. In: PhD Thesis.
Caetano T. (2011) Lichenicidin biosynthesis and search for novel antibacterial peptides. In: PhD Thesis.
Nogueira P. (2009) Biomarcadores moleculares em peixes expostos a xenobióticos. In: PhD Thesis.
Cruz A. (2012) Tributyltin (TBT) resistance in Aeromonas molluscorum Av27. In: PhD Thesis.
Barbosa J. (2012) Lichenicidin: Regulation, Expression and bioengineering in E. coli. In: MSc Thesis.
Lourenço J.I.V.L. (2012) Evaluation of genotoxic effects in humans and bioindicator species from an abandoned uranium mine area. In: PhD Thesis.
Rodrigues R.S.M. (2013) Transcriptome analysis of Aeromonas molluscorum Av27 following TBT exposure. In: MSc Thesis.
Dias L.A. (2013) Search for new lantibiotics. In: MSc Thesis.
Silva, A. R. R. G. (2011) Toxicity and bioremediation evalution of TBT: bioassays with plants. In: MSc Thesis.
Dias D. (2014) Presence of pathogenic bacteria and antimicrobial resistance in Portuguese wild ungulates. In: MSc Thesis.
Pereira M. (2014) Directed evolution of lichenicidin. In: MSc Thesis.
Silva, P. V. (2011) TBT toxicity and bioremediation in soils: bioassays with invertebrates. In: MSc Thesis.
Ferreira S. (em curso) Elementos CR e a sua associação a genes de resistência. In: PhD Thesis.
Santos, Tiago Filipe Melo (2015) Bioinformatics analysis of the Pedobacter sp. NL19 genome. In: MSc Thesis.
Coito, Ana Margarida Barros do (2015) Bacterial communities and antibiotic resistance genes in hospital effluents and municipal wastewaters of Aveiro. In: MSc Thesis.
Communications (105)
Cruz A., Nonaka L., Domingos A., Suzuki S., Mendo S. (2006) Tributyltin (TBT) resistance in Aeromonas veronii: Isolation of gene(s) and protein(s) involved in TBT resistance. In:
Cruz A., Caetano T., Mendo S. (2005) Mechanisms involved in resistance/tolerance to TBT and other antifouling compounds by marine bacteria. In:
Sousa A.C., Mendo S., Barroso C.M. (2006) Comparison of the acute toxicity of copper and tributyltin (TBT) to veliger larvae of Nassarius reticulatus. In:
Sousa A., Mendo S., Barroso C.M. (2005) Imposex and organotin contamination in Nassarius reticulatus (L.) along the portuguese coast. In:
Sousa A., Génio L., Mendo S., Barroso C.M. (2005) Acute toxicity of tributyltin (TBT) to veliger larvae of Nassarius reticulatus. In:
Lourenço J., Castro B.B., Machado R., Mendo S., Gonçalves F., Pereira R. (2008) Assessment of uranium genotoxicity by comet assay in the teleost fish Carassius auratus. In:
Caetano T., Leal P. M., Mendo S. (2008) Novel antistaphylococcal peptide produced by Bacillus licheniformis. In:
Caetano T., Ferreira S., Tortas L., Cerveira F., Ramalheira E., Mendo S. (2008) Prevalence of In99 among Pseudomonas aeruginosa isolates from a central region of Portugal (Aveiro) since 2003. In:
Caetano T., Howe R.A., Hawrani A., Dempsey C., Mendo S., Walsh T.R. (2008) Comparison of RTA3 and Colistin for Selection and Stability of Resistant Mutants with Clinical and Type Strains of Pseudomonas, Acinetobacter, and Escherichia Coli. In:
Caetano T., Howe R.A., Hawrani A., Dempsey C., Mendo S., Walsh T.R. (2008) Activity of RTA-3 Against Multi-Drug Resistant Pseudomonas, Acinetobacter and Enterobacteriaceae Possessing Defined Genotypes. In:
Cruz A., Suzuki S., Mendo S. (2008) Different genes coding for tributyltin (TBT) resistance in Aeromonas spp. In:
Cruz A., Nonaka L., Suzuki S., Mendo S. (2007) Aeromonas veronii, tributyltin (TBT) resistant bacteria: future development of a biosensor for TBT detection and bioremediation. In:
Santos C, Caetano T, Ramalheira E, Ferreira S, Mendo S (2009) Occurrence and characterization of class 1 integrons from isolates collected in a hospital’s sanitary facility in Aveiro, Portugal. In:
Lourenço J., Pereira R., Silva A. C., Morgado J. M., Carvalho F., Oliveira J., Malta M., Paiva A., Mendo S., Gonçalves F. (2009) New Genotoxic Endpoints for the Earthworm Reproduction Assay. In:
Lourenço J., Pereira R., Silva A. C., Morgado J. M., Carvalho F., Oliveira J., Malta M., Paiva A., Mendo S., Gonçalves F. (2010) Measurement of Genotoxicity Endpoints in the Earthworm Reproduction Assay. In:
Ferreira S., Mendo S. (2004) Molecular genotyping of Pseudomonas aeruginosa clinical isolates resistant to quinolones: detection of mutations in the gyr genes. In:
Ferreira S., Walsh T.R., Mendo S. (2005) Novel gyrB and parE mutations detected in the quinolone-resistance-determining-region of clinical quinolone resistant Pseudomonas aeruginosa. In:
Ferreira S., Ferreira S., Toleman M. A. , Toleman M., Walsh T.R., Walsh T., Mendo S., Mendo S. (2007) Occurrence and diversity of genetic resistance determinants among Enterobacteriaceae clinical isolates in Aveiro, Portugal. In:
Ferreira S., Walsh T.R., Mendo S. (2007) Outbreak of a nosocomial carbapenem resistant Acinetobacter baumannii in Aveiro, Portugal. In:
Ferreira S., Ramalheira E., Mendo S. (2007) Bactérias multirresistentes: um problema crescente?. In:
Ferreira S., Pereira A., Paradela A., Tortas L., Mendo S., Ramalheira E. (2007) Diagnóstico da tuberculose: métodos moleculares. In:
Pereira A., Ferreira S., Paradela A., Cerveira F., Ramalheira E., Mendo S. (2008) First report of plasmid-mediated quinolone resistance determinants qnrA, qnrB and qnrS among Gram-negative clinical isolates from Aveiro, Portugal. In:
Pereira A., Ferreira S., Paradela A., Cerveira F., Ramalheira E., Mendo S. (2008) Prevalence of In99 among Pseudomonas aeruginosa isolates from a central region of Portugal (Aveiro) since 2003. In:
Ferreira S., Paradela A., Ramalheira E., Walsh T.R., Mendo S. (2008) First description of a Klebsiella pneumoniae carrying both qnrA and qnrB genes in Aveiro, Portugal. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Ocurrence of blaCTX-M-15 gene in multidrug-resistant Citrobacter freundii. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) First description of a multidrug-resistant Citrobacter freundii carrying both qnrA and qnrB in Aveiro, Portugal. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Prevalence of ampC β-lactamase genes in Enterobacteriaceae clinical isolates from Aveiro, Portugal. In:
Cruz A., Suzuki S., Mendo S. (2008) Aeromonas veronii, a TBT degrading bacterium isolated from an estuarine environment, Ria de Aveiro in Portugal. In:
Pereira R., Ksibi M., Haddioui A., Römbke J. , Sousa J.P. , Gonçalves F., Marques C., Frankenbach S., Silva C., Mistiri A. , Hentati O. , Gomes N., Mendo S. (2010) Research on bioremediation of mining areas as part of a NATO Science for Peace Project. In:
Lourenço J., Pereira R., Silva A., Carvalho F., Oliveira J., Malta M., Paiva A., Gonçalves F., Mendo S. (2011) In situ and laboratorial assays using earthworms for the risk assessment of uranium mines. In:
Santos C., Caetano T., Ramalheira H., Ferreira S., Mendo S. (2010) Occurrence and dissemination of genetic resistance determinants among Gram-negative isolates collected from inanimate surfaces in a hospital in Aveiro, Portugal. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Mendo S. (2009) Prevalence of ampC b-lactamase genes in Enterobacteriaceae clinical isolates from Aveiro, Portugal. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Mendo S. (2009) First description of a multidrug-resistant Citrobacter freundii carrying both qnrA and qnrB in Aveiro, Portugal. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T., Mendo S. (2009) Ocurrence of blaCTX-M-15 gene in multidrug-resistant Citrobacter freundii. In:
Ferreira S., Mendo S. (2005) Molecular genotyping as a tool for identifying dissemination of quinolone resistant Pseudomonas aeruginosa isolates. In:
Pereira S., Domingues S., Mendo S., Duarte A., da Silva G (2008) Occurrence and molecular characterization of Class 1 integrons in Acinetobacter baumanii clinical isolates collected from 2005 to 2006 in Portugal. In:
Barroso C.M., Mendo S. (2005) History of organotin pollution in Portuguese coastal waters: analysis of exposure potential, biological effects and future Ecological Risk Assessment approach. In:
A. Paradela, S. Ferreira, E. Ramalheira, S. Mendo (2010) Evaluation of phenotypic methods for detection of AmpC producers among Klebsiella pnemoniae clinical isolates. In:
Ferreira S., Santos, C., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of class 1 integrons in Klebsiella pneumoniae Isolates in a hospital in Aveiro, central Portugal. In:
Ferreira S., Tortas L., Ramalheira E., Mendo S. (2010) Surveillance of Pseudomonas aeruginosa isolates resistant to carbapenems during 7 years period (2003-2009) in Aveiro. In:
Diaz R., Ferreira S., Freitas S., Mendo S. (2010) Prevalence of sul genes in E.coli causing urinary tract infections in the community. In:
Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of genetic resistant determinants among Gram negative isolates collected form inanimate surfaces in the hospital Infante D. Pedro Aveiro, central Portugal. In:
Lourenço J., Pereira R., Silva A., Carvalho F., Oliveira J., Malta M., Paiva A., Gonçalves F., Mendo S. (2011) Earthworms’ in situ exposure and evaluation of genotoxicity endpoints to assess the toxicity of uranium mining wastes. In:
Pascoal S., Queiroga H., Mendo S. (2006) Development and application of microsatellites as a tool to study Carcinus maenas genetic flow along the Portuguese coast. In:
Pascoal S., Creer S. , Hughes R., Miguez C., Mendo S., Carvalho G. (2008) Environmental genomics of the marine gastropod Nucella lapillus in response to organotin pollution. In:
Pascoal S., Carvalho G., Hughes R., Cossins A., Ashelford K., Olohan L., Fang Y., Barroso C., Mendo S., Creer S. (2010) Environmental genomics of the marine gastropod Nucella lapillus in response to organotin pollution. In:
Caetano T., Faria R., Oldach F., Suessmuth R.D., Mendo S. (2012) LicP proteolysis of the two-component lantibiotic lichenicidin using heterologous expression in Escherichia coli. In:
Silva, P.M.P.V., Silva, A.R.R., Cruz, A., Mendo, S., Loureiro, S. (2012) Tributyltin (TBT) bioremediation evaluation in soil after Aeromonas molluscorum Av27 inoculation. In:
Lourenço J., Pereira R., Gonçalves F., Mendo S. (2012) SSH gene expression profile of Eisenia andrei exposed in situ to a naturally contaminated soil from an abandoned uranium mine (Oral presentation). In:
Lourenço J., Pereira R., Pinto F., Caetano T., Silva A., Carvalheiro T., Guimarães A., Gonçalves F., Paiva A., Mendo S. (2013) Genotoxicity and immunotoxicity in a human population inhabiting nearby a deactivated uranium mine (Poster presentation). In:
Santos, C., Ramalheira, E., Mendo, S. (2012) KPC-3 produced by Klebsiella spp. isolated from inanimate hospital surfaces in Aveiro, Central Portugal. In:
Santos, C., Ramalheira, E., Mendo, S. (2012) Prevalence of integrons in inanimate surfaces within Hospital Infante D. Pedro, Aveiro, Central Portugal. In:
Cruz A., Henriques I., Sousa A., Baptista I., Anselmo A. M., Almeida A., Takahashi S., Tanabe S., Correia A., Suzuki S., Mendo S. (2012) Bioremediation of tributyltin (TBT) by Aeromonas molluscorum Av27. In:
Silva P.V., Silva A.R.R., Mendo S., Loureiro S. (2013) Species sensitivity distribution of tributyltin (TBT) on terrestrial organisms. In:
Caetano T., Suessmuth R.D., Mendo S. (2013) Insights into the lichenicidin self-protection mechanism using E. coli as model organism. In:
Oldach F, Caetano T., Kuthning A., Al Toma R., Krawczyk J.M., Mosker E., Budisa N., Mendo S., Suessmuth R.D. (2012) Heterologous Expression of the Lantibiotic Lichenicidin in E.coli and generation of new congeners by introducing non-natural amino acids. In:
Cruz A., Rodrigues R., Barroso C., Suzuki S., Mendo S. (2012) Aeromonas molluscorum Av27 transcriptome analysis: future applications for TBT detection and remediation. In:
Barbosa J., Caetano T., Suessmuth R.D., Mendo S. (2013) Heterologous expression of lichenicidin: improvement of the biosynthesis levels in E. coli. In:
Barbosa J., Caetano T., Suessmuth R.D., Mendo S. (2013) Directed evolution of the lantibiotic lichenicidin. In:
Caetano T., Barbosa J., Cruzeiro J., Suessmuth, R.D., Mendo, S. (2013) Random mutagenesis of the lantibiotic linchenicidin in E. coli. In:
Covas C., Rodrigues R., Covas C., Cruz A., Cruz A., Cruz A., Suzuki S., Lourenço J., Lourenço J., Pereira R., Pereira R., Mendo S. , Caetano T., Caetano T., Mendo S., Mendo S. (2013) Search for novel bioactive compounds from extreme environments: biotechnological potential of two bacterial strains isolated from Portuguese abandoned uranium mine sediments. In:
Covas C., Cruz A., Lourenco J., Pereira R., Caetano T., Mendo S. (2013) Search for novel bioactive compounds from extreme environments: biotechnological potential of two bacterial strains isolated from Portuguese abandoned uranium mine sediments. In:
Cruz A., Henriques I., Sousa A., Correia A., Suzuki A., Anselmo, A., Mendo, S. (2013) A microcosm approach shows that Aeromonas molluscorum Av27 enhances the degradation of tributyltin (TBT) in an estuarine sediment. In:
Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2013) Evolution of the resistance profile in non-clonal Pseudomonas aeruginosa. In:
Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2013) Dissemination of carbapenem-resistant Pseudomonas aeruginosa in Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. In:
Santos C., Caetano T., Viana A., Silva A., Mendo S. (2013) Emerging of colistin-resistant Acinetobacter spp. isolates in Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal. In:
Dias L., Caetano T., Marques C., Pereira R., Mendo S. (2013) Bacillus amyloliquefaciens SMA1 isolated from an heavy metal contaminated environment produces Anti-Gram-negative compounds. In:
Silva A.R.R., Cardoso D.N., Cruz A., Lourenço J., Mendo S., Soares A. Loureiro S. (2014) Binary mixture toxicity of triclosan and carbendazim on Daphnia magna. In:
Silva, A.R.R., Silva, P.M.P.V., Mendo, S., Loureiro, S., (2012) Toxicity of Tributyltin (TBT) on terrestrial invertebrates and plants. In:
Torres R., Dias D., Caetano T., Mendo S., Fonseca C. (2014) Antimicrobial resistance in wild boar (Sus scrofa) in Portugal. In:
Dias D., Torres R., Fonseca C., Mendo S., Caetano T. (2014) Assessment of antibacterial resistance levels and presence of pathogenic bacteria in Portuguese wild ungulates. In:
Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Mobile genetic elements: a comparative study of their presence in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal, in 2005 and 2008. In:
Lourenço J., Marques S., Vala H., Esteves F., Carvalho F., Pereira R., Mendo S. (2014) Histopathological evaluation of farm animals living near a uranium mine as sentinels of human’s exposure and health hazards. In:
Correia B., Lourenço J., Marques S., Mendo S., Pereira R. (2014) Genotoxic effect and antioxidant response to titanium silicon oxide in Eisenia andrei. In:
Pereira R., Correia B., Lourenço J., Marques S., Mendo S., Antunes F. (2015) Evaluation of the genotoxicity effect and antioxidant response of two nanomaterials (TiSiO4 and nanovesicles of SDS/DDAB) in Eisenia andrei. In:
Santos, C. Viana, A. Silva, A. Mendo, S. (2014) Prevalence of colistin-resistant Acinetobacter spp. isolates in Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal. In:
Santos C., Lima C, Ramalheira E., Caetano T., Mendo S. (2011) Tracking the presence of class 1 integrons in Gram-negative bacteria collected from surfaces and biological samples in Hospital Infante D. Pedro, Aveiro, central Portugal. In:
Santos, C. Diaz, R. Ramalheira, E. Mendo, S. (2011) Antibiotic resistance genes detected in Enterobacteriaceae that colonize inanimate surfaces. In:
Santos, C. Ramalheira, E. Caetano, T. Mendo, S. (2011) In37 – a complex class 1 integron found in different species from hospital surfaces / furniture. In:
Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Prevalence of beta-lactamase enzymes in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal. In:
Santos, C. Da Silva, G. Mendo, S. (2013) Dissemination of multidrug resistant Gram-negative bacteria within the hospital environment. In:
Santos, C. Ramalheira, E. Mendo, S. (2013) Emergence of carbapenem resistance among Gram-negative bacteria within Centro Hospitalar do Baixo Vouga, Aveiro. In:
Santos, C. Ferreira, S. Ramalheira, R. Da Silva, G. Mendo, S. (2014) Carbapenem-resistant Pseudomonas aeruginosa disseminated in Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. In:
Silva A.R.R., Cardoso D.N., Cruz A., Mendo S., Soares A.M.V.M. .a.n.d. .L.o.u.r.e.i.r.o. (2015) Effects of an environmental relevant concentration of carbendazim on twelve generations of Daphnia magna . In:
Dias D., Torres R., Fonseca C., Mendo S., Caetano T. (2015) Identification of Shiga toxin-producing E. coli (STEC) in Portuguese wild ungulates. In:
Dias L., Caetano T., Pinheiro M., Mendo S. (2015) The lanthipeptides of B. methylotrophicus are associated with genomic islands. In:
Barbosa J., Caetano T., Mendo S. (2015) Lichenicidin directed mutagenesis: how changes in charged amino acids affect bioactivity. In:
Santos T., Caetano T., Mendo S. (2015) Bioinformatic analysis of the Pedobacter sp. NL19 genome. In:
Covas C., Caetano T., Cruz A., Mendo S. (2015) Biotechnological potential of Pedobacter portucalensis NL19 sp. nov., isolated from an abandoned uranium mine in Portugal. In:
Barbosa J., Cruzeiro J., Süssmuth R., Caetano T., Mendo S. (2012) Lichenicidin Bioengineering: peptides with changed bioactivity. In:
Barbosa J., Caetano T., Süssmuth R., Mendo S. (2013) Lichenicidin production: construction of expression systems. In:
Caetano T., Barbosa J., Cruzeiro J., Jorge R., Süssmuth R., Mendo S. (2012) Search for new lantibiotics: case study of lichenicidin. In:
Barbosa J., Caetano T., Süssmuth R., Mendo S. (2012) Lichenicidin: heterologous expression and biosynthesis comparison. In:
Mendo, Sonia Transcriptomes analysis of Aeromonas molluscorum Av27 cells exposed to tributyltin (TBT): unravelling the effects from the molecular level to the organism. In:
Vaz A., Pereira R., Marques S., Carvalho F. P., Malta M., Oliveira J., Mendo S., Lourenço J. (2017) Uranium mining legacy sites: genetic effects of metals and low-dose radiation in farm animals exposed to contaminated water and foodstuffs. In:
Lourenço J., Marques S., Carvalho F.P., Oliveira J., Malta M., Santos M., Gonçalves F., Pereira R., Mendo S. (2017) Uranium mining wastes: The use of the Fish Embryo Acute Toxicity Test (FET) test to evaluate toxicity and risk of environmental discharge. In:
Reis P., Lourenço J., Mendo S., Carvalho F. P., Oliveira J., Malta M., Pereira R. (2017) RIBE Assessed At An Inter-organismic Level in Daphnia magna Exposed To Low Doses Of Uranium Mine Effluent And Waterborne Uranium. In:
Reis P., Lourenço J., Mendo S., Carvalho F. P., Oliveira J., Malta M., Pereira R. (2017) Long-term Effects on DNA Integrity and Population Parameters Of Daphnia magna Exposed To Low 5 Doses Of A Uranium Mine Effluent And Waterborne Uranium. In:
Joana Barbosa, Tânia Caetano, Eva Mösker, Roderich Süssmuth and Sónia Mendo (2017) Lichenicidin directed mutagenesis: Ser and Thr interchangeability in ring formation. In:
D. Dias, R. Torres, G. Kronvall, C. Fonseca, S. Mendo, T. Caetano (2015) Presence of pathogenic bacteria and antibiotic resistance in Portuguese wild ungulates. In:
Viana, AT., Covas C., Santos T., Mendo S., Caetano T (2017) Antibiotic and metal(loid) tolerance of Pedobacter lusitanus and closely-related species. In:
Almeida, B., Covas C., Esteves A.C., Alves A., Domingues P., Caetano T., Mendo S. (2017) Growth media effect on the production of pedopeptins by the newly described species Pedobacter lusitanus NL19. In:
Costa H., Osorio H., Allers T., Mendo S., Caetano T. (2017) Lanthipeptides of Archaea: the case study of Haloferax mediterranei. In:
Caetano T., Faria R., Oldach F., Suessmuth R.D., Mendo S. (2011) Protease specificity in the biosynthesis of a two-component lantibiotic. In:
Ana Rita R. Silva, Cátia Santos, Nuno G. C. Ferreira, Rui Morgado, Diogo N. Cardoso, Andreia Cruz, Sónia Mendo, Amadeu M. V. M. Soares and Susana Loureiro (2018) From mother to offspring: multigenerational effects of carbendazim at individual and subcellular levels in Daphnia magna. In:
Other Publications (24)
Lourenço J., Pereira R., Silva A. C., Morgado J. M., Oliveira J., Carvalho F., Malta M., Paiva A., Mendo S., Gonçalves F. (2010) Measurement of Genotoxic Endpoints in Earthworms Exposed to Radioactive Wastes from an Abandoned Uranium Mine. Interdisciplinary Studies on Environmental Chemistry — Biological Responses to Contaminants, 2 - 4 September 2009, Aveiro, Portugal (Proceedings) in Interdisciplinary Studies on Environmental Chemistry — Biological Responses to Contaminants pp 219-225. In:
Cruz A., Henriques I., Correia A., Suzuki S., Mendo S. (2010) Aeromonas molluscorum Av27: A Potential Natural Tool for TBT Decontamination. Proceeding in Interdisciplinary Studies on Environmental Chemistry — Biological Responses to Contaminants, September 2-4th. Aveiro, Portugal. In:
Cruz A., Nonaka L., Suzuki S., Mendo S. (2007) Aeromonas veronii, tributyltin (TBT) resistant bacteria: future development of a biosensor for TBT detection and bioremediation. Proceeding in XIII Symposium in Pesticide Chemistry, September 3-6th. Piacenza, Italy. pp. 807-811. In:
Cruz A., Nonaka L., Domingos A., Suzuki S., Mendo S. (2010) Tributyltin (TBT) resistance in Aeromonas veronii: Isolation of gene(s) and protein(s) involved in TBT resistance. Proceeding in Coastal Marine Environmental Research, November 17-19th. Matsuyama, Japan. In:
Ferreira S., Paradela A., Ribau A., Ramalheira E., Mendo S. (2007) Detection of extended-spectrum beta-lactamases, including the CTX-M-type enzymes, among Enterobacteriaceae using VITEK 2 system and the Advanced Expert System. Proceeding in Supplement to Clinical Microbiology and Infection Vol.13, Suppl. 1. In:
Ferreira S., Toleman M. A., Walsh T.R., Mendo S. (2007) “Occurrence and diversity of genetic resistance determinants among Enterobacteriaceae clinical isolates in Aveiro, Portugal. Proceeding in Supplement to Clinical Microbiology and Infection Vol.13, Suppl. 1. In:
Caetano T., Ferreira S., Tortas L., Cerveira F., Ramalheira E., Mendo S. (2008) Prevalence of In99 among Pseudomonas aeruginosa isolates from a central region of Portugal (Aveiro) since 2003. Proceeding in Supplement to Clinical Microbiology and Infection Vol.14, Suppl. 7. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Ocurrence of blaCTX-M-15 gene in multidrug-resistant Citrobacter freundii. Proceeding in Supplement to Clinical Microbiology and Infection Vol 15, Suppl. 4. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) First description of a multidrug-resistant Citrobacter freundii carrying both qnrA and qnrB in Aveiro, Portugal. Proceeding in Supplement to Clinical Microbiology and Infection, Vol 15, Suppl. 4. In:
Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Prevalence of ampC β-lactamase genes in Enterobacteriaceae clinical isolates from Aveiro, Portugal. 2009. Proceeding in Clinical Microbiology and Infection, Vol 15, Suppl. 4. In:
Ferreira S., Santos C., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of class 1 integrons in Klebsiella pneumoniae Isolates in a hospital in Aveiro, central Portugal-Clinical Microbiology and Infection vol16, Suppl2. In:
Ferreira S., Santos C., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of class 1 integrons in Klebsiella pneumoniae Isolates in a hospital in Aveiro, central Portugal. 2010. Clinical Microbiology and Infection vol16, Suppl2. In:
Ferreira S., Tortas, L., Ramalheira E., Mendo S. (2010) Surveillance of Pseudomonas aeruginosa isolates resistant to carbapenems during 7 years period (2003-2009) in Aveiro. 2010. Clinical Microbiology and Infection vol16, Suppl.2. In:
Diaz R., Ferreira S., Freitas A., Mendo S. (2010) Prevalence of sul genes in Escherichia coli causing urinary tract infections in the community. Clinical Microbiology and Infection vol16, Suppl2. In:
Paradela A., Ferreira S., Ramalheira E. , Mendo S. (2010) Evaluation of phenotypic methods for detection of AmpC producers among Klebsiella pneumoniae clinical isolates; Clinical Microbiology and Infection vol16, Suppl2. In:
Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of genetic resistance determinants among Gram negative isolates collected from inanimate surfaces in the Hospital Infante D. Pedro, Aveiro, central Portugal; Clinical Microbiology and Infection vol16, Suppl2. In:
Santos C., Caetano T., Ramalheira R., Ferreira S., Mendo S. (2009) Occurrence and characterization of class 1 integrons from isolates collected in a hospital’s sanitary facility in Aveiro, Portugal; Clinical Microbiology and Infection vol15, Suppl3, Page S425. In:
Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Prevalence of beta-lactamase enzymes in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal; Clinical Microbiology and Infection, vol. 17, suppl. 4, page S142. In:
Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Mobile genetic elements: a comparative study of their presence in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal, in 2005 and 2008; Clinical Microbiology and Infection, vol. 17, suppl. 4, page S. In:
Lourenço J., Silva A., Carvalho F., Oliveira J., Malta M., Mendo S., Gonçalves F., Pereira R. (2011) Are histopathological endpoints useful for the evaluation of natural soils contaminated by metals and radionuclides? Toxicol Lett 205 (Supplement 1):S131-S131. In:
Lourenco, J., Marques, S., Vala, H., Esteves, F., Carvalho, F., Pereira, R., Mendo, S. (2014) Histopathological evaluation of farm animals living near a uranium mine as sentinels of human’s exposure and health hazards , in: VIRCHOWS ARCHIV. SPRINGER 233 SPRING ST, NEW YORK, NY 10013 USA, pp. S284–S284. In:
Correia, B., Lourenço, J., Marques, S., Mendo, S., Pereira, R. (2014) Genotoxic effect and antioxidant response to titanium silicon oxide in Eisenia andrei. Toxicol. Lett. 229, Supplement, S201. . In:
Santos, C. Ramalheira, R. Da Silva, G. Mendo, S. (2014) Colonization of the hospital environment by multidrug resistant Gram-negative bacteria. In:
D. Dias, R. Torres, C. Fonseca, S. Mendo, T. Caetano Presença de bactérias patogénicas e resistência antimicrobiana em ungulados selvagens Portugueses; Revista CAPTAR. In:

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