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Cláudia Oliveira

Cláudia Oliveira

Invited Assistant Professor

  • Department: Biology Department
  • Research Group: Stress Biology
  • ISI Web of KnowledgeSM search factor : RID=A-7859-2012


Research Projects

2010-2013: "SEAGULL - Identification of nonpoint sources of faecal pollution in a natural environment: contributing data for risk assessment" (PTDC/AAC-AMB/109155/2008). Principal Investigator: Anabela Pereira, University of Aveiro.


2005-2008: "Assessing conformational stability of aspartic proteinases with biotechnological and medical relevance - Unfolding/refolding of dimeric and monomeric proteins" (POCI/QUI/60791/2004). Principal Investigator: Marlene Barros, Portuguese Catholic University.


1999-2001: "How do Organic Solvents Affect Cardosin A and Cardosin B Activity and Structure. The use of Cardosins in New Strategies and New Tactics for Routine Peptide Synthesis" (Praxis/P/Qui/10131/98). Principal Investigator: Marlene Barros, University of Aveiro.

Academic degrees

BSc in Biology, University of Aveiro, 1997 MSc in Molecular Microbiology, University of Aveiro, 2001 PhD in Biology, University of Aveiro, 2007 Post Doc in Molecular Microbiology, University of Aveiro (SFRH/BPD/65820/2009) - March 2010-February 2013 Molecular Microbiology Lab http://biomicrolab.web.ua.pt/

Research interests

Experience in


Protein purification; Protein stability; Molecular microbiology


Research interests


Plasmid mediated gene transfer in environmental samples; Plasmid roles in microbial communities adaptation; Variability of plasmid associated genetic features.


Other interests


Antimicrobial activity determinations of natural and synthetic composites.

Scientific Supervision

In progress
Concluded

Projects

In progress
Concluded
  • Impact of phytoremediation processes on bacterial communities from Pb and Cd contaminated soils See more
  • GEMOVE: Genes in motion: Mobile genes in microbial communities, how to catch them? See more
  • PhytoMarsh - The phytosphere of salt-marsh plants: an underexplored microbial hot-spot See more
  • SEAGULL- Identification of nonpoint sources of faecal pollution in a natural environment: contributing data for risk assessment See more
  • Assessing conformational stability of aspartic proteinases with biotechnological and medical relevance – Unfolding/refolding of dimeric and monomeric proteins See more

Publications

WoS Papers (18)
Sarmento AC, Oliveira CS, Duarte AS, Pires E, Barros MT (2006) Evaluation of cardosin A as a probe for limited proteolysis in non-aqueous environments - complex substrates hydrolysis. In: Enzyme And Microbial Technology. 38, 3/4, 415-421.
Shnyrova A.V., Oliveira C.S., Sarmento A.C., Barros M.T., Zhadan G.G., Roig M.G., Shnyrov V.L. (2006) Effect of acetonitrile on Cynara cardunculus L. cardosin A stability. In: Int J Biol Macromol. 39, 4-5, 273-9.
Sarmento A.C., Oliveira C.S., Pires E.M., Halling P.J., Barros M.T. (2004) Evaluation of cardosin A as a proteolytic probe in the presence of organic solvents. In: Journal Of Molecular Catalysis B: Enzymatic. . 31, 4-6, 137-141.
Sarmento A.C., Oliveira C.S., Pires E.M., Amado F, Barros M.T. (2004) Reverse hydrolysis by cardosin A. Specificity considerations. In: Journal Of Molecular Catalysis B: Enzymatic.. 28, 1, 33-37.
Sarmento A.C., Oliveira C.S., Pires E.M., Halling P.J., Barros M.T. (2003) Cardosin A as a model aspartic proteinase for the study of organic solvent effects. I. An overview on catalytic and structural aspects. In: Journal Of Molecular Catalysis. B: Enzymatic. 21, 1-2, 19-23.
Pina D.G., Oliveira C.S., Sarmento A.C., Barros M.T., Pires E.M., Zhadan G.G., Villar E., Gavilanes F., Shnyrov V.L (2003) Thermostability of cardosin A from Cynara cardunculus L. In: Thermochimica Acta. 71218, 1-12.
Sarmento A.C., Oliveira C.S., Pereira A.O., Esteves V.I., Moir A.J.G., Saraiva J., Pires E., Barros M. (2009) Unfolding of cardosin A in organic solvents and detection of intermediaries. In: Journal Of Molecular Catalysis B: Enzymatic. 57, 115-122.
Cardoso T., Oliveira C., Sarmento A.C., Pereira A., Nutley M.A., Jess T., Kelly S.M., Cooper A., Price N.C., Pires E., Barros M. (2009) Acetonitrile-induced unfolding of porcine pepsin A. A proposal for a critical role of hydration structures in conformational stability. In: International Journal Of Biological Macromolecules. 45, 3, 213-220.
Sarmento A.C., Lopes H., Oliveira C.S., Vitorino R., Samyn B., Sergeant K., Debyser G., van Beeumen J., Domingues P., Amado F., Pires E., Domingues M.R.M., Barros M.T. (2009) Multiplicity of aspartic proteinases from Cynara cardunculus L. In: Planta. 230, 429-439.
Oliveira C.S., Sarmento A.C., Pereira A., Correia I., Pessoa J.C., Esteves V.I., Fonseca H., Pires E., Barros M. (2009) Non-native states of cardosin A induced by acetonitrile: activity modulation via polypeptide chains rearrangements. In: Journal Of Molecular Catalysis B: Enzymatic. 61, 274-278.
Oliveira C.S., Lázaro B., Azevedo J.N., Henriques I., Almeida A., Correia A. (2012) New Molecular Variants of Epsilon and Beta IncP-1 Plasmids are Present in Estuarine Waters. In: Plasmid. 67, 252-258.
Azevedo J.S.N., Ramos I., Araújo S., Oliveira C.S., Correia A., Henriques I. (2012) Spatial and temporal analysis of estuarine bacterioneuston and bacterioplankton using culture-dependent and culture-independent methodologies. In: Antonie Van Leeuwenhoek. 101, 819-835.
Moura A., Oliveira C., Henriques I., Smalla K., Correia A. (2012) Broad diversity of conjugative plasmids in integron-carrying bacteria from wastewater environments. In: Fems Microbiology Letters. 330, 2, 157-164.
Azevedo J.S.N., Araújo S., Oliveira C.S., Correia A., Henriques I. (2013) Analysis of antibiotic resistance in bacteria isolated from the surface microlayer and underlying water of an estuarine environment. In: Microbial Drug Resistance. 19, 64-71.
Oliveira C.S, Moura A., Henriques I., Brown C.J., Rogers L.M., Top E.M., Correia A. (2013) Comparative genomics of IncP-1 epsilon plasmids from water environments reveals diverse and unique accessory genetic elements. In: Plasmid. 70, 3, 412–419
Seabra M.P., Grave L., Oliveira C., Alves A., Correia A., Labrincha J.A. (2014) Porcelain stoneware tiles with antimicrobial action. In: Ceramics International. 40, 4, 6063-6070. 1873-3956.
Henriques I., Tacao M., Leite L., Fidalgo C., Araujo S., Oliveira C., Alves A. (2016) Co-selection of antibiotic and metal(loid) resistance in gram-negative epiphytic bacteria from contaminated salt marshes. In: Marine Pollution Bulletin. 109, 1, 427-434.
Capela M.N., Tobaldi D.M., Oliveira C., Pereira A., Duarte A.S., Seabra M.P., Fernandes M.H.V. (2017) Bioactivity and antibacterial activity against E. coli of calcium-phosphatebased glasses: Effect of silver content and crystallinity. In: Ceramics International. 43, 16, 13800-13809.
Other Papers (0)
Books (0)
Book Chapter (0)
Thesis (6)
Oliveira C.S. (2007) Estados conformacionais da cardosina A. In: PhD Thesis.
Oliveira C.S. (2001) Efeito dos solventes orgânicos na estrutura secundária da cardosina A. In: MSc Thesis.
Cortez M.T.S.C. (2009) Abordagem molecular na resolução de problemas com biocorrosão. In: MSc Thesis.
Pinto B.L. (2010) Plasmídeos com Gama Alargada de Hospedeiros em Ambientes Estuarinos. In: MSc Thesis.
Lara Torres Conde (2017) Diversidade de Plasmídeos no ambiente e desenvolvimento de ferramentas moleculares para a sua caracterização. In: MSc Thesis.
Lara Torres Conde (2017) Diversidade de Plasmídeos no ambiente e desenvolvimento de ferramentas moleculares para a sua caracterização. In: MSc Thesis.
Communications (30)
Sarmento A.C., Oliveira Cláudia S., Pereira A. O., Esteves Valdemar, Saraiva Jorge, Correia Isabel, Pessoa João Costa, Pires Euclides, Barros Marlene (2006) Using Cardosina A as a Model protein. In:
Oliveira C. (2001) Conformational Study of cardosine A in organic solvents by limited proteolysis and FTIR spectroscopy. In:
Sarmento A.C., Pereira A.O., Oliveira C.S., Pina D., Shnyrova A., Shnyrov V., Pires E., Barros M.T. (2004) A conformational and functional approach: effects of acetonitrile and chemical denaturants on an aspartic proteinase, cardosin A. In:
Sarmento A.C., Oliveira C.S., Pina D., Shnyrov V., Halling P.J., Pires E., Villar E., Barros M.T. (2001) Cardosin A as a model aspartic proteinase for studies of enzyme behaviour in the presence of organic solvents. In:
Sarmento A.C., Oliveira C.S., Pereira A., Pires E.M., Barros M.T. (2007) A case study: cardosin A as a model for aspartic proteinases conformational stability. In:
Silva P., Sarmento A.C., Oliveira C.S., Pires E., Barros M. (2006) Conformational effect of acetonitrile on an aspartic proteinase, Cardosin A. In:
Sarmento A.C., Oliveira C.S., Pereira A. O., Pires E., Barros M. (2006) Using organic solvents to characterise conformational intermediaries of protein unfolding. In:
CS Oliveira, , AC Sarmento, DG Pina, H Fonseca, E Pires, V Shnyrov, M Barros (2003) Stability of cardosin A from Cynara cardunculus L: a dimeric aspartic proteinase. In:
Sarmento A.C., Oliveira C.S., Pires E., Barros M. (2003) The potential of cardosin A as a proteolytic probe. In:
Sarmento A.C., Oliveira C.S., Cardoso T., Fonseca H., Pires E., Barros M. (2002) How proteins can be characterised using organic solvents. In:
Oliveira C.S., Sarmento A.C., Pires E., Barros M. (2000) Towards an Understanding of Cardosin A Behaviour in Biphasic Systems. In:
Sarmento A.C., Oliveira C.S., Pereira A. O., Cardoso T., Barros M. (2005) Old techniques with nowadays applications and promising perspectives. In:
Sarmento A.C., Oliveira C.S., Halling P., Pires E., Barros M. (2002) Studies of enzyme behaviour in non-conventional environments. In:
Oliveira C.S., Sarmento A.C., Pina D., Shnyrov V., Fonseca H., Pires E., Barros M. (2002) Limited proteolysis in mixed organic-aqueous solvent systems. A new tool for protein structure assessment. In:
Oliveira C.S., Sarmento A.C., Pina D., Shnyrov V., Pires E., Barros M. (2001) An overview of structural stability studies of proteins: cardosin A a plant aspartic proteinase with antifibrotic potential. In:
Sarmento A.C., Barros M., Pires E. (1998) The Application of two Aspartic Proteinases, Cardosins A and B on Peptide Synthesis. In:
Pina D., Oliveira C.S., Sarmento A.C., Barros M., Villar E., Shnyrov V. (2001) Structural stability of cardosin A an aspartic proteinase from Cynara cardunculus L. In:
Oliveira C.S., Sarmento A.C., Esteves V., Duarte A., Pina D., Shnyrov V., Pires E., Barros M. (2001) Conformational study of cardosin A in organic solvents by limited proteolysis and FTIR spectroscopy. In:
Pina D., Oliveira C.S., Sarmento A.C., Barros M., Villar E., Shnyrov V.L. (2002) Desnaturalización térmica y química de las cardosinas A, B y A0. In:
Cardoso T., Sarmento A.C., Oliveira C.S., Pires E., Barros M. (2004) Understanding the effects of acetonitrile on pepsin stability. In:
Sarmento A.C., Lopes H., Oliveira C.S., Vitorino R., Pires E., Domingues P., Domingues M.R., Barros M. (2005) Purification and characterisation of aspartic proteinases from C. cardunculus L. In:
Oliveira C., Nina J., Moura A., Henriques I., Correia A. (2008) Bacterioneuston versus bacterioplankton: culture independent approach to screen for broad host range plasmids, antibiotic resistance and integron gene sequences. In:
Azevedo J., Ramos I., Oliveira C., Henriques I., Correia A. (2009) Unraveling differences between bacterioplankton and bacterioneuston: universal or specific primers?. In:
Oliveira C.S, Bresciani V., Almeida A., Correia A. (2009) Conjugative gene transfer and BHR plasmids incidence from the SML and subsurface waters: an estuary from Portugal as a case study. In:
Oliveira C.S, Almeida A., Correia A. (2010) Does the surface microlayer environment select for specific microbial communities? Investigating the role of horizontal gene transfer. In:
Oliveira C.S, Lázaro B., Henriques, I., Almeida A., Correia, A. (2011) Epsilon and beta incP-1 plasmids are present in estuarine aquatic environments, a new source of BHR plasmids. In:
Oliveira C.S, Moura A., Henriques I., Rogers L., Brown C, Top E., Correia A (2012) Comparative genomics and resistance phenotypes of IncP-1epsilon plasmids from estuarine waters. In:
Martins S., Moura A., Oliveira C., Correia A. (2013) The gene pool of sequenced plasmids – what can we learn?. In:
Araújo S., Tacão M., Leite L., Oliveira C., Alves A., Henriques I. Effect of metal contamination on antibiotic resistance traits in epiphytic bacteria. . In:
Araújo S., Tacão M., Leite L., Oliveira C., Alves A., Henriques I. Effect of metal contamination on antibiotic resistance traits in epiphytic bacteria. In:
Other Publications (2)
Sarmento A.C., Lopes H., Oliveira C.S., Vitorino R., Pires E.M., Domingues P., Domingues M.R., Barros M.T. (2005) Purification and characterisation of aspartic proteinases from C. cardunculus L.. FEBS J. 272 Suppl 1. In:
Oliveira C.S., Sarmento A.C., Pina D., Shnyrov V., Pires E., Barros M. (2001) Structural stability characterisation of cardosin A from Cynara cardunculus L.: enzymic, spectroscopic and calorimetric studies. Arquivos de Patologia, vol. XXXIII supp. In:

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