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  Sónia Mendo  
  Phone: +351 234 247015  
  e-mail: smendo@ua.pt  
  Category: Assistant Professor with Habilitation  
  Department: Biology  
  Research group: Stress Biology
 
ISI Web of KnowledgeSM search factor: Author=(Mendo S) AND Address=(Aveiro)  
  Direct URL for this page: http://www.cesam.ua.pt/smendo  
     

Born in Lobito, Angola, 16th December 1962. Married, two children. BSc in Microbiology (1989) University of Kent at Canterbury, UK. Ph.D. (1998) in Biology -Microbial Biotechnology, University of Lisbon. Habilitation (2013), University of Aveiro. Since 2000, Assistant Professor at Biology Department of the University of Aveiro. 

MAIN RESEARCH ACTIVITY AND INTERESTS

Scopus Author ID: 6505928827:https://www.scopus.com/authid/detail.uri?authorId=6505928827


Google Scholar: https://scholar.google.pt/citations?user=SgLu4HQAAAAJ&hl=pt-BR


Researcher ID: http://www.researcherid.com/ri.....



  • Search for new antimicrobials: Lantibiotics and traditional antibiotics;

  • Resistance mechanisms to xenobiotics in bacteria;

  • Genotoxicity studies in vertebrates and invertebrates exposed to environmental contaminants.

Habilitation in Biology

  • BSc Honours in Microbiology (1989), University of Kent, Caterbury, UK; 

  • PhD in Biology – Microbial Biotechnology (1998), Faculty of Sciences, University of Lisbon;

  • Habilitation in BIology (January 2013)

ACTIVITIES/POSITIONS

  • Assistant Professor with Habilitation, Department of Biology, University of Aveiro (since 2013)

  • Assistant Professor, Department of Biology, University of Aveiro (since 1999)

  • Chaiman of the board of equivalences of the Department of Biology, University of Aveiro (since 2004)

  • Coordinator of the MSc Degree in Molecular Microbiology, Department of Biology, University of Aveiro (3rd to 5th editions)

  • Committee Member of the  of the MSc in Microbiology, Department of Biology, University of Aveiro (since 2007)

  • Director of the MSc in MIcrobiology, Department of Biology, University of Aveiro (since September 2011)

  • National coordinator of COST (CM0804), Chemical Biology with Natural Products

RESEARCH PROJECTS

PARTICIPATE/ED AS TEAM MEMBER IN THE FOLLOWING RESEARCH PROJECTS:



  • Projecto Icentro: Redução do teor de sulforoso de vinhos. Funded by IC-01-01_FDR-0153 (Mar 2008-Jun 2009)

  • Projecto QREN : "WineSulFree" - Avaliação de tecnologias que permitam a redução do teor de sulfitos dos vinhos -Financiado pelo QREN - SI I&DT Co-Promoção (projecto nº3462), Agosto de 2009-2011).

  • WineSulFree - Establishment of the scientific basis for the development of new technologies to substitute sulphur dioxide in wine. Projectos I&D PTDC/AGR-ALI/101251/2008

  • Projecto Sal do Atlântico: "Revalorização da identidade das salinas do atlântico. Recuperação e promoção do potencial biológico, económico e cultural das zonas húmidas costeiras" (Programa comunitário de apoio Interreg III B Espaço Atlântico) (2004-2007)

  • Diferenciação Genética e morfológica em organismos estuarinos com padrões de dispersão contrastantes ao longo de um gradiente geográfico. Projecto POCTI/BSE/45672/2002 (2003-2006); Projecto de I&D da Universidade de Aveiro, Abordagem molecular para despistagem de bactérias patogénicas, OE 3.64.33.8 (2003-2005)

  • Conservação e valorização dos recursos genéticos de pomóideas regionais. Projecto do Programa AGRO; Medida 8-Desenvolvimento Tecnológico e Demonstração; Acção 8.1- Desenvolvimento Experimental e Demonstração - DE&D (2001-2004)

  • Projecto REI- Ensaios de reflorestação da Ilha de Porto Santo usando plantas autócnes regeneradas in vitro e adaptadas a stress hídrico, PNAT/1999/AGR/15011 (2000-2004); Estudo da função de uma alteração ao código genético na evolução de novos fenótipos em Candida albicans, Projecto Praxis/P/BIA/1139/1998 (1999- 2001).


PRINCIPAL INVESTIGATOR OF THE FOLLOWING RESEARCH PROJECTS:



  • Isolation and caracterisation of the genes involved in tributyltin (TBT) in marine bacteria. POCI/MAR/56475/2004, started in October, 2005; Total Budget: 54K€.

  • TBTRESENSE - Bioremediation of TBT development of a biosensor system to detect TBT form contaminates sites (PTDC/MAR/108024/2008); started in April, 2005; Total Budget: 176K€

  • ENGENUR: Definition of new endpoints to assess and discriminate genotoxic effects resulting from environmental exposures to uranium, uranium daughter radionuclides and ionizing radiation in bioindicator species. Projecto PTDC/AAC-AMB/114057/2009. 172.944 €; Janeiro 2011-Janeiro 2013.Total Budget: 173K€

POST GRADUATION SUPERVISION

  • Scientific Supervisor of more than 30 MSc students and 6 PhD (all concluded)

  • Presently supervising, 2 Post Dc, 3 PhD and 5 MSc students.

FCT PUBLIC KEY

  • J0013655185

ISOLATION AND CHARACTERIZATION OF THE GENES INVOLVED IN TRIBUTYLTIN- TBT- RESISTANCE IN MARINE BACTERIA POCI/MAR/56475/2004 (POCI2010/FEDER)

  • ABSTRACT: The main objective of this project is to study and understand the behaviour and the mechanisms behind TBT resistance by marine estuarine bacteria. The approach will include the isolation of culturable marine bacterial isolates that will allow for the detection and isolation of the genes involved in TBT resistance. Additionally bacterial communities will also be studied as they constitute the base of aquatic food webs and are responsible for the bulk of organic matter transformations and mineral recycling in aquatic environments. Also, due to the various sensitivities of different microorganisms to toxic chemicals and the dominance of highly diverse microbes in natural environments and, bacterial community responses to the toxic effect of TBT will also be analyzed. Specific objectives are related and constitute specific work tasks: i) Isolation, identification and characterization of TBT resistant/tolerant culturable bacteria A from where a collection of TBT resistant/tolerant bacteria will be selected for further studies ii) Microbial community-level toxicity testing where community-level toxicity testing of chemicals should supplement single-species laboratory assays when testing potential harmful chemicals like TBTs, iii) Characterization of bacterial abundance, viability, activity and functional diversity designed to compare bacterial density, viability, activity and functional diversity of bacterial communities in coastal waters in order to evaluate the effect of TBT on bacterial metabolism, iv) TBT degradation assay to demonstrate the mechanism behind TBT resistance/tolerance by marine bacteria and v) Isolation and characterization of the genes involved in TBT resistance. It is well known that isolation and culturing techniques miss out a large part of the bacterial community. Therefore the use of molecular techniques will enable us to select interesting organisms for a future construction of microbial consortia with TBT degrading capabilities. The proposed study will allow for the isolation of the encoded TBT resistance genes in marine bacteria that is of extreme importance for future research.

PROJECT: POCI/MAR/56475/2004 (POCI2010/FEDER)

  • MAIN RESULTS: Isolation, identification and characterization of TBT resistant/tolerant culturable bacteria A significant difference was observed between isolates belonging to the same genera. No significant correlation between strains isolated from a more polluted area (water) and strains collected at the less polluted area (sediment). Medium-organometal interactions may affect metal toxicities. Despite the heterogeneity Gram negative and are generally more resistant to TBT. Memory response to TBT exposure We proposed the existence of a ‘memory response’ mechanism to TBT/toxicant exposure. Nonetheless, the relation between the ‘memory response’ to TBT concentration and the resistant bacteria on a given natural environment could not be made as other factors (presence of other toxic compounds) could influence the ‘memory’ mechanism response. A. molluscorum Av27 was selected for a series of studies due to its high TBT resistance and also to the ability to degrade it to lesser toxic compounds (DBT and MBT). TBT microbial community-level toxicity and degradation DGGE (37-65%) analysis of microcosm communities showed that the time interval applied to autoclaved samples was not enough to eliminate all the bacteria present. Possibly, sporulating/slow growing anaerobic bacteria were not destroyed and were able to grow after some time of incubation. Also the organic matter present in the microcosm could protect some of bacteria, as growth was detected after 30 days of incubation. The TBT concentration used seems to be lethal to some bacteria after 5 days, as a decrease of the bacterial community was observed (samples 7, 8 and 22, 23). However, after 30 days, the community recovered, maybe due to the lower concentration of TBT due to its degradation by bacteria that were still present. The addition of Av27 did not seem to have an impact, maybe because A. molluscorum is already part of the original (microcosm) community, and possibly is not a dominant bacteria in that environment. Characterization of bacterial abundance, viability, activity and functional diversity Bacterial viability analysis showed that TBT has influence on cells as they were smaller and appeared aggregated. This could be explained as an energy saving mechanism exhibited by the bacteria when exposed to TBT for long periods. Despite their resistance to TBT, bacteria cells are growing under stress conditions, due to the scarcity of nutrients. Other experimental results suggested that in TSB (rich) medium the cells can have a better performance, meaning that maybe the components of the medium can protect the cell to TBT exposition, by chelating TBT from the environment were cells are growing. TBT degradation Degradation of TBT in DBT occurred under laboratory conditions by A. molluscorum Av27, after 24 h in MB medium. Also, it seems that it is gradually exported, as DBT, after degradation inside the cell. This possibility was not proved yet due to some technical problems. Despite the debutylation of TBT results in less lipophilic compounds, due to cell activity, it appears that these compounds are still bound to the cell membrane lipids. The TBT degradation was compared when Av27 was growing in TSB (rich medium) and in MB. Results, demonstrated a higher degradation in MB medium suggesting that the rich medium does not promote an increase on TBT degradation. However, metabolic activity determinations suggested that TSB protects the cells from the TBT toxicity. Isolation and characterization of the genes involved in TBT resistance TBT resistance seems to be related with a gene that has high homology with sugE gene. RT-PCR and real time PCR analysis showed an increased expression of this gene, as revealed by an increase of the mRNA level when cells are grown in increasing TBT concentrations. This gene is part of the “small multidrug resistance family” (SMR) that has been described as being involved in the efflux of lipophilic drugs. It seems apparent that SugE-like protein plays a role in the transport of TBT, DBT or MBT outside or inside the bacterial cell, this mechanism is not elucidated yet. Total proteins analysis from cells of clone 69 growing in the presence of TBT, revealed that a protein of ~ 11 kDa is overexpressed. This protein could be related to the sugE (encoded on ORF P6). Other proteins are also overexpressed, 2 of those were identified as outer membrane proteins that could be related with the influx and efflux of TBT and also with its degradation products( DBT and MBT) from or into the cell. Another protein, ~ 57 kDa, was identified: groEL protein. This protein is a chaperonin with a major role on the renaturation of proteins, restoring its functional activity at the expense of ATP seems to be overexpressed due to TBT. TBT resistance: is the same resistance mechanism shared by other Aeromonas spp.? The same gene was found in bacteria of the same species. However different mechanism(s) might be responsible for TBT resistance in other Aeromonas spp.

1st INTERNATIONAL SYMPOSIUM BIOLOGICAL RESPONSES TO CHEMICAL CONTAMINANTS: FROM MOLECULAR TO COMMUNITY LEVEL

Interdisciplinary Symposium BIOLOGICAL RESPONSES TO CHEMICAL CONTAMINANTS: from molecular to community level, September 2-4, 2009 Aveiro University, Portugal



  • TOPICS: 1. BACTERIAL RESPONSES  Pollutant degradation  Resistance to chemicals 2. EUKARYOTIC RESPONSES  Response to contaminants in animals INVITED SPEAKERS JI-DONG GU, University of Hong Kong, Hong Kong CHIEH-CHEN HUANG, National Chung Hsing University, Taiwan KORNELIA SMALLA, Federal Biological Research Center for Agriculture and Forestry (BBA), Germany MARKO VIRTA, University of Helsinki, Finland HISATO IWATA, Ehime University, Japan NEWTON GOMES, Aveiro University, Portugal RUTH PEREIRA, Aveiro University, Portugal ISABEL HENRIQUES, Aveiro University, Portugal CORINA CIOCAN, University of Sussex, UK J.M.RUIZ, University of la Coruna, Spain


 


 



  • 77 national and international researchers from Spain,UK, Finland, France, Germany and Japan, participarted at the event.

OTHER ACTIVITIES ( Organization of scientific events)

XIII Congresso Ibérico de Citometria de Fluxo (SIC), 9 - 11 may 2013


Member of the organizing committee of Congresso Nacional de Microbiologia e Biotecnologia, 6 - 8 december 2013.

Researcher ID

E-1095-2011

Scientific Supervision
Post-doc (Main Supervisor): Joana Isabel do Vale Lourenço
Post-doc (Main Supervisor): Tânia Caetano
Post-doc (Co-supervisor): Anabela Cachada

PhD (Main Supervisor): Joana Barbosa

Master (Co-supervisor): Beatriz Almeida
(not a CESAM member)
Master (Co-supervisor): Ana Sofia Vaz
(not a CESAM member)
Master (Co-supervisor): Hugo Costa
(not a CESAM member)
Master (Co-supervisor): Ana Teresa Viana
(not a CESAM member)
Master (Co-supervisor): Bárbara Branco
(not a CESAM member)

Post-doc (Main Supervisor): Andreia Cruz
(ex-CESAM member)

PhD (Main Supervisor): Sonia Pascoal
(ex-CESAM member)
PhD (Main Supervisor): Tânia Caetano
PhD (Main Supervisor): Cátia Raquel Talhas Santos
PhD (Main Supervisor): Andreia Cruz
(ex-CESAM member)
PhD (Main Supervisor): Joana Isabel do Vale Lourenço
PhD (Main Supervisor): Sónia Ferreira
(ex-CESAM member)
PhD (Main Supervisor): Cátia Raquel Talhas Santos



Projects
NANOpartículas poliméricas BIogénicas funcionalizadas para adsorção de metais em aplicações amigas do ambiente: bioREmediação e bioSensores [see details]

Coli4Lan - Better systems to produce two ­peptide lantibiotics with diverse structures completely in vivo using Escherichia coli and establishment of their mode of action. [see details]

REpulse- Responses of Daphnia magna exposed to chemical pulses and mixtures throughout generations [see details]

ECOAPPROACH - Bridging the gap between metal contamination and ecologically significant effects on macrobenthic communities: a multidisciplinary approach from gene to community [see details]

ENGENUR - Definition of new ENdpoints to assess and discriminate GENotoxic effects resulting from environmental exposures [see details]

TBTRESENSE: Tributiyltin (TBT) bioremediation and development of a biosensor to detect TBT from contaminated sites. [see details]

Remediation Processes in uranium and other mining areas [see details]

CAPTAR-Science and Environment for All [see details]

Isolation and Characterization of the genes involved in TBT resistance in marine bacteria [see details]

Ecological risk assessment on the use of boat antifouling paints with organometallic and metallic biocides at the Portuguese coast (ECOBOAT) [see details]

“Salt of the Atlantic”: Revalorization of identity of the Atlantic Saltpans. Recuperation and promotion of biological, economic and cultural potential of coastal wetlands [see details]

Publications
  1. Cardoso D., Silva Ana R., Cruz A., Lourenço J., Neves J., Malheiro C., Mendo S., Soares A.M.V.M., Loureiro S. (in press) The comet assay in Folsomia candida : A suitable approach to assess genotoxicity in collembolans. (see details) ISI paper
    Link: http://dx.doi.org/10.1002/etc.3795
  2. Rodrigues R., Lourenço J., Pereira P., Carvalho S., Mendo S. (accepted for publication) Effects of metal contamination on the gene expression profile of two benthic species (Cerastoderma edule and Venerupis philippinarum) . (see details) ISI paper
  3. Silva A.R.R., Cardoso D.N., Cruz A., Pestana J.L.T., Mendo S., Soares A.M.V.M., Loureiro S. (2017) Multigenerational effects of carbendazim in Daphnia magna. Environmental Toxicology And Chemistry. 36, 2, 383-394. (see details) ISI paper
    Link: http://dx.doi.org/10.1002/etc.3541
  4. Santos C., Ramalheira E., Da Silva G., Mendo S. (2017) Genetically unrelated multidrug- and carbapenem-resistant Citrobacter freundii detected in outpatients admitted to a Portuguese hospital. Journal Of Global Antimicrobial Resistance. 8, 18-22. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S2213716516301199
  5. Covas C., Caetano T., Cruz A., Santos T., Dias L., Klein G., Abdulmawjood A., Rodriguez-Alcala L.M., Pimentel L.L., Gomes A., Freitas A.C., Garcia-Serrano A., Fontecha J., Mendo S. (2017) Pedobacter lusitanus sp nov., isolated from sludge of a deactivated uranium mine. International Journal Of Systematic And Evolutionary Microbiology. 67, 5, 1339-1348. (see details) ISI paper
  6. Correia B., Lourenco J., Marques S., Nogueira V., Gavina A., Rasteiro M.D., Antunes F., Mendo S., Pereira R. (2017) Oxidative stress and genotoxicity of an organic and an inorganic nanomaterial to Eisenia andrei: SDS/DDAB nano -vesicles and titanium silicon oxide. Ecotoxicology And Environmental Safety. 140, 198-205. (see details) ISI paper
  7. Lourenço J., Marques S., Carvalho F. P., Oliveira J., Malta M., Santos M., Gonçalves F., Pereira R., Mendo S. (2017) Uranium mining wastes: The use of the Fish Embryo Toxicity (FET) test to evaluate toxicity and risk of environmental discharge. 605–606, 391-404. (see details) ISI paper
  8. Ofoegbu P.U., Simao F.C.P., Cruz A., Mendo S., Soares A.M.V.M., Pestana J.L.T. (2016) Toxicity of tributyltin (TBT) to the freshwater planarian Schmidtea mediterranea. Chemosphere. 148, 61-67. (see details) ISI paper
  9. Pavlaki M.D., Araujo M.J., Cardoso D.N., Silva A.R.R., Cruz A., Mendo S., Soares A.M.V.M., Calado R., Loureiro S. (2016) Ecotoxicity and genotoxicity of cadmium in different marine trophic levels. Environmental Pollution. 215, 203-212. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.envpol.2016.05.010
  10. Lourenco J., Mendo S., Pereira R. (2016) Radioactively contaminated areas: Bioindicator species and biomarkers of effect in an early warning scheme for a preliminary risk assessment. Journal Of Hazardous Materials. 317, 503-542. (see details) ISI paper
  11. Joaquin de Lapuente, Joana Lourenço, Sonia A. Mendo, Miquel Borràs, Marta G. Martins, Pedro M. Costa and Mario Pacheco (2015) The Comet Assay and its applications in the field of ecotoxicology: a mature tool that continues to expand its perspectives. Frontiers In Genetics. 6, 180, (see details) ISI paper
  12. Caetano T., Sussmuth R.D., Mendo S. (2015) Impact of Domestication in the Production of the Class II Lanthipeptide Lichenicidin by Bacillus licheniformis I89. Current Microbiology. 70, 3, 364-368. (see details) ISI paper
    Link: http://dx.doi.org/10.1007/s00284-014-0727-0
  13. Santos T., Cruz A., Caetano T., Covas C., Mendo S. (2015) Draft genome sequence of Pedobacter sp. strain NL19, a producer of potent antibacterial compounds. . Genome Annoucements. 3, 2, e00184-15 (see details) ISI paper
    Link: http://genomea.asm.org/content/3/2/e00184-15.full
  14. Silva A.R.R., Cardoso D.N., Cruz A., Lourenco J., Mendo S., Soares A.M.V.M., Loureiro S. (2015) Ecotoxicity and genotoxicity of a binary combination of triclosan and carbendazim to Daphnia magna. Ecotoxicology And Environmental Safety. 115, 279-290. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.ecoenv.2015.02.022
  15. Dias D., Torres R.T., Kronvall G., Fonseca C., Mendo S., Caetano T. (2015) Assessment of antibiotic resistance of Escherichia coli isolates and screening of Salmonella spp. in wild ungulates from Portugal. Research In Microbiology. 166, 7, 584-593. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S0923250815000583
  16. Cruz A., Rodrigues R., Pinheiro M., Mendo S. (2015) Transcriptomes analysis of Aeromonas molluscorum Av27 cells exposed to tributyltin (TBT): Unravelling the effects from the molecular level to the organism. Marine Environmental Research. 109, 132-139. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.marenvres.2015.06.017
  17. Barbosa J., Caetano T., Mendo S. (2015) Class I and Class II Lanthipeptides Produced by Bacillus spp. Journal Of Natural Products. 78, 11, 2850-2866. (see details) ISI paper
    Link: http://pubsdc3.acs.org/doi/full/10.1021/np500424y
  18. Dias L., Caetano T., Pinheiro M., Mendo S. (2015) The lanthipeptides of Bacillus methylotrophicus and their association with genomic islands. Systematic And Applied Microbiology. 38, 8, 525-533. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S072320201500154X
  19. Cruz A., Anselmo A.M., Suzuki S., Mendo S. (2015) Tributyltin (TBT): A Review on Microbial Resistance and Degradation. Critical Reviews In Environmental Science And Technology. 45, 9, 970-1006. (see details) ISI paper
    Link: http://dx.doi.org/10.1080/10643389.2014.924181
  20. Silva P.V., Silva A.R.R, Mendo S., Loureiro S. (2014) Toxicity of tributyltin (TBT) to terrestrial organisms and its species sensitivity distribution. Science Of The Total Environment. 466–467, 1037–1046 (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.scitotenv.2013.08.002
  21. Cruz A., Moreira R., Mendo S. (2014) An easy, rapid and inexpensive method to monitor tributyltin (TBT) toxicity in the laboratory. Folia Microbiologica. 59, 3, 203-207. (see details) ISI paper
    Link: http://dx.doi.org/10.1007/s12223-013-0284-0
  22. Cruz A., Henriques I., Sousa A.C.A., Baptista I., Almeida A., Takahashi S., Tanabe S., Correia A., Suzuki S., Anselmo A.M., Mendo S. (2014) A microcosm approach to evaluate the degradation of tributyltin (TBT) by Aeromonas molluscorum Av27 in estuarine sediments. Environmental Research. 132, 430-437. (see details) ISI paper
  23. Caetano T., Barbosa J., Moesker E., Sussmuth R.D., Mendo S. (2014) Bioengineering of lanthipeptides in Escherichia coli: assessing the specificity of lichenicidin and haloduracin biosynthetic machinery. Research In Microbiology. 165, 7, 600-604. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S0923250814001089
  24. Gama S., Rodrigues I., Marques F., Palma E., Correia I., Carvalho M.F.N.N., Pessoa J.C., Cruz A., Mendo S., Santos I.C., Mendes F., Santos I., Paulo A. (2014) New ternary bipyridine-terpyridine copper(II) complexes as self-activating chemical nucleases. Rsc Advances. 4, 106, 61363-61377. (see details) ISI paper
  25. Lourenço J., Pereira R., Gonçalves F., Mendo S. (2013) SSH gene expression profile of Eisenia andrei exposed in situ to a naturally contaminated soil from an abandoned uranium mine. Ecotoxicology And Environmental Safety. 88, 16–25 (see details) ISI paper
  26. Cruz A., Micaelo N., Félix V., Song J., Kitamura S., Suzuki S., Mendo S. (2013) sugE: a gene involved in tributyltin (TBT) resistance of Aeromonas molluscorum Av27. Journal Of General And Applied Microbiology. 59, 1, 39-47. (see details) ISI paper
  27. Lourenço J., Pereira R., Gonçalves F., Mendo S. (2013) Metal bioaccumulation, genotoxicity and gene expression in the European wood mouse (Apodemus sylvaticus) inhabiting an abandoned uranium mining area. Science Of The Total Environment. 443, 673–680 (see details) ISI paper
  28. Pascoal S., Carvalho G., Vasieva O., Highes R., Cossins A., Fang Y., Ashelford K., Olohan L., Barroso C., Mendo S., Creer S. (2013) Transcriptomics and in vivo tests reveal novel mechanisms underlying endocrine disruption in an ecological sentinel, Nucella lapillus. Molecular Ecology. 22, 6, 1589-1608. (see details) ISI paper
  29. Lourenço J., Pereira R., Pinto F., Caetano T., Silva A., Carvalheiro T., Guimarães A., Gonçalves F., Paiva A., Mendo S. (2013) Biomonitoring a human population inhabiting nearby a deactivated uranium mine. Toxicology. 305, 8, 89-98. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S0300483X13000164
  30. Pinheiro J.N, Marques C.R., Pinto G., Mestiri A., Gomes N.C.M., Mendo S., Gonçalves F., Rocha-Santos T., Duarte A.C., Römbke J., Sousa J.P., Ksibi M., Haddioui A., Pereira R. (2013) The performance of Fraxinus angustifolia as a helper for metal phytoremediation programs and its relation to the endophytic bacterial communities. Geoderma. 202, 171-182. (see details) ISI paper
  31. Cruz A., Areias D., Duarte A., Correia A., Suzuki A., Mendo S. (2013) Aeromonas molluscorum Av27 is a potential tributyltin (TBT) bioremediator: phenotypic and genotypic characterization indicates its safe application. Antonie Van Leeuwenhoek. 104, 385-396. (see details) ISI paper
  32. Cruz A., Oliveira V., Baptista I., Almeida A., Cunha A., Suzuki S., Mendo S. (2012) Effect of tributyltin (TBT) in the metabolic activity of TBT-resistant and sensitive estuarine bacteria. Environmental Toxicology. 27, 1, 11-17. (see details) ISI paper
    Link: http://www.ncbi.nlm.nih.gov/pubmed/20549634
  33. Lourenço J., Pereira R., Silva A., Carvalho F., Oliveira J., Malta M., Paiva A., Gonçalves F., Mendo S. (2012) Evaluation of the sensitivity of genotoxicity and cytotoxicity endpoints in earthworms exposed in situ to uranium mining wastes. Ecotoxicology And Environmental Safety. 75, 46-54. (see details) ISI paper
  34. Oldach F., Al-Toma R., Kuthning A., Caetano T., Mendo S., Budisa N., Suessmuth R.D. (2012) Congeneric Lantibiotics from In Vivo Ribosomal Peptide Synthesis with non-canonical Amino Acids. Angewandte Chemie - International Edition. 51, 2, 415-418. (see details) ISI paper
    Link: http://onlinelibrary.wiley.com/doi/10.1002/anie.201106154/abstract
  35. Pascoal S. C., Carvalho G., Creer S., Rock J., Kawaii K., Mendo S., Hughes R. (2012) Plastic and Heritable Components of Phenotypic Variation in Nucella lapillus: An Assessment Using Reciprocal Transplant and Common Garden Experiments. Plos One. 7, 1, e30289 (see details) ISI paper
  36. Cruz, A., Rodrigues, R., Barroso, C, Mendo, S. (2012) Aeromonas molluscorum Av27 transcriptome analysis: future applications for TBT detection and remediation. Febs Journal . 279 , supl. 1, 231-232. (see details) ISI paper
  37. Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2011) A novel complex class 1 integron found in a Klebsiella pneumoniae isolate from Portugal. Clinical Microbiology And Infection. 17, 7, 1036-1039. (see details) ISI paper
    Link: http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2010.03416.x/abst...
  38. Lourenço J., Pereira R., Silva A., Morgado J., Carvalho F., Oliveira J., Malta M., Paiva A., Mendo S., Gonçalves F. (2011) Genotoxic endpoints in the Earthworms Sub-Lethal Assay to Evaluate Natural Soils Contaminated by Metals and Radionuclides. Journal Of Hazardous Materials. 186, 1, 788-795. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.jhazmat.2010.11.073
  39. Caetano T., Krawczyk J.M., Moesker E., Suessmuth R.D., Mendo S. (2011) Heterologous Expression, Biosynthesis, and Mutagenesis of Type II Lantibiotics from Bacillus licheniformis in Escherichia coli. Chemistry & Biology. 18, 1, 90-100. (see details) ISI paper
    Link: http://www.cell.com/chemistry-biology/abstract/S1074-5521%2810%2900445-X
  40. Gonçalves O., Pereira R., Coimbra M.A., Gonçalves F., Mendo S., Rocha S. (2011) Evaluation of the mutagenicity of sesquiterpenic compounds and their influence on the susceptibility towards antibiotics of two clinically relevant bacterial strains. Mutation Research-genetic Toxicology And Environmental Mutagenesis. 723, 1, 18-25. (see details) ISI paper
  41. Caetano T., Krawczyk J.M., Moesker E., Suessmuth R.D., Mendo S. (2011) Two component lantibiotics biosynthesis in E. coli: licFGEHI immunity genes are not essential for lichenicidin production and self-protection. Applied And Environmental Microbiology. 77, 14, 5023-5026. (see details) ISI paper
    Link: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3147384/
  42. Lourenço J., Silva A., Carvalho F., Oliveira J., Malta M., Mendo S., Gonçalves F., Pereira R. (2011) Histopathological changes in the earthworm Eisenia andrei associated with the exposure to metals and radionuclides. Chemosphere. 85, 1630-1634. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.chemosphere.2011.08.027
  43. Lourenço J., Castro B. B., Machado R., Nunes B., Mendo S., Gonçalves F., Pereira R. (2010) Genetic, biochemical and individual responses of the teleost fish Carassius auratus to uranium. Archives Of Environmental Contamination And Toxicology . 58, 4, 1023-1031. (see details) ISI paper
    Link: http://www.springerlink.com/content/gu253v65q2223185/fulltext.pdf
  44. Santos, C., Caetano, T., Ferreira, S., Mendo, S. (2010) Tn5090-like class 1 integron carrying bla(VIM-2) in a Pseudomonas putida strain from Portugal. Clinical Microbiology And Infection. 16, 10, 1558-1561. (see details) ISI paper
    Link: http://dx.doi.org/10.1111/j.1469-0691.2010.03165.x
  45. Ferreira S., Toleman M., Ramalheira E., da Silva G.J., Walsh T., Mendo S. (2010) First description of Klebsiella pneumoniae clinical isolates carrying both qnrA and qnrB genes in Portugal. (in press). International Journal Of Antimicrobial Agents. 35, 6, 584-586. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.ijantimicag.2010.01.019
  46. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T., Mendo S. (2010) Carriage of qnrA1 and qnrB2, bla CTX-M15, and complex class 1 integron in a clinical multiresistant Citrobacter freundii isolate. Diagnostic Microbiology And Infectious Disease . 67, 2, 188-190. (see details) ISI paper
    Link: http://10.1016/j.diagmicrobio.2010.01.003
  47. Nogueira P., Pacheco M., Pereira M.L., Mendo S. , Rotchell J.M. (2010) Anchoring novel molecular biomarker responses to traditional responses in fish exposed to environmental contamination. Environmental Pollution . 158, 5, 1783-1790. (see details) ISI paper
  48. Domingues I, Oliveira R, Lourenço J, Grisolia C, Mendo S, Soares A (2010) Biomarkers as a tool to assess effects of chromium (VI): Comparison of responses in zebrafish early life stages and adults. Comparative Biochemistry And Physiology, Part C. 152, 338-345. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.cbpc.2010.05.010
  49. Pereira C., Guilherme S., Barroso C., Verschaeve L., Pacheco M., Mendo S. (2010) Evaluation of DNA Damage Induced by Environmental Exposure to Mercury in Liza aurata Using the Comet Assay. Archives Of Environmental Contamination And Toxicology. 58, 1, 112-122. (see details) ISI paper
    Link: http://www.springerlink.com/content/d52p024362536457/
  50. Santos, C., Caetano, T., Ferreira, S., Mendo, S. (2010) First description of the blaIMP-8 in a Pseudomonas mendocina isolated in Hospital Infante D. Pedro, Aveiro, Portugal. Research Of Microbiology. 161, 4, 305-307. (see details) ISI paper
    Link: http://www.sciencedirect.com/science/article/pii/S0923250810000574
  51. Pereira R., Marques C.R., Silva Ferreira M.J., Neves M.F.J.V., Caetano A.L., Antunes S.C., Mendo S., Gonçalves F. (2009) Phytotoxicity and genotoxicity of soils from an abandoned uranium mine area. Applied Soil Ecology. 42, 3, 209-220. (see details) ISI paper
  52. Nogueira P. R., Lourenço J., Rodriguez E., Pacheco M., Santos C., Rotchell J. M., Mendo S. (2009) Transcript profiling and DNA damage in the European eel (Anguilla anguilla L.) exposed to 7,12-dimethylbenz[a]anthracene. Aquatic Toxicology. 94, 2, 123-130. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.aquatox.2009.06.007
  53. Rodrigues A.M, Pires A., Mendo S., Quintino V. (2009) Diopatra neapolitana and Diopatra marocensis from the Portuguese coast: morphological and genetic comparison. Estuarine Coastal And Shelf Science. 85, 609-617. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.ecss.2009.10.004
  54. Pascoal, S., Creer, S., Taylor, M. I., Queiroga, H., Carvalho, G., Mendo, S. (2009) Development and application of microsatellites in Carcinus maenas: genetic differentiation between northern and central Portuguese populations. Plosone. 4, 1, e7268 (see details) ISI paper
  55. Ferreira E., Rosenthal A. , Calado V., Saraiva, J., Mendo, S. (2009) Byssochlamys nivea inactivation in pineapple juice and nectar using high pressure cycles. Journal Of Food Engineering. 95, 4, 664-669. (see details) ISI paper
    Link: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6T8J-4WSRDSR-1...
  56. Da Rocha E., Rosenthal A., Calado V., Saraiva J., Mendo S. (2009) Byssochlamys nivea inactivation in pineapple juice and nectar using high pressure cycles. Journal Of Food Engineering. 95, 4, 664-669. (see details) ISI paper
  57. Alves E., Carvalho C. M. B., Tomé J. P. C., Faustino M. A. F., Neves M .G .P. S., Tomé A. C., Cavaleiro J. A. S., Cunha Â., Mendo S., Almeida A. (2008) Photodynamic inactivation of recombinant bioluminescent Escherichia coli by cationic porphyrins under artificial and solar irradiation. Journal Of Industrial Microbiology And Biotechnology. 35, 11, 1447-1454. (see details) ISI paper
    Link: http://dx.doi.org/10.1007/s10295-008-0446-2
  58. Caetano T., Ferreira S., Mondego A.P., Correia A., Mendo S. (2007) In99 an In100 related-integron, its occurrence and prevalence in clinical Pseudomonas aeruginosa strains from Portugal. Epidemiol Infect. 135, 3, 502-504. (see details) ISI paper
    Link: DOI: 10.1017/S095026880600700X
  59. Cruz A., Caetano T., Suzuki S., Mendo S. (2007) Aeromonas veronii, a tributyltin (TBT)-degrading bacterium isolated from a estuarine environment, Ria de Aveiro in Portugal. Marine Environmental Research. 64, 639-650. (see details) ISI paper
    Link: http://www.sciencedirect.com/science?_ob=ArticleURL&_udi=B6V7H-4P6M63P-2...
  60. Nogueira P.R., Lourenço J., Mendo S., Rotchell J.M. (2006) Mutation analysis of ras gene in the liver of European eel (Anguilla anguilla L.) exposed to benzo[a]pyrene. Marine Pollution Bulletin . 12, 52, 1611-1616. (see details) ISI paper
    Link: http://dx.doi.org/10.1016/j.marpolbul.2006.05.017
  61. Sousa A., Mendo S., Barroso C.M. (2005) Imposex and organotin contamination in Nassarius reticulatus (L.) along the Portuguese coast . Applied Organometallic Chemistry. 19, 315-323. (see details) ISI paper
    Link: http://www3.interscience.wiley.com/cgi-bin/abstract/109924624/ABSTRACT?C...
  62. Sousa A., Génio L., Mendo S., Barroso C.M. (2005) Comparison of the acute toxicity of tributyltin (TBT) and copper to veliger larvae of Nassarius reticulatus (L.). Applied Organometallic Chemistry. 19, 324-328. (see details) ISI paper
    Link: http://www3.interscience.wiley.com/cgi-bin/abstract/109924625/ABSTRACT
  63. Barroso C.M., Mendo S., Moreira M.H. (2004) Organotin contamination in the mussel Mytilus galloprovincialis from Portuguese coastal waters. Marine Pollution Bulletin . 48, 1149-1153. (see details) ISI paper
  64. Mendo S., Faustino N.A., Sarmento A.C., Amado F., Moir A.J.G (2004) Purification and characterization of a new peptide antibiotic produced by a thermotolerant Bacillus licheniformis strain. Biotechnology Letters. 26, 2, 115-119. (see details) ISI paper
  65. Mendo S., Ferreira S., Nogueira P., Silva R. (2003) Tributyltin and triphenyltin toxicity on estuarine sediment bacteria. Fresenius Environmental Bulletin. 12, 11, 1361-1367. (see details) ISI paper
  66. Correia M., Boavida F., Grosso F., Salgado M.J., Melo Cristino J., Mendo S., Duarte A. (2003) Molecular characterization of a new class 3 integron in Klebsiella pneumoniae. Antimicrobial Agents And Chemotherapy. 47, 9, 2838-2843. (see details) ISI paper
  67. Mendo, S., Henriques I., Correia A., Duarte J.M. (2000) Genetic characterization of a new thermotolerant Bacillus licheniformis strain. Current Microbiology . 40, 137-139. (see details) ISI paper
  1. Cruz A, Caetano T, Suzuki S, Mendo S (2008) Corrigendum to “Aeromonas veronii, a tributyltin (TBT)-degrading bacterium isolated from an estuarine environment, Ria de Aveiro in Portugal” [Mar. Environ. Res. 64 (2007) 639–650]. Marine Environmental Research. 66, 2, 309 (see details)
  1. Hamamura N., Suzuki S., Mendo S., Barroso C., Iwata H., Tanabe S. (2010) Interdisciplinary Studies on Environmental Chemistry. (EDS.), Biological Responses to Chemical Contaminants: from Molecular to Community Level. Tokyo. TERRAPUB. 3, 978-4-88704-152-3. (see details)
  2. António Corrreia, Sónia Mendo (2001) Genética Exercícios Teórico-Práticos e Práticos. Aveiro. Universidade de Aveiro. (see details)
  1. Torres RT ., Cunha M ., Caetano T ., Mendo S ., Serrano E ., Fonseca C . (2017) Antimicrobial resistance in wild boar in Europe: present knowledge and future challenges. In: Melletti M; Meijaard E. (EDS.), Ecology, Conservation and Management of Wild Pigs and Peccaries . Cambridge. Cambridge University Press. 97811071873133. (see details)
  1. Ferreira S. (em curso) Elementos CR e a sua associação a genes de resistência. PhD Thesis. [supervisor] (see details)
  2. Santos, Tiago Filipe Melo (2015) Bioinformatics analysis of the Pedobacter sp. NL19 genome. MSc Thesis. [supervisor] (see details)
  3. Coito, Ana Margarida Barros do (2015) Bacterial communities and antibiotic resistance genes in hospital effluents and municipal wastewaters of Aveiro. MSc Thesis. [supervisor] (see details)
  4. Dias D. (2014) Presence of pathogenic bacteria and antimicrobial resistance in Portuguese wild ungulates. MSc Thesis. [supervisor] (see details)
  5. Pereira M. (2014) Directed evolution of lichenicidin. MSc Thesis. [supervisor] (see details)
  6. Rodrigues R.S.M. (2013) Transcriptome analysis of Aeromonas molluscorum Av27 following TBT exposure. MSc Thesis. (see details)
  7. Dias L.A. (2013) Search for new lantibiotics. MSc Thesis. [supervisor] (see details)
  8. Cruz A. (2012) Tributyltin (TBT) resistance in Aeromonas molluscorum Av27. PhD Thesis. (see details)
    Link: http://ria.ua.pt/handle/10773/9545
  9. Barbosa J. (2012) Lichenicidin: Regulation, Expression and bioengineering in E. coli. MSc Thesis. [supervisor] (see details)
    Link: http://ria.ua.pt/handle/10773/9548
  10. Lourenço J.I.V.L. (2012) Evaluation of genotoxic effects in humans and bioindicator species from an abandoned uranium mine area. PhD Thesis. (see details)
    Link: https://ria.ua.pt/handle/10773/9552
  11. Pascoal Sonia C.M. (2011) Nucella lapillus: imposex transcriptome analysis and phenotypic plasticity. PhD Thesis. (see details)
    Link: http://hdl.handle.net/10773/4267
  12. Caetano T. (2011) Lichenicidin biosynthesis and search for novel antibacterial peptides. PhD Thesis. [supervisor] (see details)
    Link: http://hdl.handle.net/10773/3836
  13. Silva, A. R. R. G. (2011) Toxicity and bioremediation evalution of TBT: bioassays with plants. MSc Thesis. [co-supervisor] (see details)
  14. Silva, P. V. (2011) TBT toxicity and bioremediation in soils: bioassays with invertebrates. MSc Thesis. [co-supervisor] (see details)
    Link: https://ria.ua.pt/handle/10773/7791
  15. Ferreira S. (2010) ISCR elements and their association with antibiotic resistance genes. PhD Thesis. (see details)
    Link: http://ria.ua.pt/handle/10773/974
  16. Nogueira P. (2009) Biomarcadores moleculares em peixes expostos a xenobióticos. PhD Thesis. (see details)
    Link: http://ria.ua.pt/handle/10773/967
  17. Cruz A. (2005) Identificação e clonagem dos genes implicados na resistência ao tributilestanho em bactérias marinhas. MSc Thesis. (see details)
  1. Pereira R., Correia B., Lourenço J., Marques S., Mendo S., Antunes F. (2015) Evaluation of the genotoxicity effect and antioxidant response of two nanomaterials (TiSiO4 and nanovesicles of SDS/DDAB) in Eisenia andrei. (see details)
  2. Silva A.R.R., Cardoso D.N., Cruz A., Mendo S., Soares A.M.V.M. .a.n.d. .L.o.u.r.e.i.r.o. (2015) Effects of an environmental relevant concentration of carbendazim on twelve generations of Daphnia magna . (see details)
  3. Dias D., Torres R., Fonseca C., Mendo S., Caetano T. (2015) Identification of Shiga toxin-producing E. coli (STEC) in Portuguese wild ungulates. (see details)
  4. Dias L., Caetano T., Pinheiro M., Mendo S. (2015) The lanthipeptides of B. methylotrophicus are associated with genomic islands. (see details)
  5. Barbosa J., Caetano T., Mendo S. (2015) Lichenicidin directed mutagenesis: how changes in charged amino acids affect bioactivity. (see details)
  6. Santos T., Caetano T., Mendo S. (2015) Bioinformatic analysis of the Pedobacter sp. NL19 genome. (see details)
  7. Cláudia Covas, Tânia Caetano, Andreia Cruz, and Sónia Mendo (2015) Biotechnological potential of Pedobacter portucalensis NL19 sp. nov., isolated from an abandoned uranium mine in Portugal. (see details)
  8. Silva A.R.R., Cardoso D.N., Cruz A., Lourenço J., Mendo S., Soares A. Loureiro S. (2014) Binary mixture toxicity of triclosan and carbendazim on Daphnia magna. (see details)
  9. Torres R., Dias D., Caetano T., Mendo S., Fonseca C. (2014) Antimicrobial resistance in wild boar (Sus scrofa) in Portugal. (see details)
  10. Dias D., Torres R., Fonseca C., Mendo S., Caetano T. (2014) Assessment of antibacterial resistance levels and presence of pathogenic bacteria in Portuguese wild ungulates. (see details)
  11. Lourenço J., Marques S., Vala H., Esteves F., Carvalho F., Pereira R., Mendo S. (2014) Histopathological evaluation of farm animals living near a uranium mine as sentinels of human’s exposure and health hazards. (see details)
  12. Correia B., Lourenço J., Marques S., Mendo S., Pereira R. (2014) Genotoxic effect and antioxidant response to titanium silicon oxide in Eisenia andrei. (see details)
  13. Santos, C. Viana, A. Silva, A. Mendo, S. (2014) Prevalence of colistin-resistant Acinetobacter spp. isolates in Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal. (see details)
  14. Santos, C. Ferreira, S. Ramalheira, R. Da Silva, G. Mendo, S. (2014) Carbapenem-resistant Pseudomonas aeruginosa disseminated in Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. (see details)
  15. Lourenço J., Pereira R., Pinto F., Caetano T., Silva A., Carvalheiro T., Guimarães A., Gonçalves F., Paiva A., Mendo S. (2013) Genotoxicity and immunotoxicity in a human population inhabiting nearby a deactivated uranium mine (Poster presentation). (see details)
  16. Silva P.V., Silva A.R.R., Mendo S., Loureiro S. (2013) Species sensitivity distribution of tributyltin (TBT) on terrestrial organisms. (see details)
  17. Caetano T., Suessmuth R.D., Mendo S. (2013) Insights into the lichenicidin self-protection mechanism using E. coli as model organism. (see details)
  18. Barbosa J., Caetano T., Suessmuth R.D., Mendo S. (2013) Heterologous expression of lichenicidin: improvement of the biosynthesis levels in E. coli. (see details)
  19. Barbosa J., Caetano T., Suessmuth R.D., Mendo S. (2013) Directed evolution of the lantibiotic lichenicidin. (see details)
  20. Caetano T., Barbosa J., Cruzeiro J., Suessmuth, R.D., Mendo, S. (2013) Random mutagenesis of the lantibiotic linchenicidin in E. coli. (see details)
  21. Covas C., Rodrigues R., Covas C., Cruz A., Cruz A., Cruz A., Suzuki S., Lourenço J., Lourenço J., Pereira R., Pereira R., Mendo S. , Caetano T., Caetano T., Mendo S., Mendo S. (2013) Search for novel bioactive compounds from extreme environments: biotechnological potential of two bacterial strains isolated from Portuguese abandoned uranium mine sediments. (see details)
  22. Covas C., Cruz A., Lourenco J., Pereira R., Caetano T., Mendo S. (2013) Search for novel bioactive compounds from extreme environments: biotechnological potential of two bacterial strains isolated from Portuguese abandoned uranium mine sediments. (see details)
  23. Cruz A., Henriques I., Sousa A., Correia A., Suzuki A., Anselmo, A., Mendo, S. (2013) A microcosm approach shows that Aeromonas molluscorum Av27 enhances the degradation of tributyltin (TBT) in an estuarine sediment. (see details)
  24. Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2013) Evolution of the resistance profile in non-clonal Pseudomonas aeruginosa. (see details)
  25. Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2013) Dissemination of carbapenem-resistant Pseudomonas aeruginosa in Centro Hospitalar do Baixo Vouga, Aveiro, Portugal. (see details)
  26. Santos C., Caetano T., Viana A., Silva A., Mendo S. (2013) Emerging of colistin-resistant Acinetobacter spp. isolates in Centro Hospitalar Entre Douro e Vouga, Santa Maria da Feira, Portugal. (see details)
  27. Dias L., Caetano T., Marques C., Pereira R., Mendo S. (2013) Bacillus amyloliquefaciens SMA1 isolated from an heavy metal contaminated environment produces Anti-Gram-negative compounds. (see details)
  28. Santos, C. Da Silva, G. Mendo, S. (2013) Dissemination of multidrug resistant Gram-negative bacteria within the hospital environment. (see details)
  29. Santos, C. Ramalheira, E. Mendo, S. (2013) Emergence of carbapenem resistance among Gram-negative bacteria within Centro Hospitalar do Baixo Vouga, Aveiro. (see details)
  30. Cláudia Covas, Andreia Cruz, Joana Lourenço, Ruth Pereira, Tânia Caetano, Sónia Mendo (2013) Search for novel bioactive compounds from extreme environments: biotechnological potential of two bacterial strains isolated from Portuguese abandoned uranium mine sediments. (see details)
  31. Barbosa J., Caetano T., Süssmuth R., Mendo S. (2013) Lichenicidin production: construction of expression systems. (see details)
  32. Barbosa J., Caetano T., Mendo S. (2013) Directed Evolution of the lantibiotic lichenicidin. (see details)
  33. Caetano T., Faria R., Oldach F., Suessmuth R.D., Mendo S. (2012) LicP proteolysis of the two-component lantibiotic lichenicidin using heterologous expression in Escherichia coli. (see details)
  34. Silva, P.M.P.V., Silva, A.R.R., Cruz, A., Mendo, S., Loureiro, S. (2012) Tributyltin (TBT) bioremediation evaluation in soil after Aeromonas molluscorum Av27 inoculation. (see details)
  35. Lourenço J., Pereira R., Gonçalves F., Mendo S. (2012) SSH gene expression profile of Eisenia andrei exposed in situ to a naturally contaminated soil from an abandoned uranium mine (Oral presentation). (see details)
  36. Santos, C., Ramalheira, E., Mendo, S. (2012) KPC-3 produced by Klebsiella spp. isolated from inanimate hospital surfaces in Aveiro, Central Portugal. (see details)
  37. Santos, C., Ramalheira, E., Mendo, S. (2012) Prevalence of integrons in inanimate surfaces within Hospital Infante D. Pedro, Aveiro, Central Portugal. (see details)
  38. Cruz A., Henriques I., Sousa A., Baptista I., Anselmo A. M., Almeida A., Takahashi S., Tanabe S., Correia A., Suzuki S., Mendo S. (2012) Bioremediation of tributyltin (TBT) by Aeromonas molluscorum Av27. (see details)
  39. Oldach F, Caetano T., Kuthning A., Al Toma R., Krawczyk J.M., Mosker E., Budisa N., Mendo S., Suessmuth R.D. (2012) Heterologous Expression of the Lantibiotic Lichenicidin in E.coli and generation of new congeners by introducing non-natural amino acids. (see details)
  40. Cruz A., Rodrigues R., Barroso C., Suzuki S., Mendo S. (2012) Aeromonas molluscorum Av27 transcriptome analysis: future applications for TBT detection and remediation. (see details)
  41. Silva, A.R.R., Silva, P.M.P.V., Mendo, S., Loureiro, S., (2012) Toxicity of Tributyltin (TBT) on terrestrial invertebrates and plants. (see details)
  42. Barbosa J., Cruzeiro J., Süssmuth R., Caetano T., Mendo S. (2012) Lichenicidin Bioengineering: peptides with changed bioactivity. (see details)
  43. Caetano T., Barbosa J., Cruzeiro J., Jorge R., Süssmuth R., Mendo S. (2012) Search for new lantibiotics: case study of lichenicidin. (see details)
  44. Barbosa J., Caetano T., Süssmuth R., Mendo S. (2012) Lichenicidin: heterologous expression and biosynthesis comparison. (see details)
  45. Lourenço J., Pereira R., Silva A., Carvalho F., Oliveira J., Malta M., Paiva A., Gonçalves F., Mendo S. (2011) In situ and laboratorial assays using earthworms for the risk assessment of uranium mines. (see details)
  46. Lourenço J., Pereira R., Silva A., Carvalho F., Oliveira J., Malta M., Paiva A., Gonçalves F., Mendo S. (2011) Earthworms’ in situ exposure and evaluation of genotoxicity endpoints to assess the toxicity of uranium mining wastes. (see details)
  47. Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Mobile genetic elements: a comparative study of their presence in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal, in 2005 and 2008. (see details)
  48. Santos C., Lima C, Ramalheira E., Caetano T., Mendo S. (2011) Tracking the presence of class 1 integrons in Gram-negative bacteria collected from surfaces and biological samples in Hospital Infante D. Pedro, Aveiro, central Portugal. (see details)
  49. Santos, C. Diaz, R. Ramalheira, E. Mendo, S. (2011) Antibiotic resistance genes detected in Enterobacteriaceae that colonize inanimate surfaces. (see details)
  50. Santos, C. Ramalheira, E. Caetano, T. Mendo, S. (2011) In37 – a complex class 1 integron found in different species from hospital surfaces / furniture. (see details)
  51. Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Prevalence of beta-lactamase enzymes in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal. (see details)
  52. Lourenço J., Pereira R., Silva A. C., Morgado J. M., Carvalho F., Oliveira J., Malta M., Paiva A., Mendo S., Gonçalves F. (2010) Measurement of Genotoxicity Endpoints in the Earthworm Reproduction Assay. (see details)
  53. Pereira R., Ksibi M., Haddioui A., Römbke J. , Sousa J.P. , Gonçalves F., Marques C., Frankenbach S., Silva C., Mistiri A. , Hentati O. , Gomes N., Mendo S. (2010) Research on bioremediation of mining areas as part of a NATO Science for Peace Project. (see details)
  54. Santos C., Caetano T., Ramalheira H., Ferreira S., Mendo S. (2010) Occurrence and dissemination of genetic resistance determinants among Gram-negative isolates collected from inanimate surfaces in a hospital in Aveiro, Portugal. (see details)
  55. A. Paradela, S. Ferreira, E. Ramalheira, S. Mendo (2010) Evaluation of phenotypic methods for detection of AmpC producers among Klebsiella pnemoniae clinical isolates. (see details)
  56. Ferreira S., Santos, C., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of class 1 integrons in Klebsiella pneumoniae Isolates in a hospital in Aveiro, central Portugal. (see details)
  57. Ferreira S., Tortas L., Ramalheira E., Mendo S. (2010) Surveillance of Pseudomonas aeruginosa isolates resistant to carbapenems during 7 years period (2003-2009) in Aveiro. (see details)
  58. Diaz R., Ferreira S., Freitas S., Mendo S. (2010) Prevalence of sul genes in E.coli causing urinary tract infections in the community. (see details)
  59. Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of genetic resistant determinants among Gram negative isolates collected form inanimate surfaces in the hospital Infante D. Pedro Aveiro, central Portugal. (see details)
  60. Pascoal S., Carvalho G., Hughes R., Cossins A., Ashelford K., Olohan L., Fang Y., Barroso C., Mendo S., Creer S. (2010) Environmental genomics of the marine gastropod Nucella lapillus in response to organotin pollution. (see details)
  61. Santos C, Caetano T, Ramalheira E, Ferreira S, Mendo S (2009) Occurrence and characterization of class 1 integrons from isolates collected in a hospital’s sanitary facility in Aveiro, Portugal. (see details)
  62. Lourenço J., Pereira R., Silva A. C., Morgado J. M., Carvalho F., Oliveira J., Malta M., Paiva A., Mendo S., Gonçalves F. (2009) New Genotoxic Endpoints for the Earthworm Reproduction Assay. (see details)
  63. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Ocurrence of blaCTX-M-15 gene in multidrug-resistant Citrobacter freundii. (see details)
  64. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) First description of a multidrug-resistant Citrobacter freundii carrying both qnrA and qnrB in Aveiro, Portugal. (see details)
  65. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Prevalence of ampC β-lactamase genes in Enterobacteriaceae clinical isolates from Aveiro, Portugal. (see details)
  66. Ferreira S., Paradela A., Velez J., Ramalheira E., Mendo S. (2009) Prevalence of ampC b-lactamase genes in Enterobacteriaceae clinical isolates from Aveiro, Portugal. (see details)
  67. Ferreira S., Paradela A., Velez J., Ramalheira E., Mendo S. (2009) First description of a multidrug-resistant Citrobacter freundii carrying both qnrA and qnrB in Aveiro, Portugal. (see details)
  68. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T., Mendo S. (2009) Ocurrence of blaCTX-M-15 gene in multidrug-resistant Citrobacter freundii. (see details)
  69. Lourenço J., Castro B.B., Machado R., Mendo S., Gonçalves F., Pereira R. (2008) Assessment of uranium genotoxicity by comet assay in the teleost fish Carassius auratus. (see details)
  70. Caetano T., Leal P. M., Mendo S. (2008) Novel antistaphylococcal peptide produced by Bacillus licheniformis. (see details)
  71. Caetano T., Ferreira S., Tortas L., Cerveira F., Ramalheira E., Mendo S. (2008) Prevalence of In99 among Pseudomonas aeruginosa isolates from a central region of Portugal (Aveiro) since 2003. (see details)
  72. Caetano T., Howe R.A., Hawrani A., Dempsey C., Mendo S., Walsh T.R. (2008) Comparison of RTA3 and Colistin for Selection and Stability of Resistant Mutants with Clinical and Type Strains of Pseudomonas, Acinetobacter, and Escherichia Coli. (see details)
  73. Caetano T., Howe R.A., Hawrani A., Dempsey C., Mendo S., Walsh T.R. (2008) Activity of RTA-3 Against Multi-Drug Resistant Pseudomonas, Acinetobacter and Enterobacteriaceae Possessing Defined Genotypes. (see details)
  74. Cruz A., Suzuki S., Mendo S. (2008) Different genes coding for tributyltin (TBT) resistance in Aeromonas spp. (see details)
  75. Pereira A., Ferreira S., Paradela A., Cerveira F., Ramalheira E., Mendo S. (2008) First report of plasmid-mediated quinolone resistance determinants qnrA, qnrB and qnrS among Gram-negative clinical isolates from Aveiro, Portugal. (see details)
  76. Pereira A., Ferreira S., Paradela A., Cerveira F., Ramalheira E., Mendo S. (2008) Prevalence of In99 among Pseudomonas aeruginosa isolates from a central region of Portugal (Aveiro) since 2003. (see details)
  77. Ferreira S., Paradela A., Ramalheira E., Walsh T.R., Mendo S. (2008) First description of a Klebsiella pneumoniae carrying both qnrA and qnrB genes in Aveiro, Portugal. (see details)
  78. Cruz A., Suzuki S., Mendo S. (2008) Aeromonas veronii, a TBT degrading bacterium isolated from an estuarine environment, Ria de Aveiro in Portugal. (see details)
  79. Pereira S., Domingues S., Mendo S., Duarte A., da Silva G (2008) Occurrence and molecular characterization of Class 1 integrons in Acinetobacter baumanii clinical isolates collected from 2005 to 2006 in Portugal. (see details)
  80. Pascoal S., Creer S. , Hughes R., Miguez C., Mendo S., Carvalho G. (2008) Environmental genomics of the marine gastropod Nucella lapillus in response to organotin pollution. (see details)
  81. Cruz A., Nonaka L., Suzuki S., Mendo S. (2007) Aeromonas veronii, tributyltin (TBT) resistant bacteria: future development of a biosensor for TBT detection and bioremediation. (see details)
  82. Ferreira S., Ferreira S., Toleman M. A. , Toleman M., Walsh T.R., Walsh T., Mendo S., Mendo S. (2007) Occurrence and diversity of genetic resistance determinants among Enterobacteriaceae clinical isolates in Aveiro, Portugal. (see details)
  83. Ferreira S., Walsh T.R., Mendo S. (2007) Outbreak of a nosocomial carbapenem resistant Acinetobacter baumannii in Aveiro, Portugal. (see details)
  84. Ferreira S., Ramalheira E., Mendo S. (2007) Bactérias multirresistentes: um problema crescente?. (see details)
  85. Ferreira S., Pereira A., Paradela A., Tortas L., Mendo S., Ramalheira E. (2007) Diagnóstico da tuberculose: métodos moleculares. (see details)
  86. Cruz A., Nonaka L., Domingos A., Suzuki S., Mendo S. (2006) Tributyltin (TBT) resistance in Aeromonas veronii: Isolation of gene(s) and protein(s) involved in TBT resistance. (see details)
  87. Sousa A.C., Mendo S., Barroso C.M. (2006) Comparison of the acute toxicity of copper and tributyltin (TBT) to veliger larvae of Nassarius reticulatus. (see details)
  88. Pascoal S., Queiroga H., Mendo S. (2006) Development and application of microsatellites as a tool to study Carcinus maenas genetic flow along the Portuguese coast. (see details)
  89. Cruz A., Caetano T., Mendo S. (2005) Mechanisms involved in resistance/tolerance to TBT and other antifouling compounds by marine bacteria. (see details)
  90. Sousa A., Mendo S., Barroso C.M. (2005) Imposex and organotin contamination in Nassarius reticulatus (L.) along the portuguese coast. (see details)
  91. Sousa A., Génio L., Mendo S., Barroso C.M. (2005) Acute toxicity of tributyltin (TBT) to veliger larvae of Nassarius reticulatus. (see details)
  92. Ferreira S., Walsh T.R., Mendo S. (2005) Novel gyrB and parE mutations detected in the quinolone-resistance-determining-region of clinical quinolone resistant Pseudomonas aeruginosa. (see details)
  93. Ferreira S., Mendo S. (2005) Molecular genotyping as a tool for identifying dissemination of quinolone resistant Pseudomonas aeruginosa isolates. (see details)
  94. Barroso C.M., Mendo S. (2005) History of organotin pollution in Portuguese coastal waters: analysis of exposure potential, biological effects and future Ecological Risk Assessment approach. (see details)
  95. Ferreira S., Mendo S. (2004) Molecular genotyping of Pseudomonas aeruginosa clinical isolates resistant to quinolones: detection of mutations in the gyr genes. (see details)
  96. Joana Barbosa, Tânia Caetano, Sónia Mendo Lichenicidin directed mutagenesis: how changes in charged amino acids affect bioactivity. (see details)
  97. Mendo, Sonia Transcriptomes analysis of Aeromonas molluscorum Av27 cells exposed to tributyltin (TBT): unravelling the effects from the molecular level to the organism. (see details)
  1. Lourenco, J., Marques, S., Vala, H., Esteves, F., Carvalho, F., Pereira, R., Mendo, S. (2014) Histopathological evaluation of farm animals living near a uranium mine as sentinels of human’s exposure and health hazards , in: VIRCHOWS ARCHIV. SPRINGER 233 SPRING ST, NEW YORK, NY 10013 USA, pp. S284–S284. (see details)
  2. Correia, B., Lourenço, J., Marques, S., Mendo, S., Pereira, R. (2014) Genotoxic effect and antioxidant response to titanium silicon oxide in Eisenia andrei. Toxicol. Lett. 229, Supplement, S201. . (see details)
  3. Santos, C. Ramalheira, R. Da Silva, G. Mendo, S. (2014) Colonization of the hospital environment by multidrug resistant Gram-negative bacteria. (see details)
  4. Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Prevalence of beta-lactamase enzymes in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal; Clinical Microbiology and Infection, vol. 17, suppl. 4, page S142. (see details)
    Link: http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03558.x/pdf
  5. Santos C., Diaz R., Ramalheira E., Caetano T., Mendo S. (2011) Mobile genetic elements: a comparative study of their presence in bacteria from inanimate surfaces in Hospital Infante D. Pedro, Aveiro, central Portugal, in 2005 and 2008; Clinical Microbiology and Infection, vol. 17, suppl. 4, page S. (see details)
    Link: http://onlinelibrary.wiley.com/doi/10.1111/j.1469-0691.2011.03558.x/pdf
  6. Lourenço J., Silva A., Carvalho F., Oliveira J., Malta M., Mendo S., Gonçalves F., Pereira R. (2011) Are histopathological endpoints useful for the evaluation of natural soils contaminated by metals and radionuclides? Toxicol Lett 205 (Supplement 1):S131-S131. (see details)
  7. Lourenço J., Pereira R., Silva A. C., Morgado J. M., Oliveira J., Carvalho F., Malta M., Paiva A., Mendo S., Gonçalves F. (2010) Measurement of Genotoxic Endpoints in Earthworms Exposed to Radioactive Wastes from an Abandoned Uranium Mine. Interdisciplinary Studies on Environmental Chemistry — Biological Responses to Contaminants, 2 - 4 September 2009, Aveiro, Portugal (Proceedings) in Interdisciplinary Studies on Environmental Chemistry — Biological Responses to Contaminants pp 219-225. (see details)
  8. Cruz A., Henriques I., Correia A., Suzuki S., Mendo S. (2010) Aeromonas molluscorum Av27: A Potential Natural Tool for TBT Decontamination. Proceeding in Interdisciplinary Studies on Environmental Chemistry — Biological Responses to Contaminants, September 2-4th. Aveiro, Portugal. (see details)
  9. Cruz A., Nonaka L., Domingos A., Suzuki S., Mendo S. (2010) Tributyltin (TBT) resistance in Aeromonas veronii: Isolation of gene(s) and protein(s) involved in TBT resistance. Proceeding in Coastal Marine Environmental Research, November 17-19th. Matsuyama, Japan. (see details)
  10. Ferreira S., Santos C., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of class 1 integrons in Klebsiella pneumoniae Isolates in a hospital in Aveiro, central Portugal-Clinical Microbiology and Infection vol16, Suppl2. (see details)
  11. Ferreira S., Santos C., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of class 1 integrons in Klebsiella pneumoniae Isolates in a hospital in Aveiro, central Portugal. 2010. Clinical Microbiology and Infection vol16, Suppl2. (see details)
  12. Ferreira S., Tortas, L., Ramalheira E., Mendo S. (2010) Surveillance of Pseudomonas aeruginosa isolates resistant to carbapenems during 7 years period (2003-2009) in Aveiro. 2010. Clinical Microbiology and Infection vol16, Suppl.2. (see details)
  13. Diaz R., Ferreira S., Freitas A., Mendo S. (2010) Prevalence of sul genes in Escherichia coli causing urinary tract infections in the community. Clinical Microbiology and Infection vol16, Suppl2. (see details)
  14. Paradela A., Ferreira S., Ramalheira E. , Mendo S. (2010) Evaluation of phenotypic methods for detection of AmpC producers among Klebsiella pneumoniae clinical isolates; Clinical Microbiology and Infection vol16, Suppl2. (see details)
  15. Santos C., Caetano T., Ferreira S., Ramalheira E., Mendo S. (2010) Occurrence and dissemination of genetic resistance determinants among Gram negative isolates collected from inanimate surfaces in the Hospital Infante D. Pedro, Aveiro, central Portugal; Clinical Microbiology and Infection vol16, Suppl2. (see details)
  16. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Ocurrence of blaCTX-M-15 gene in multidrug-resistant Citrobacter freundii. Proceeding in Supplement to Clinical Microbiology and Infection Vol 15, Suppl. 4. (see details)
  17. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) First description of a multidrug-resistant Citrobacter freundii carrying both qnrA and qnrB in Aveiro, Portugal. Proceeding in Supplement to Clinical Microbiology and Infection, Vol 15, Suppl. 4. (see details)
  18. Ferreira S., Paradela A., Velez J., Ramalheira E., Walsh T.R., Mendo S. (2009) Prevalence of ampC β-lactamase genes in Enterobacteriaceae clinical isolates from Aveiro, Portugal. 2009. Proceeding in Clinical Microbiology and Infection, Vol 15, Suppl. 4. (see details)
  19. Santos C., Caetano T., Ramalheira R., Ferreira S., Mendo S. (2009) Occurrence and characterization of class 1 integrons from isolates collected in a hospital’s sanitary facility in Aveiro, Portugal; Clinical Microbiology and Infection vol15, Suppl3, Page S425. (see details)
  20. Caetano T., Ferreira S., Tortas L., Cerveira F., Ramalheira E., Mendo S. (2008) Prevalence of In99 among Pseudomonas aeruginosa isolates from a central region of Portugal (Aveiro) since 2003. Proceeding in Supplement to Clinical Microbiology and Infection Vol.14, Suppl. 7. (see details)
  21. Cruz A., Nonaka L., Suzuki S., Mendo S. (2007) Aeromonas veronii, tributyltin (TBT) resistant bacteria: future development of a biosensor for TBT detection and bioremediation. Proceeding in XIII Symposium in Pesticide Chemistry, September 3-6th. Piacenza, Italy. pp. 807-811. (see details)
  22. Ferreira S., Paradela A., Ribau A., Ramalheira E., Mendo S. (2007) Detection of extended-spectrum beta-lactamases, including the CTX-M-type enzymes, among Enterobacteriaceae using VITEK 2 system and the Advanced Expert System. Proceeding in Supplement to Clinical Microbiology and Infection Vol.13, Suppl. 1. (see details)
  23. Ferreira S., Toleman M. A., Walsh T.R., Mendo S. (2007) “Occurrence and diversity of genetic resistance determinants among Enterobacteriaceae clinical isolates in Aveiro, Portugal. Proceeding in Supplement to Clinical Microbiology and Infection Vol.13, Suppl. 1. (see details)