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Fernanda Oliveira Esteves Rosário

Fernanda Oliveira Esteves Rosário

PhD Student

  • Department: Biology
  • Research Group: Stress Biology
  • Thesis title: Unrevealing pathways of cyto and genotoxicity of AgNP in lung and osteosarcoma cells: in vitro approach Supervisor: Maria Conceição Santos, Helena Oliveira and Peter Hoet Category: BO Grant type: BD Funding entity: FCT Grant reference: SFRH/BD/91270/2012 Start date: 2013-01-03 End date: 2017-01-03


Academic Career

09/2008 - 07/2009
Scholarship for Scientific Research at Universidade de Aveiro, funded by FCT 
Main activities and responsibilities:
Maintenance of cultures of Porcellionides pruinosus; measuring basal levels of biomarkers and energy reserves; Realization of soil and feeding tests; Parameters calculation (Electron Transpot System (ETS) and Cellular Energy Allocation (CEA)) and statistical analysis of the obtained data. 


09/2009 - 07/2010
Internship in Brazil (Rio de Janeiro), at Labtox, Laboratório de Análise Ambiental Ltda 
Main activities and responsibilities: Culture and maintenance of aquatic organisms: Mysidopsis juniae, Artemia sp, Ceriodaphnia dubia, Hyalella azteca and Danio rerio. Realization of acute and chronic ecotoxicity tests with metals in aquatic organisms (Mysidopsis juniae).


09/2010 - 12/2012
MSc degree in Molecular and Cellular Biology at Universidade de Aveiro, under Helena Oliveira and Maria Conceição Santos orientation. With the teme: Effects of Silver Nanoparticles on Osteosarcoma and Lung Cell Lines.

Additional training


  • 28/5/2012 – 2/6/2012 - University of Aveiro
    Advanced Workshop - “Implications of nanomaterials: A hands on course on synthesis, characterizations, and ecotoxicology, 4th edition”



  • 16/5/2012 - University of Aveiro
    Workshop - “Required calculations for biological work”



  •  9/5/2012 - University of Aveiro
    Biotechnology Workshop of University of Aveiro 



  • 19/09/2010 – 23/09/2010 - Bombinhas - Brazil
    XI Brazilian Congress of ecotoxicology - ECOTOX



  • 30/03/2007 – 02/04/2007 - University of Aveiro
    XI National Meeting of Biology Students "Biological Interactions"

Projects

ASSAY: Assessment of fate and effects of Silver nanoparticleS in Aquatic ecosYstems


http://assay.bio.ua.pt

Research Interests


Current interest area: Cito/genotoxicity in human cells. Cellular and molecular biology. Changes in the cell cycle, apoptosis/necrosis, mitochondrial bioenergetics, gene expression, detection of micronuclei and DNA damage, oxidative stress pathways. 

Nanoparticles and emerging stressors. 

General Research Interests: Environmental Toxicology, ecotoxicological evaluation of contaminated waters and soils. Studies of molecular biomarkers as ecotoxicological tool. Species used: Porcellionides pruinosus (isopod).




Scientific Supervision

In progress
Concluded

Projects

In progress
Concluded

Publications

WoS Papers (2)
Rosario F., Hoet P., Santos C., Oliveira H. (2016) Death and cell cycle progression are differently conditioned by the AgNP size in osteoblast-like cells. In: Toxicology. 368, 103-115.
Rosário F, Hoet P, Nogueira AJA, Santos C, and Oliveira H (In press) Differential pulmonary in vitro toxicity of two small sized polyvinylpyrrolidone coated silver nanoparticles. In: Journal Of Toxicology And Environmental Health, Part A.
Other Papers (2)
Remédios C, Rosário F, Bastos V (2012) Environmental Nanoparticles Interactions with Plants: Morphological, Physiological, and Genotoxic Aspects. In: Journal Of Botany. doi:10.1155/2012/751686,
Rosário F, Reis C, Santos C, Oliveira H, Ferreira de Oliveira JMP (2014) Cyto and genotoxic effects of silver nanoparticles on A549 cell line. In: Toxicol Lett. 229,
Books (0)
Book Chapter (0)
Thesis (0)
Communications (11)
Ferreira, N.G.C., Rosário, F., Domingues, I., Calhôa, C. F. , Soares, A. M. V. M., Loureiro, S. (2009) Basal levels of biomarkers and energetic reserves in Porcellionides pruinosus. In:
Ferreira, N.G.C., Rosário, F., Domingues, I., Calhôa, C. F., Soares, A. M. V. M. , Loureiro, S. (2009) Biomarkers and energetic reserves in isopods: tools to assess stress exposure. In:
Ferreira, N.G.C., Rosario, F., Domingues, I., Calhôa. F, Soares, A.M.V.M., Loureiro, S. (2009) Biomarkers and energetic reserves in isopods: tools to assess stress exposure. In:
Ferreira, N.G.C., Rosario, F., Domingues, I., Calhôa. C. F., Soares, A.M.V.M., Loureiro, S. (2009) Basal levels of biomarkers and energetic reserves in Porcellionides pruinosus. In:
Rosário F, , Oliveira H, Oliveira M, Santos C (2012) Evaluation of AgNP nanoparticles on osteosarcoma viability: approaches to environmental studies. In:
Rosário F., Oliveira H., Oliveira M., Santos C. (2012) In Vitro assessment of the effects of silver nanoparticles on osteosarcoma viability: Uncoated vs Coated nanoparticles. In:
Bastos V., Rosário F., Oliveira H., Oliveira M., Santos C. (2012) Toxicity assessment of uncoated Ag and TiO2 nanoparticles on human osteosarcoma cell lines. In:
Rosário F., Bastos V., Oliveira H., Oliveira M., Santos C. (2012) Nanoparticles Interactions with Plants. In:
Oliveira H., Rosário F., Bastos V., Oliveira M., Santos C. (2012) Avaliação in vitro da toxicidade de nanopartículas de prata (AgNPs) em células humanas. In:
Rosário F., Oliveira H., Nogueira A., Santos C. (2013) Effects of silver nanoparticles on lung cells: In vitro approach. In:
Reis C., Rosário F., Oliveira H., Nogueira A., Santos C. (2013) Genotoxic effects of silver nanoparticles on A549 cell line. In:
Other Publications (1)
Ferreira, N. G. C., Rosário, F. , Domingues, I., Calhôa, C. F. , Soares, A. M. V. M. , Loureiro, S. (2010) Acetylcholinesterase Characterization in the Terrestrial Isopod Porcellionides pruinosus in Biological Responses to Chemical Contaminants: From Molecular to Community Level Vol.3: 227-236. In:

CESAM Funding: