HOME  »  Members  »  Collaborators  »  PhD Students/Fellows
 
  Joana Barbosa  
  Phone: +351 912619999  
  e-mail: jcbarbosa@ua.pt  
  Category: PhD student  
  Department: Department of Biology  
  Research group: Stress Biology
 
 
  Direct URL for this page: http://www.cesam.ua.pt/jcbarbosa  
     
  Thesis title: Improvement and elucidation of lantibiotic production in Escherichia coli
  Supervisor: Sónia Mendo
  Category: BO
  Grant type: BD
  Funding entity: Fundação para a Ciência e Tecnologia (FCT)
  Grant reference: SFRH/BD/97099/2013
  Start date: 2014-12-01
  End date: 2018-11-30
ORCID


orcid.org/0000-0001-9437-5687

Awards

IV Symposium on Bioengineering, 2012, Lichenicidin Bioengineering: peptides with changed bioactivity., Barbosa J, Cruzeiro J, Süssmuth R, Caetano T, Mendo S. Faculdade de Engenharia da Universidade do Porto (FEUP), Portugal – Poster contest 2nd prize

Academic Career

09/2010 – 07/2012: Master in Molecular Biotechnology at University of Aveiro (Aveiro, Portugal). Final classification: 17 values (out of 20 values)


02/2011 – 07/2011: Participant of Erasmus program at University of Pavia (Pavia, Italy).


09/2007 – 07/2010: Degree in Biotechnology at University of Aveiro (Aveiro, Portugal). Final classification: 15 values (out of 20 values)


 

Projects
Coli4Lan - Better systems to produce two ­peptide lantibiotics with diverse structures completely in vivo using Escherichia coli and establishment of their mode of action. [see details]

Publications
  1. Barbosa J., Caetano T., Mendo S. (2015) Class I and Class II Lanthipeptides Produced by Bacillus spp. Journal Of Natural Products. 78, 11, 2850-2866. (see details) ISI paper
    Link: http://pubsdc3.acs.org/doi/full/10.1021/np500424y
  2. Caetano T., Barbosa J., Moesker E., Sussmuth R.D., Mendo S. (2014) Bioengineering of lanthipeptides in Escherichia coli: assessing the specificity of lichenicidin and haloduracin biosynthetic machinery. Research In Microbiology. 165, 7, 600-604. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S0923250814001089
  1. Barbosa J. (2012) Lichenicidin: Regulation, Expression and bioengineering in E. coli. MSc Thesis. (see details)
    Link: http://ria.ua.pt/handle/10773/9548
  1. Barbosa J., Caetano T., Mendo S. (2015) Lichenicidin directed mutagenesis: how changes in charged amino acids affect bioactivity. (see details)
  2. Barbosa J. (2014) Heterologous expression of lichenicidin: improvement of the biosynthesis levels in E. coli. (see details)
  3. Caetano T., Barbosa J., Cruzeiro J., Suessmuth, R.D., Mendo, S. (2013) Random mutagenesis of the lantibiotic linchenicidin in E. coli. (see details)
  4. Barbosa J., Caetano T., Suessmuth R.D., Mendo S. (2013) Directed evolution of the lantibiotic lichenicidin. (see details)
  5. Barbosa J., Caetano T., Suessmuth R.D., Mendo S. (2013) Heterologous expression of lichenicidin: improvement of the biosynthesis levels in E. coli. (see details)
  6. Caetano T., Suessmuth R.D., Mendo S. (2013) Insights into the lichenicidin self-protection mechanism using E. coli as model organism. (see details)
  7. Barbosa J., Caetano T., Süssmuth R., Mendo S. (2013) Lichenicidin production: construction of expression systems. (see details)
  8. Barbosa J., Caetano T., Mendo S. (2013) Directed Evolution of the lantibiotic lichenicidin. (see details)
  9. Barbosa J., Cruzeiro J., Süssmuth R., Caetano T., Mendo S. (2012) Lichenicidin Bioengineering: peptides with changed bioactivity. (see details)
  10. Caetano T., Barbosa J., Cruzeiro J., Jorge R., Süssmuth R., Mendo S. (2012) Search for new lantibiotics: case study of lichenicidin. (see details)
  11. Barbosa J., Caetano T., Süssmuth R., Mendo S. (2012) Lichenicidin: heterologous expression and biosynthesis comparison. (see details)