F Rosário, IF Duarte, RJB Pinto, C Santos, PHM Hoet, H Oliveira (2021) Biodistribution and pulmonary metabolic effects of silver nanoparticles in mice following acute intratracheal instillations.
Environmental Science And Pollution Research, 28
, (2), 2301-2314.
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D.F.S. Fonseca, C. Vilela, R.J.B. Pinto, V. Bastos, H. Oliveira, J. Catarino, P. Faísca, C. Rosado, A.J.D. Silvestre, C.S.R. Freire (2021) Bacterial nanocellulose-hyaluronic acid microneedle patches for skin applications: In vitro and in vivo evaluation.
Materials Science And Engineering: C, 118
111350.
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Cynthia Kembuan, Helena Oliveira, Christina Graf (2021) Effect of different silica coatings on the toxicity of upconversion nanoparticles on RAW 264.7 macrophage cells.
Beilstein Journal Of Nanotechnology, 12
35-48.
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Diogo Marinheiro, Bárbara JML Ferreira, Párástu Oskoei, Helena Oliveira, Ana L Daniel-da-Silva (2021) Encapsulation and Enhanced Release of Resveratrol from Mesoporous Silica Nanoparticles for Melanoma Therapy.
Materials, 14
, (6), 1382.
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Vicente E.D., Figueiredo D., Gonçalves C., Lopes I., Oliveira H., Kováts N., Pinheiro T., Alves C.A. (2021) In vitro toxicity of indoor and outdoor PM10 from residential wood combustion.
Science Of The Total Environment, 782
146820.
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Cicuendez M., Fernandes M., Ayan-Varela M., Oliveira H., Feito M.J., Diez-Orejas R., Paredes J.I., Villar-Rodil S., Vila M., Portoles M.T., Duarte I.F. (2020) Macrophage inflammatory and metabolic responses to graphene-based nanomaterials differing in size and functionalization.
COLLOIDS AND SURFACES B-BIOINTERFACES, 186
.
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Matos R.C., Oliveira H., Fonseca H.M.A.C., Morais S., Sharma B., Santos C., Pereira M.D. (2020) Comparative Cr, As and CCA induced Cytostaticity in mice kidney: A contribution to assess CCA toxicity.
ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY, 73
.
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Pinto R.J.B., Bispo D., Vilela C., Botas A.M.P., Ferreira R.A.S., Menezes A.C., Campos F., Oliveira H., Abreu M.H., Santos S.A.O., Freire C.S.R. (2020) One-Minute Synthesis of Size-Controlled Fucoidan-Gold Nanosystems: Antitumoral Activity and Dark Field Imaging.
MATERIALS, 13
, (5), .
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Debasu M.L., Oliveira H., Rocha J., Carlos L.D. (2020) Colloidal (Gd0.98Nd0.02)(2)O-3 nanothermometers operating in a cell culture medium within the first and second biological windows.
JOURNAL OF RARE EARTHS, 38
, (5), 483-491.
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Barra A., Alves Z., Ferreira N.M., Martins M.A., Oliveira H., Ferreira L.P., Cruz M.M., Carvalho M.D., Neumayer S.M., Rodriguez B.J., Nunes C., Ferreira P. (2020) Biocompatible chitosan-based composites with properties suitable for hyperthermia therapy.
JOURNAL OF MATERIALS CHEMISTRY B, 8
, (6), 1256-1265.
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Carvalho J.P.F., Silva A.C.Q., Bastos V., Oliveira H., Pinto R.J.B., Silvestre A.J.D., Vilela C., Freire C.S.R. (2020) Nanocellulose-Based Patches Loaded with Hyaluronic Acid and Diclofenac towards Aphthous Stomatitis Treatment.
NANOMATERIALS, 10
, (4), .
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Fonseca D.F.S., Costa P.C., Almeida I.F., Dias-Pereira P., Correia-Sa I., Bastos V., Oliveira H., Duarte-Araujo M., Morato M., Vilela C., Silvestre A.J.D., Freire C.S.R. (2020) Pullulan microneedle patches for the efficient transdermal administration of insulin envisioning diabetes treatment.
CARBOHYDRATE POLYMERS, 241
.
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Fonseca D.F.S., Costa P.C., Almeida I.F., Dias-Pereira P., Correia-Sa I., Bastos V., Oliveira H., Vilela C., Silvestre A.J.D., Freire C.S.R. (2020) Swellable Gelatin Methacryloyl Microneedles for Extraction of Interstitial Skin Fluid toward Minimally Invasive Monitoring of Urea.
MACROMOLECULAR BIOSCIENCE,
.
Ver mais
Carrola J., Bastos V., Daniel-da-Silva A.L., Gil A.M., Santos C., Oliveira H., Duarte I.F. (2020) Macrophage Metabolomics Reveals Differential Metabolic Responses to Subtoxic Levels of Silver Nanoparticles and Ionic Silver.
EUROPEAN JOURNAL OF INORGANIC CHEMISTRY, 2020
, (19), 1867-1876.
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Ângela R Guerra, Ana F Paulino, Maria M Castro, Helena Oliveira, Maria F Duarte, Iola F Duarte (2020) Triple Negative Breast Cancer and Breast Epithelial Cells Differentially Reprogram Glucose and Lipid Metabolism upon Treatment with Triterpenic Acids.
Biomolecules, 10
, (8), 1163.
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Fonseca DFS, Carvalho JPF. Bastos V2, Oliveira H, Moreirinha C, Almeida A, Silvestre AJD, Vilela C, Freire CSR (2020) Antibacterial Multi-Layered Nanocellulose-Based Patches Loaded with Dexpanthenol for Wound Healing Applications. .
Nanomaterials,
.
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Cicuendez M., Silva V.S., Santos J., Coimbra A., Oliveira H., Ayan-Varela M., Paredes J.I., Villar-Rodil S., Vila M. (2019) MoS2 flakes stabilized with DNA/RNA nucleotides: In vitro cell response.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 100
11-22.
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Oliveira H., Bednarkiewicz A., Falk A., Frohlich E., Lisjak D., Prina-Mello A., Resch S., Schimpel C., Vrcek I.V., Wysokinska E., Gorris H.H. (2019) Critical Considerations on the Clinical Translation of Upconversion Nanoparticles (UCNPs): Recommendations from the European Upconversion Network (COST Action CM1403).
ADVANCED HEALTHCARE MATERIALS, 8
, (1), .
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Monteiro C., Santos C., Bastos V., Oliveira H. (2019) Cr(VI)-induced genotoxicity and cell cycle arrest in human osteoblast cell line MG-63.
JOURNAL OF APPLIED TOXICOLOGY, 39
, (7), 1057-1065.
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Macario I.P.E., Oliveira H., Menezes A.C., Ventura S.P.M., Pereira J.L., Goncalves A.M.M., Coutinho J.A.P., Goncalves F.J.M. (2019) Cytotoxicity profiling of deep eutectic solvents to human skin cells.
SCIENTIFIC REPORTS, 9
.
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Santos M., Oliveira H., Pereira J.L., Pereira M.J., Goncalves F.J.M., Vidal T. (2019) Flow cytometry analysis of low/high DNA content (LNA/HNA) bacteria as bioindicator of water quality evaluation.
ECOLOGICAL INDICATORS, 103
774-781.
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Vilela C., Oliveira H., Almeida A., Silvestre A.J.D., Freire C.S.R. (2019) Nanocellulose-based antifungal nanocomposites against the polymorphic fungus Candida albicans.
CARBOHYDRATE POLYMERS, 217
207-216.
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Santos M., Peixoto S., Pereira J.L., Luis A.T., Henriques I., Goncalves F.J.M., Pereira M.J., Oliveira H., Vidal T. (2019) Using flow cytometry for bacterioplankton community analysis as a complementary tool to Water Framework Directive to signal putatively impacted sites.
SCIENCE OF THE TOTAL ENVIRONMENT, 695
.
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Rodríguez-Luna A., Ávila-Román J., Oliveira H., Motilva V., Talero E. (2019) Fucoxanthin and rosmarinic acid combination has anti-inflammatory effects through regulation of NLRP3 inflammasome in UVB-exposed HaCaT keratinocytes.
Marine Drugs , 17
, (8), 451.
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Menezes A.C., Carvalheiro M., de Oliveira J.M.P.F., Ascenso A., Oliveira H. (2018) Cytotoxic effect of the serotonergic drug 1-(1-Naphthyl)piperazine against melanoma cells.
TOXICOLOGY IN VITRO, 47
72-78.
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de Oliveira J.M.P.F., Pacheco A.R., Coutinho L., Oliveira H., Pinho S., Almeida L., Fernandes E., Santos C. (2018) Combination of etoposide and fisetin results in anti-cancer efficiency against osteosarcoma cell models.
ARCHIVES OF TOXICOLOGY, 92
, (3), 1205-1214.
Ver mais
Dias M.C., Pinto D.C.G.A., Correia C., Moutinho-Pereira J., Oliveira H., Freitas H., Silva A.M.S., Santos C. (2018) UV-B radiation modulates physiology and lipophilic metabolite profile in Olea europaea.
JOURNAL OF PLANT PHYSIOLOGY, 222
39-50.
Ver mais
Carrola J., Pinto R.J.B., Nasirpour M., Freire C.S.R., Gil A.M., Santos C., Oliveira H., Duarte I.F. (2018) NMR Metabolomics Reveals Metabolism-Mediated Protective Effects in Liver (HepG2) Cells Exposed to Subtoxic Levels of Silver Nanoparticles.
JOURNAL OF PROTEOME RESEARCH, 17
, (4), 1636-1646.
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Santos C.I.M., Goncalves G., Cicuendez M., Mariz I., Silva V.S., Oliveira H., Campos F., Vieira S.I., Marques P.A.A.P., Macoas E.M.S., Neves M.G.P.M.S., Martinho J.M.G. (2018) Biocompatible hybrids based on nanographene oxide covalently linked to glycolporphyrins: Synthesis, characterization and biological evaluation.
CARBON, 135
202-214.
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Cicuendez M., Flores J., Oliveira H., Portoles M.T., Vallet-Regi M., Vila M., Duarte I.F. (2018) Metabolomic response of osteosarcoma cells to nanographene oxide-mediated hyperthermia.
MATERIALS SCIENCE & ENGINEERING C-MATERIALS FOR BIOLOGICAL APPLICATIONS, 91
340-348.
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Rosario F., Hoet P., Nogueira A.J.A., Santos C., Oliveira H. (2018) Differential pulmonary in vitro toxicity of two small-sized polyvinylpyrrolidone-coated silver nanoparticles.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 81
, (15), 675-690.
Ver mais
Araujo A.R.D., Melo T., Maciel E.A., Pereira C., Morais C.M., Santinha D.R., Tavares J.F., Oliveira H., Jurado A.S., Costa V., Domingues P., Domingues M.R.M., Santos M.A.S. (2018) Errors in protein synthesis increase the level of saturated fatty acids and affect the overall lipid profiles of yeast.
PLOS ONE, 13
, (8), .
Ver mais
Monteiro C., de Oliveira J.M.P.F., Pinho F., Bastos V., Oliveira H., Peixoto F., Santos C. (2018) Biochemical and transcriptional analyses of cadmium-induced mitochondrial dysfunction and oxidative stress in human osteoblasts.
JOURNAL OF TOXICOLOGY AND ENVIRONMENTAL HEALTH-PART A-CURRENT ISSUES, 81
, (15), 705-717.
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Monteiro C., Sario S., Mendes R., Mariz-Ponte N., Silva S., Oliveira H., Bastos V., Santos C., Dias M.C. (2018) Bridging a Gap between Cr(VI)-Induced Oxidative Stress and Genotoxicity in Lettuce Organs after a Long-Term Exposure.
INTERNATIONAL JOURNAL OF AGRONOMY,
.
Ver mais
Ramos P.A.B., Guerra A.R., Guerreiro O., Santos S.A.O., Oliveira H., Freire C.S.R., Silvestre A.J.D., Duarte M.F. (2017) Antiproliferative Effects of Cynara cardunculus L. var. altilis (DC) Lipophilic Extracts.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES, 18
, (1), .
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Coutinho L., Oliveira H., Pacheco A.R., Almeida L., Pimentel F., Santos C., de Oliveira J.M.P.F. (2017) Hesperetin-etoposide combinations induce cytotoxicity in U2OS cells: Implications on therapeutic developments for osteosarcoma.
DNA REPAIR, 50
36-42.
Ver mais
Silva S., Silva P., Oliveira H., Gaivao I., Matos M., Pinto-Carnide O., Santos C. (2017) Pb low doses induced genotoxicity in Lactuca sativa plants.
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 112
109-116.
Ver mais
Lamego I., Marques M.P.M., Duarte I.F., Martins A.S., Oliveira H., Gil A.M. (2017) Impact of the Pd(2)Spermine Chelate on Osteosarcoma Metabolism: An NMR Metabolomics Study.
JOURNAL OF PROTEOME RESEARCH, 16
, (4), 1773-1783.
Ver mais
Saidi L., Vilela C., Oliveira H., Silvestre A.J.D., Freire C.S.R. (2017) Poly(N-methacryloyl glycine)/nanocellulose composites as pH-sensitive systems for controlled release of diclofenac.
CARBOHYDRATE POLYMERS, 169
357-365.
Ver mais
Silva S., Craveiro S.C., Oliveira H., Calado A.J., Pinto R.J.B., Silva A.M.S., Santos C. (2017) Wheat chronic exposure to TiO2-nanoparticles: Cyto- and genotoxic approach.
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 121
89-98.
Ver mais
Silva S., Oliveira H., Silva A.M.S., Santos C. (2017) The cytotoxic targets of anatase or rutile plus anatase nanoparticles depend on the plant species.
BIOLOGIA PLANTARUM, 61
, (4), 717-725.
Ver mais
Bastos V., Duarte I.F., Santos C., Oliveira H. (2017) A study of the effects of citrate-coated silver nanoparticles on RAW 264.7 cells using a toolbox of cytotoxic endpoints.
JOURNAL OF NANOPARTICLE RESEARCH, 19
, (5), .
Ver mais
Bastos V., Ferreira-de-Oliveira J.M.P., Carrola J., Daniel-da-Silva A.L., Duarte I.F., Santos C., Oliveira H. (2017) Coating independent cytotoxicity of citrate- and PEG-coated silver nanoparticles on a human hepatoma cell line.
JOURNAL OF ENVIRONMENTAL SCIENCES, 51
191-201.
Ver mais
Bastos V., Duarte I.F., Santos C., Oliveira H. (2017) Genotoxicity of citrate-coated silver nanoparticles to human keratinocytes assessed by the comet assay and cytokinesis blocked micronucleus assay.
ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH, 24
, (5), 5039-5048.
Ver mais
Menezes A.C., Raposo S., Simoes S., Ribeiro H., Oliveira H., Ascenso A. (2016) Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors.
MOLECULAR NEUROBIOLOGY, 53
, (2), 1145-1164.
Ver mais
Carrola J., Bastos V., de Oliveira J.M.P.F., Oliveira H., Santos C., Gil A.M., Duarte I.F. (2016) Insights into the impact of silver nanoparticles on human keratinocytes metabolism through NMR metabolomics.
ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 589
53-61.
Ver mais
Ascenso A., Pedrosa T., Pinho S., Pinho F., de Oliveira J.M.P.F., Marques H.C., Oliveira H., Simoes S., Santos C. (2016) The Effect of Lycopene Preexposure on UV-B-Irradiated Human Keratinocytes.
OXIDATIVE MEDICINE AND CELLULAR LONGEVITY,
.
Ver mais
Silva S., Oliveira H., Craveiro S.C., Calado A.J., Santos C. (2016) Pure anatase and rutile plus anatase nanoparticles differently affect wheat seedlings.
CHEMOSPHERE, 151
68-75.
Ver mais
Debasu M.L., Brites C.D.S., Balabhadra S., Oliveira H., Rocha J., Carlos L.D. (2016) Nanoplatforms for Plasmon-Induced Heating and Thermometry.
CHEMNANOMAT, 2
, (6), 520-527.
Ver mais
Nunes S., Santos C., Moutinho-Pereira J., Correia C., Oliveira H., de Oliveira J.M.F., Pereira V.T., Almeida T., Marum L., Dias M.C. (2016) Physiological characterization and true-to-typeness evaluation of in vitro and ex vitro seedlings of Pinus elliottii: A contribution to breeding programs.
PLANT PHYSIOLOGY AND BIOCHEMISTRY, 107
222-227.
Ver mais
Bastos V., de Oliveira J.M.P.F., Brown D., Jonhston H., Malheiro E., Daniel-da-Silva A.L., Duarte I.F., Santos C., Oliveira H. (2016) The influence of Citrate or PEG coating on silver nanoparticle toxicity to a human keratinocyte cell line.
TOXICOLOGY LETTERS, 249
29-41.
Ver mais
Rosario F., Hoet P., Santos C., Oliveira H. (2016) Death and cell cycle progression are differently conditioned by the AgNP size in osteoblast-like cells.
TOXICOLOGY, 368
103-115.
Ver mais
Carrola J., Bastos V., Jarak I., Oliveira-Silva R., Malheiro E., Daniel-da-Silva A.L., Oliveira H., Santos C., Gil A.M., Duarte I.F. (2016) Metabolomics of silver nanoparticles toxicity in HaCaT cells: structure-activity relationships and role of ionic silver and oxidative stress.
NANOTOXICOLOGY, 10
, (8), 1105-1117.
Ver mais
Bastos V., Brown D., Johnston H., Daniel-da-Silva A.L., Duarte I.F., Santos C., Oliveira H. (2016) Inflammatory responses of a human keratinocyte cell line to 10 nm citrate- and PEG-coated silver nanoparticles.
JOURNAL OF NANOPARTICLE RESEARCH, 18
, (7), .
Ver mais
Josee M.D.S., Corredoira E., Oliveira H., Santos C. (2015) Cryopreservation of somatic embryos of Alnus glutinosa (L.) Gaertn. and confirmation of ploidy stability by flow cytometry.
PLANT CELL TISSUE AND ORGAN CULTURE, 123
, (3), 489-499.
Ver mais
Ferreira de Oliveira JMP, Costa M, Pedrosa T, Pinto P, Remedios C, Oliveira H, Pimentel F, Almeida L, Santos C (2014) Sulforaphane Induces Oxidative Stress and Death by p53-Independent Mechanism: Implication of Impaired Glutathione Recycling.
Plos One, 9
, (3), e92980.
Ver mais
Dias M.C., Oliveira H., Costa A., Santos C. (2014) Improving elms performance under drought stress: The pretreatment with abscisic acid.
Environmental And Experimental Botany, 100
64-73.
Ver mais
Dias M.C., Correia C., Moutinho-Pereira J., Oliveira H., Santos C. (2014) Study of the effects of foliar application of ABA during acclimatization.
Plant Cell Tissue And Organ Culture, 117
, (2), 213-224. 1573-5044.
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Ferreira de Oliveira J.M.P., Remédios C., Oliveira H., Pinto P., Pinho F., Pinho S., Costa M., Santos C. (2014) Sulforaphane Induces DNA Damage and Mitotic Abnormalities in Human Osteosarcoma MG-63 Cells: Correlation with Cell Cycle and Apoptosis.
Nutrition And Cancer-an International Journal, 66
, (2), 325-334.
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Ascenso A., Ribeiro H., Marques H.C., Oliveira H., Santos C., Simoes S. (2014) Is Tretinoin Still a Key Agent for Photoaging Management?.
MINI-REVIEWS IN MEDICINAL CHEMISTRY, 14
, (8), 629-641.
Ver mais
Ascenso A., Ribeiro H., Marques H.C., Oliveira H., Santos C., Simoes S. (2014) Chemoprevention of photocarcinogenesis by lycopene.
EXPERIMENTAL DERMATOLOGY, 23
, (12), 874-878.
Ver mais
Ascenso A., Salgado A., Euleterio C., Praca F.G., Bentley M.V.L.B., Marques H.C., Oliveira H., Santos C., Simoes S. (2014) In vitro and in vivo topical delivery studies of tretinoin-loaded ultradeformable vesicles.
EUROPEAN JOURNAL OF PHARMACEUTICS AND BIOPHARMACEUTICS, 88
, (1), 48-55.
Ver mais
Oliveira H., Monteiro C., Pinho F., Pinho S., de Oliveira J.M.P.F., Santos C. (2014) Cadmium-induced genotoxicity in human osteoblast-like cells.
MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS, 775
38-47.
Ver mais
Coutinho L., de Oliveira J.M.P.F., Oliveira H., Santos C. (2014) Cytotoxic and genotoxic activity of hesperetin in an osteosarcoma in vitro model.
TOXICOLOGY LETTERS, 229
S157-S157.
Ver mais
de Oliveira J.M.P.F., Oliveira H., Pinho S., Pimentel F., Almeida L., Van Zoelen E.J.J., Santos C. (2014) Cytotoxic and genotoxic activity of fisetin (3, 3 ', 4 ', 7-tetrahydroxyflavone) in an osteosarcoma in vitro model.
PLANTA MEDICA, 80
, (16), 1412-1412.
Ver mais
Oliveira H., Costa A., Santos C. (2013) NaCl and Phaeomoniella chlamydospora affect differently starch and sucrose metabolism in grapevines.
Acta Scientiarum-Agronomy, 35
, (2), 153-159.
Ver mais
Nora S., Castro S., Loureiro J., Gonçalves A.C., Oliveira H., Castro M., Santos C. , Silveira P. (2013) Flow cytometric and karyological analyses of Calendula species from Iberian Peninsula.
Plant Systematics And Evolution, 299
, (5), 853-864.
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Ascenso A., Pinho S., Eleutério C., Praça F., Oliveira H., Bentley M.V., Santos C., Silva O., Simões S. (2013) Lycopene from Tomatoes:Vesicular Nanocarrier Formulations for Dermal Delivery.
Journal Of Agricultural And Food Chemistry, 61
, (30), 7284-7293.
Ver mais
Matos R.C., Bessa M., Oliveira H., Gonçalves F., Pereira M.L., Nunes B. (2013) Mechanisms of kidney toxicity for chromium- and arsenic-based preservatives: Potential involvement of a pro-oxidative pathway.
Environmental Toxicology And Pharmacology, 36
, (3), 929-936.
Ver mais
Ferreira M., Matos R.C., Oliveira H., Nunes B., Pereira M.L. (2012) Impairment of mice spermatogenesis by sodium arsenite.
Human & Experimental Toxicology, 31
, (3), 290-302.
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Oliveira H., Sousa A., Alves A., Nogueira A.J.A., Santos C. (2012) Inoculation with Ophiostoma novo-ulmi subsp. americana affects photosynthesis, nutrition and oxidative stress in in vitro Ulmus minor plants.
Environmental And Experimental Botany, 77
146-155.
Ver mais
Guimarães G., Cardoso L., Oliveira H., Santos C., Duarte P., Sottomayor M. (2012) Cytogenetic characterization and genome size of the medicinal plant Catharanthus roseus (L.) G. Don.
AoB Plants,
.
Ver mais
Oliveira H., Lopes T., Almeida T., Pereira M.L., Santos C. (2012) Cadmium-induced genetic instability in mice testis.
Human & Experimental Toxicology, 31
, (12), 1228-1236.
Ver mais
Monteiro C., Santos C., Pinho S., Oliveira H., Pedrosa T., Dias M.C. (2012) Cadmium-induced cyto- and genotoxicity are organ-dependent in lettuce.
Chemical Research In Toxicology, 25
, (7), 1423-1434.
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Oliveira H., Santos C. (2011) AN INTEGRATIVE VIEW OF SODIUM CHLORIDE STRESS AND PHAEOMONIELLA SP. INOCULATION ON GROWTH AND NUTRIENT ACCUMULATION AND PATTERNING IN IN VITRO GRAPEVINE PLANTS.
Journal Of Plant Nutrition, 34
, (4), 557-572.
Ver mais
Oliveira H., Guevara M., Santos T., Santos C., Pereira M.L. (2010) Evaluation of in vivo reproductive toxicity of potassium chromate in male mice.
Experimental And Toxicologic Pathology, 62
391-404.
Ver mais
Oliveira H, Barros A, delgadillo I, , Coimbra M, , Santos C (2009) Effects of fungi inoculation and salt stress on physiology and biochemistry of in vitro grapevines: emphasis on sugar composition changes by FT-IR analyses.
Environmental And Experimental Botany, 65
, (1), 1-10.
Ver mais
Oliveira H., spano M., Santos C., Pereira M.L. (2009) Adverse effects of cadmium exposure on mouse sperm.
Reproductive Toxicology, 28
, (4), 550-559.
Ver mais
Oliveira H, Spanò M, Santos C, Pereira ML (2009) Lead chloride affects sperm motility and acrosome reaction in mice.
Cell Biology And Toxicology , 25
341-353.
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Santos C., Fragoeiro S., Oliveira H., Phillips A. (2006) Response of Vitis vinifera L. plants inoculated with Phaeoacremonium angustius and Phaeomoniella chamydospora to thiabendazole, resveratrol and sodium arsenite.
Scientia Horticulturae, 107
131-136.
Ver mais
Oliveira H., Santos T.M., Ramalho-Santos J., Pereira M.L. (2006) Histopathological effects of Hexavalent Chromium in Mice Kidney.
Bulletin Of Environmental Contamination And Toxicology, 76
977-983.
Ver mais
Oliveira H., Loureiro J., Filipe L., Santos C., Ramalho-Santos J., Sousa M., Pereira M.L. (2006) Flow cytometry evaluation of lead and cadmium effects on mouse spermatogenesis.
Reproductive Toxicology, 22
529-535.
Ver mais
Pereira ML, Pires das Neves R., Oliveira H., Santos T.M., Pedrosa de Jesus J. (2005) Effect of Cr(V) on reproductive organ morphology and sperm parameters: An experimental study in mice.
Environmental Health: A Global Access Science Source , 4
9.
Ver mais
Guevara M.A., Silva A., Oliveira H., Pereira M.D., Morgado F. (2003) Segmentation and morphometry of histological sections using deformable models: A new tool for evaluating testicular histopathology.
PROGRESS IN PATTERN RECOGNITION, SPEECH AND IMAGE ANALYSIS, 2905
282-290. 3-540-20590-X.
Ver mais
Santos C, Falcão IP, Pinto G, Oliveira H, Loureiro J (2002) Nutrient responses and glutamate and proline metabolism in sunflower plants and calli under Na2SO4 stress.
Journal Of Plant Nutrition And Soil Science, 165
326-372.
Ver mais
Debasu, M.L., Oliveira, H., Rocha, J., Carlos, L.D. Colloidal (Gd0.98Nd0.02)2O3 nanothermometers operating in a cell culture medium within the first and second biological windows .
Journal Of Rare Earths, 38
, (5), 483-491.
Ver mais
Helena Cristina Correia de Oliveira
Investigadora Auxiliar- CEEC FCT
- Researcher ID: M-5068-2013
- ORCID: https://orcid.org/0000-0002-4673-0696
- Ciencia ID: 3D17-FE83-8860
- Departamento: Departamento de Biologia
- Grupo de Investigação: Aquatic Toxicology & Risk Assessment (ATRA)
- ISI Web of KnowledgeSM search factor: Author=(Oliveira H OR Oliveira Helena) AND Address=(Aveiro)
Interesses de investigação
Lanthanide-dopped upconverting nanoparticles for biological applications
Development of nanoparticles for photothermal therapy
Inhalation toxicity of carbon-based nanomaterials
Toxicity of metals and metal nanoparticles in in vitro models
Evaluation of the antitumor potential of phytocompounds
Application of flow cytometry to assess functional parameters in plant and animal cells
Development of nanoparticles for photothermal therapy
Inhalation toxicity of carbon-based nanomaterials
Toxicity of metals and metal nanoparticles in in vitro models
Evaluation of the antitumor potential of phytocompounds
Application of flow cytometry to assess functional parameters in plant and animal cells
Graus académicos
2009- PhD in Biology, University of Aveiro, Portugal
2002- M.Sc. in Coastal Zones Sciences, University of Aveiro, Portugal
1998- Degree in Biology, University of Aveiro, Portugal
2002- M.Sc. in Coastal Zones Sciences, University of Aveiro, Portugal
1998- Degree in Biology, University of Aveiro, Portugal
Atividades científicas
01/04/2019-present-Assistant Researcher (CEECIND/04050/2017 - CEEC Individual 2017), Department of Biology & CESAM, University of Aveiro
01/01/2019-31/03/2019-Researcher (NT-DL57), Department of Biology & CESAM, University of Aveiro
2016-2019 Post-doctoral researcher financed by FCT under the theme “Evaluation of the pulmonary toxicity potential of graphene nanomaterials: cytotoxicity, genotoxicity and metabolic profiling”.
2013-2016- Post-doctoral researcher financed by FCT under the theme “Cytotoxicity and genotoxicity of legacy metal contaminants and by metal derived emerging contaminants: focus on the metal-based nanoparticles”.
2009-2013- Post-doctoral researcher financed by FCT under the theme “Programmed cell death and cell cycle regulation under cadmium stress in plant and animal models”
01/01/2019-31/03/2019-Researcher (NT-DL57), Department of Biology & CESAM, University of Aveiro
2016-2019 Post-doctoral researcher financed by FCT under the theme “Evaluation of the pulmonary toxicity potential of graphene nanomaterials: cytotoxicity, genotoxicity and metabolic profiling”.
2013-2016- Post-doctoral researcher financed by FCT under the theme “Cytotoxicity and genotoxicity of legacy metal contaminants and by metal derived emerging contaminants: focus on the metal-based nanoparticles”.
2009-2013- Post-doctoral researcher financed by FCT under the theme “Programmed cell death and cell cycle regulation under cadmium stress in plant and animal models”
Publicações
Artigos WoS
(86)
Outros artigos
(7)
Livros
(0)
Capítulo de Livro
(4)
Teses
(7)
Comunicações
(46)
Outras Publicações
(0)
Relatórios
(0)
Projetos
HOTsPOT: Novas nanopartículas de conversão ascendente para terapia multimodal do melanoma - terapia fototérmica, terapia fotodinâmica e quimioterapia
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REFINECYANO - Valorização de pigmentos de cianobactérias pela aplicação do conceito de biorefinaria
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SOPRO - Perfis químicos e toxicológicos de fontes de matéria particulada em atmosfera urbana
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Desenvolvimento de nanoplataformas eficientes de aquecimento e monitorização para imagem intracelular e hipertermia local
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Nanobioinks - Engenharia de nanofibras de origem biológica para o desenvolvimento de biotintas nanoestruturadas de elevada performance para bio-impressão 3-D
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GOGOFROG: Métodos alternativos a experimentação animal para análise de risco em anfíbios: linhas celulares e espermatozóides
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NanoReproTox - Desvendando os impactos ecológicos da toxicidade de nanopartículas na reprodução de organismos marinhos
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nanoHYperTHerm - Nanopartículas integrando aquecedores e termómetros: aplicações ao movimento Browniano e em hipertermia
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PLATOX-Investigações in vitro e in vivo para obtenção de dados validados de toxicidade de nanoplaquetas de grafeno vs. referencia de carbono
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Análise de perfis metabólicos: uma nova metodologia para avaliação dos efeitos toxicológicos e biológicos de nanomateriais
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ASSAY - Avaliação do deStino e efeitoS de nanopartículas de prata em ecossistemas Aquáticos
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BIO.REM - Integração de múltiplos BIOmarcadores de toxicidade num ensaio de fitoREMediação de locais contaminados com Pb e Cd
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Orientações científicas
PhD (Orientador Principal):
Daniela Filipa Rodrigues Figueiredo
(CESAM member)
PhD (Orientador Principal):
Párástu Mariana Baghaei Oskoei
(CESAM member)
PhD (Co-orientador):
João Pedro Fernandes Carvalho
(not a CESAM member)
PhD (Co-orientador):
Tatiana Deolinda dos Santos Teixeira da Silva
(not a CESAM member)
PhD (Co-orientador):
Nicole Silva Lameirinhas
(not a CESAM member)
Master (Orientador Principal):
Maryam Nasirpour
(not a CESAM member)
Master (Orientador Principal):
Rúben Afonso
(not a CESAM member)
Master (Orientador Principal):
David Brandão
(not a CESAM member)
Master (Orientador Principal):
Débora Reis
(not a CESAM member)
Master (Orientador Principal):
Juliane Viegas
(not a CESAM member)
Master (Orientador Principal):
João Emanuel Barbosa
(not a CESAM member)
Master (Orientador Principal):
Bruna Teixeira
(not a CESAM member)
Master (Orientador Principal):
Carolina Roxo
(not a CESAM member)
Master (Orientador Principal):
Sandra Cristina Pinto Martins
(not a CESAM member)
Master (Orientador Principal):
Francisco Carvalho Vieira Pinho
(not a CESAM member)
Master (Orientador Principal):
Tiago José de Assunção Carvalho e Pedrosa Pinto
(not a CESAM member)
Master (Orientador Principal):
Pedro Miguel da Costa Amaral Pinto
(not a CESAM member)
Master (Orientador Principal):
Fernanda Oliveira Esteves Rosário
(ex-CESAM member)
Master (Orientador Principal):
Catarina Fortuna dos Remédios
(ex-CESAM member)
Master (Orientador Principal):
Maria Eugénia Marques da Costa
(ex-CESAM member)
Master (Co-orientador):
Ana Catarina Menezes
(not a CESAM member)
Master (Co-orientador):
Ana Catarina Menezes
(not a CESAM member)
Master (Co-orientador):
Corine Reis
(not a CESAM member)
Master (Co-orientador):
Verónica Isabel Correia Bastos
(not a CESAM member)
Master (Co-orientador):
Juliana Sousa
(not a CESAM member)
Master (Co-orientador):
Marta Isabel Esteves Pinheiro
(not a CESAM member)
Master (Co-orientador):
Juliana Moreira Crespo
(not a CESAM member)
bolseiro investigação (Orientador Principal):
Catarina Menezes
(not a CESAM member)
Pesquisa (Orientador Principal):
Fábio Campos
(not a CESAM member)
Pesquisa (Orientador Principal):
Ruben Afonso
(not a CESAM member)
Pesquisa (Orientador Principal):
Carolina Mota
(not a CESAM member)
Pesquisa (Orientador Principal):
Ânia Micaelo
(not a CESAM member)
Bolseiro de Investigação (Orientador Principal):
Marta Filipa Godinho Maia
(ex-CESAM member)
Bolseiro de Investigação (Mestre) (Orientador Principal):
Párástu Mariana Baghaei Oskoei
(CESAM member)
Research fellow (Master) (Orientador Principal):
Ana Isabel da Silva Mendes
(not a CESAM member)
Research fellow (Master) (Orientador Principal):
Ana Catarina Menezes
(not a CESAM member)
Pesquisa (Orientador Principal):
Diana Roberta da Cruz Ribeiro
(not a CESAM member)
Pesquisa (Orientador Principal):
Catarina Remédios
(not a CESAM member)
Projeto (Orientador Principal):
Mariana Mendes Pinto
(not a CESAM member)
Short term scientific mission (Orientador Principal):
Cynthia Kembuan
(not a CESAM member)
Short term scientific mission (Orientador Principal):
Anna Ekner-Grzyb
(not a CESAM member)
Projeto (Co-orientador):
Daniel Carvalho
(not a CESAM member)
PhD (Orientador Principal):
Daniela Filipa Rodrigues Figueiredo
(CESAM member)
PhD (Co-orientador):
Verónica Isabel Correia Bastos
(CESAM member)
PhD (Co-orientador):
Joana Carolina Quintela Carrola
(not a CESAM member)
PhD (Co-orientador):
Fernanda Oliveira Esteves Rosário
(ex-CESAM member)
PhD (Co-orientador):
Maria Cristina Monteiro
(ex-CESAM member)
Destaques
Invited to co-editor of the special issue “Legacy and emerging contaminants in plants: From the Gene to the Field” to the Journal of Botany
Arbitragem em Revistas Científicas Internacionais
- Reproductive Toxicology
- Journal of the Serbian Chemical Society
- Environmental and Experimental Botany
- Human and Experimental Toxicology
- Australasian Journal of Plant Pathology
- Urology Journal
- Ecotoxicology and Environmental Safety
- British Journal of Pharmaceutical Research
- Plant Physiology and Biochemistry
- Turkish Journal of Biology
- Environmental Chemistry Letters
- British Journal of Medicine and Medical Research
- Life Sciences
- Particle and Fibre Toxicology
- Nanotoxicology
- Toxicology in Vitro
- Beilstein Journal of Nanotechnology
- Ecological Indicators
- Drug and Chemical Toxicology
Orientação/co-orientação de alunos de pós graduação
PhD:
Fernanda Rosário. Thesis: “Unraveling pathways of cyto and genotoxicity of AgNP in lung and keratinocyte cells: an in vitro approach”. PhD in Biology. University of Aveiro. Concluded in 2018.
Joana Carolina Quintela Carrola. Thesis: “Evaluation of the biological effects and toxicity mechanisms of silver nanoparticles through metabolic profiling of human cells”. PhD in Nanosciences and nanotechnology. University of Aveiro. Concluded in 2017
Verónica Bastos. Thesis: “Do metal-based nanomaterials induce cytotoxicity and genotoxicity in human intestinal cells?”. PhD in Biology. University of Aveiro. Concluded in 2016.
Maria Cristina Monteiro. Thesis: "Cytogenicity of chromium and cadmium in plants and in human cells". PhD in Biology. University of Aveiro. Concluded in 2016
MASTER:
Telma Veloso. Thesis: “Evaluation of the bioactivity of bacterial extracts from bacterial isolates from caves”. MSC in Toxicology and Ecotoxicology. University of Aveiro. Concluded in 2018
Parastu Oskoei. Thesis: “Unravelling genotoxic effects of pesticides - in vitro and ex vivo assays as screening tools”. MSC in Toxicology and Ecotoxicology. University of Aveiro. Concluded in 2018
Bruna Teixeira Thesis: “Evaluation of the genotoxic potential of graphene nanomaterials”. MsC in Molecular and Cellular Biology. University of Aveiro. Concluded in 2018
Carolina Roxo. Thesis: “Evaluation of the cytotoxic potential of graphene nanomaterials”. MsC in Molecular and Cellular Biology. University of Aveiro. Concluded in 2017.
Martha Raquel Pereira Santos. Thesis: “Comunidade Bacteriana como Ferramenta Complementar à Diretiva Quadro da Água na Avaliação da Qualidade Ecológica do Rio Caima. MsC in Microbiology. University of Aveiro. Concluded in 2017
Débora Reis “Characterization of the cytotoxic potential of graphene nanoplatelets in lung cells” MsC in Molecular and Cellular Biology. Department of Biology, University of Aveiro. Concluded in 2016
Juliane Sousa. “Cytotoxic Potential of Graphene Oxide in Human Lung Adenocarcinoma Cell Line” MsC in Molecular and Cellular Biology. Department of Biology, University of Aveiro. Concluded in 2016
Maryam Nasirpour. Thesis: “Silver nanoparticles synthesized using plant extracts: toxicity screening and metabolic profiling in human cells”. FAME Master Student. Universidade de Aveiro. Concluída em 2015
Ana Catarina Menezes. Thesis: “Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors” Mestrado em Ciências Biofarmacêuticas. Universidade de Lisboa. Concluída em 2015
Sandra Cristina Pinto Martins. Thesis “Assessment of circulating endothelial progenitor cells by flow cytometry” MsC in Molecular and Cellular Biology. Departamento de Biologia, Universidade de Aveiro. Concluída em 2015
Corine Santos Reis. Thesis: “Genotoxic effects of silver nanoparticles on lung cells” MsC in Applied Biology. Departamento de Biologia, Universidade de Aveiro. Concluída em 2013.
Fernanda Rosário. Thesis: “Effects of Silver Nanoparticles on osteosarcoma and lung cell lines”. Mestrado em Biologia Aplicada. Departamento de Biologia, Universidade de Aveiro. Concluída em 2012.
Catarina Remédios. Thesis: “Cytotoxic effect of sulforaphane in Human osteosarcoma cells”. Mestrado em Biologia Aplicada. Departamento de Biologia, Universidade de Aveiro. Concluída em 2012.
Maria Eugénia Costa. Thesis: “Oxidative Stress Induction by Sulforaphane on human Osteosarcoma”. Mestrado em Biologia Aplicada. Departamento de Biologia, Universidade de Aveiro. Concluída em 2012.
Marta Isabel Esteves Pinheiro. Thesis: “Alterações no metaboloma de queratinócitos por exposição ao carragenano como veículo de entrega de fármacos”. Mestrado em Bioquímica. Departamento de Química, Universidade de Aveiro. Concluída em 2012
Juliana Sousa. “Análise de osteoblastos in vitro por microscopia”. Mestrado em Biologia Molecular e Celular. Departamento de Biologia, Universidade de Aveiro. Concluída em 2012.
Verónica Bastos. Tese:" Efeitos genotóxicos de contaminantes ambientais em cães". Mestrado em Biologia Aplicada ramo de Toxicologia e Ecotoxicologia Departamento de Biologia, Universidade de Aveiro. Concluida em 2011.
Pedro Amaral. Tese:" Evaluation of DNA damage induced by sulforaphane on MG-63 cells". Mestrado em Biologia Aplicada - Ramo de Biologia Molecular, Departamento de Biologia, Universidade de Aveiro. Concluida em 2011.
Tiago Pinto. Tese:" Studies on cadmium induced toxicity in human osteoblasts: apoptosis and oxidative stress". Mestrado em Biologia Aplicada - Ramo de Biologia Molecular, Departamento de Biologia, Universidade de Aveiro. Concluida em 2011.
Francisco Pinho. Tese: "Evaluation of the cytotoxic effects of cadmium in human osteobolasts". Mestrado em Biologia Aplicada - Ramo de Biologia Molecular, Departamento de Biologia, Universidade de Aveiro. Concluida em 2011.
Participação em projectos de investigação
"PLATOX:In vitro and in vivo investigations to generate validated toxicity data of graphene nanoplatelets vs. a carbon black reference" (2015-2017). ERASIINN/0003/2013
"Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials" (2012-2015). PTDC/SAU-TOX/120953/2010
"BIO.REM: Integrating multiple toxicological BIOmarkers in a phytoREMemediation assay of Pb and Cd contaminated sites" (2011-2014). PTDC/AAC-MB/112804/2009
"ASSAY - Assessment of fate and effects of Silver nanoparticleS in Aquatic ecosystems" (2011-2014)PTDC/AAC-AMB/113649/2009
"Técnicas de diagnóstico tradicionais e inovadoras na biomonitorização da fertilidadade masculina". UA- Projecto I&DT, Ciências e Tecnologias da Saúde/22. Concluido em 2005.
"Estudo bioquímico e ultraestrutural de videiras com o síndroma da esca e caracterização de fungos responsáveis pela doença". MCT-PraxisXXI-POCTI/AGR/C/11142. Concluido em 2002.
Acções COST
Membro do comité de gestão:
CM1403: The European upconversion network - from the design of photon-upconverting nanomaterials to biomedical applications- as Management Committee Member. Líder do grupo de trabalho 5-Toxicologia http://www.ucnp.eu/
CA17140: Cancer nanomedicine - from the bench to the bedside- as Management Committee substitute
CA17104: New diagnostic and therapeutic tools against multidrug resistant tumors- as Management Committee substitute
CA15107: Multi-Functional Nano-Carbon Composite Materials Network (MultiComp). http://www.cost.eu/COST_Action.....
TD1204: Modelling Nanomaterial Toxicity (MODENA) http://www.cost.eu/COST_Action.....
Teses
H. Oliveira (2009) Avaliação do efeito de metais pesados na fertilidade do ratinho. Tese de doutoramento.
H. Oliveira (2002) Estudo bioquímico de videiras (Vitis vinifera L.) cultivadas in vitro em ambiente salino e infectadas com Phaeomoniella chlamydospora. Tese de mestrado
Financiamento do CESAM:
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