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Helena Cristina Correia de Oliveira

Helena Cristina Correia de Oliveira

Post-Doctoral Research Fellow

  • Department: Department of Biology
  • Research Group: Ecotoxicology
  • ISI Web of KnowledgeSM search factor : ResearcherID: M-5068-2013
  • Title: Evaluation of the pulmonary toxicity potential of graphene nanomaterials: cytotoxicity, genotoxicity and metabolic profiling Supervisor: Mário Guilherme Garcês Pacheco Category: BO Grant type: BPD Funding entity: FCT Grant reference: SFRH/BPD/111736/2015 Start date: 2016-03-01 End date: 2019-02-28


Highlight

Invited to co-editor of the special issue “Legacy and emerging contaminants in plants: From the Gene to the Field” to the Journal of Botany

Peer review of international scientific journals


  • Reproductive Toxicology

  • Journal of the Serbian Chemical Society

  • Environmental and Experimental Botany

  • Human and Experimental Toxicology

  • Australasian Journal of Plant Pathology

  • Urology Journal

  • Ecotoxicology and Environmental Safety

  • British Journal of Pharmaceutical Research

  • Plant Physiology and Biochemistry

  • Turkish Journal of Biology

  • Environmental Chemistry Letters

  • British Journal of Medicine and Medical Research

  • Life Sciences

  • Particle and Fibre Toxicology

  • Nanotoxicology

  • Toxicology in Vitro

  • Beilstein Journal of Nanotechnology

  • Ecological Indicators

  • Drug and Chemical Toxicology

Supervision/co-supervision of post-graduation students

PhD:


Joana Carolina Quintela Carrola. Thesis: “Evaluation of the biological effects and toxicity mechanisms of silver nanoparticles through metabolic profiling of human cells”. PhD in Nanosciences and nanotechnology. University of Aveiro.Concluded in 2017


Verónica Bastos. Thesis: “Do metal-based nanomaterials induce cytotoxicity and genotoxicity in human intestinal cells?”. PhD in Biology. University of Aveiro. Concluded in 2016.


Maria Cristina Monteiro. Thesis: "Cytogenicity of chromium and cadmium in plants and in human cells". PhD in Biology. University of Aveiro. Concluded in 2016


MASTER:


Débora Reis “Characterization of the cytotoxic potential of graphene nanoplatelets in lung cells” MsC in Molecular and Cellular Biology. Department of Biology, University of Aveiro. Concluded in 2016


Juliane Sousa. “Cytotoxic Potential of Graphene Oxide in Human Lung Adenocarcinoma Cell Line” MsC in Molecular and Cellular Biology. Department of Biology, University of Aveiro. Concluded in 2016


Maryam Nasirpour. Thesis: “Silver nanoparticles synthesized using plant extracts: toxicity screening and metabolic profiling in human cells”. FAME Master Student. University of Aveiro. Concluded in 2015.


Ana Catarina Menezes. Thesis: “Prevention of Photocarcinogenesis by Agonists of 5-HT1A and Antagonists of 5-HT2A Receptors” MsC in Biopharmaceutical Sciences, University of Lisboa. Concluded in 2015.


Sandra Cristina Pinto Martins. Thesis “Assessment of circulating endothelial progenitor cells by flow cytometry” MsC in Molecular and Cellular Biology. Departament of Biology, Universidade de Aveiro. Concluded in 2015.


Corine Santos Reis. Thesis: “Genotoxic effects of silver nanoparticles on lung cells” MsC in Applied Biology. Department of Biology, University of Aveiro. Concluded in 2013.


Fernanda Rosário. Thesis: “Effects of Silver Nanoparticles on osteosarcoma and lung cell lines”. MsC in Applied Biology. Department of Biology, University of Aveiro. Concluded  in 2012.


Catarina Remédios. Thesis: “Cytotoxic effect of sulforaphane in Human osteosarcoma cells”. MsC in Applied Biology. Department of Biology, University of Aveiro. Concluded  in 2012.


Maria Eugénia Costa. Thesis: “Oxidative Stress Induction by Sulforaphane on human Osteosarcoma”. MsC in Applied Biology. Department of Biology, University of Aveiro.  Concluded  in 2012.


Marta Isabel Esteves Pinheiro. Thesis: “Alterações no metaboloma de queratinócitos por exposição ao carragenano como veículo de entrega de fármacos”. MsC in Biochemistry. Department of Chemistry, University of Aveiro. Concluded in 2012


Juliana Sousa. Análise de osteoblastos in vitro por microscopia.  MsC in Molecular and Cellular Biology. Department of Biology, University of Aveiro. Concluded  in 2012.


Verónica Bastos. Thesis:" Genotoxic effects of environmental contaminants in dogs." MSc in Biologia Aplicada ramo de Toxicologia e Ecotoxicologia Departamento de Biologia, Universidade de Aveiro. Concluded in 2011.


Pedro Amaral. Thesis:" Evaluation of DNA damage induced by sulforaphane on MG-63 cells". MSc in Biologia Aplicada - Ramo de Biologia Molecular, Departamento de Biologia, Universidade de Aveiro. Concluded in 2011.


Tiago Pinto. Thesis:"Studies on cadmium induced toxicity in human osteoblasts: apoptosis and oxidative stress". MSc in Biologia Aplicada - Ramo de Biologia Molecular, Departamento de Biologia, Universidade de Aveiro. Concluded in 2011.


Francisco Pinho. Thesis:" Evaluation of the cytotoxic effects of cadmium in human osteobolasts". MSc in Biologia Aplicada - Ramo de Biologia Molecular, Departamento de Biologia, Universidade de Aveiro. Concluded in 2011.

Participation in research projects

"PLATOX:In vitro and in vivo investigations to generate validated toxicity data of graphene nanoplatelets vs. a carbon black reference" (2015-2017). ERA­SIINN/0003/2013


"Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials" (2012-2015). PTDC/SAU-TOX/120953/2010


"BIO.REM: Integrating multiple toxicological BIOmarkers in a phytoREMemediation assay of Pb and Cd contaminated sites" (2011-2014). PTDC/AAC-MB/112804/2009


"ASSAY - Assessment of fate and effects of Silver nanoparticleS in Aquatic ecosystems" (2011-2014)PTDC/AAC-AMB/113649/2009


  "Técnicas de diagnóstico tradicionais e inovadoras na biomonitorização da fertilidadade masculina". UA- Projecto I&DT, Ciências e Tecnologias da Saúde/22. Concluded in 2005


 "Estudo bioquímico e ultraestrutural de videiras com o síndroma da esca e caracterização de fungos responsáveis pela doença". MCT-PraxisXXI-POCTI/AGR/C/11142. Concluded in 2002

COST Actions

Member of the management committee:


CM1403: The European upconversion network - from the design of photon-upconverting nanomaterials to biomedical applications- as Management Committee Member. Leader of the Working Group 5-Toxicology http://www.ucnp.eu/


CA15107: Multi-Functional Nano-Carbon Composite Materials Network (MultiComp). http://www.cost.eu/COST_Action.....


TD1204: Modelling Nanomaterial Toxicity (MODENA) http://www.cost.eu/COST_Action.....

Theses

H. Oliveira (2009) Avaliação do efeito de metais pesados na fertilidade do ratinho. PhD thesis.


H. Oliveira (2002) Estudo bioquímico de videiras (Vitis vinifera L.) cultivadas in vitro em ambiente salino e infectadas com Phaeomoniella chlamydospora. M.Sc. thesis

Research interests

Toxicity of metals and metal nanoparticles in in vitro models


Evaluation of the effects of phytocompounds on tumoral cells


Application of flow cytometry to assess functional parameters in plant and animal cells

Academic qualifications

 2009- PhD in Biology, University of Aveiro, Portugal


2002- M.Sc. in Coastal Zones Sciences, University of Aveiro, Portugal


1998- Degree in Biology, University of Aveiro, Portugal

Current activity

Post-doctoral researcher financed by FCT (grant reference: SFRH/BPD/111736/2015). 

Scientific Supervision

In progress (0)
Concluded (36)
Master (Main Supervisor): Maryam Nasirpour (not a CESAM member)

Master (Main Supervisor): Débora Reis (not a CESAM member)

Master (Main Supervisor): Juliane Viegas (not a CESAM member)

Master (Main Supervisor): Bruna Teixeira (not a CESAM member)

Master (Main Supervisor): Carolina Roxo (not a CESAM member)

Master (Main Supervisor): Sandra Cristina Pinto Martins (not a CESAM member)

Master (Main Supervisor): Francisco Carvalho Vieira Pinho (not a CESAM member)

Master (Main Supervisor): Tiago José de Assunção Carvalho e Pedrosa Pinto (not a CESAM member)

Master (Main Supervisor): Pedro Miguel da Costa Amaral Pinto (not a CESAM member)

Master (Main Supervisor): Fernanda Oliveira Esteves Rosário (ex-CESAM member)

Master (Main Supervisor): Catarina Fortuna dos Remédios (ex-CESAM member)

Master (Main Supervisor): Maria Eugénia Marques da Costa (ex-CESAM member)

Master (Co-supervisor): Ana Catarina Menezes (not a CESAM member)

Master (Co-supervisor): Ana Catarina Menezes (not a CESAM member)

Master (Co-supervisor): Corine Reis (not a CESAM member)

Master (Co-supervisor): Verónica Isabel Correia Bastos (not a CESAM member)

Master (Co-supervisor): Juliana Sousa (not a CESAM member)

Master (Co-supervisor): Marta Isabel Esteves Pinheiro (not a CESAM member)

Master (Co-supervisor): Juliana Moreira Crespo (not a CESAM member)

bolseiro investigação (Main Supervisor): Catarina Menezes (not a CESAM member)

Pesquisa (Main Supervisor): Fábio Campos (not a CESAM member)

Pesquisa (Main Supervisor): Ruben Afonso (not a CESAM member)

Pesquisa (Main Supervisor): Carolina Mota (not a CESAM member)

Pesquisa (Main Supervisor): Ânia Micaelo (not a CESAM member)

Research fellow (Master) (Main Supervisor): Ana Isabel da Silva Mendes (not a CESAM member)

Research fellow (Master) (Main Supervisor): Ana Catarina Menezes (not a CESAM member)

Pesquisa (Main Supervisor): Diana Roberta da Cruz Ribeiro (not a CESAM member)

Pesquisa (Main Supervisor): Catarina Remédios (not a CESAM member)

Projeto (Main Supervisor): Mariana Mendes Pinto (not a CESAM member)

Short term scientific mission (Main Supervisor): Cynthia Kembuan (not a CESAM member)

Short term scientific mission (Main Supervisor): Anna Ekner-Grzyb (not a CESAM member)

Projeto (Co-supervisor): Daniel Carvalho (not a CESAM member)

PhD (Co-supervisor): Verónica Isabel Correia Bastos (ex-CESAM member)

PhD (Co-supervisor): Joana Carolina Quintela Carrola (not a CESAM member)

PhD (Co-supervisor): Fernanda Oliveira Esteves Rosário (ex-CESAM member)

PhD (Co-supervisor): Maria Cristina Monteiro (ex-CESAM member)

Projects

In progress (6)
HOTsPOT - Novel upconversion nanoparticles for multimodal therapy of melanoma: pHOtothermal Therapy, PhOtodynamic therapy and chemoTherapy See more

REFINECYANO - Using biorefinery to value cyanobacteria pigments See more

SOPRO - Chemical and toxicological SOurce PROfiling of particulate matter in urban air See more

GOGOFROG: Alternative methods to animal experimentation for amphibian risk assessment: cell lines and spermatozoa See more

NanoReproTox-Unraveling the ecological impacts of nanoparticles toxicity in the reproduction of marine organisms See more

nanoHYperTHerm - Nanoheaters and nanothermometers playing together: towards applications in Brownian motion and hyperthermia See more

Concluded (4)
PLATOX-In vitro and in vivo investigations to generate validated toxicity data of graphene nanoplatelets vs. a carbon black reference See more

Metabolic profiling: a novel tool for evaluation of the toxicological and biological effects of nanomaterials See more

ASSAY: Assessment of fate and effects of Silver nanoparticleS in Aquatic ecosYstems See more

BioREM See more

Publications

WoS Papers (58)
Other Papers (8)
Books (0)
Book Chapter (4)
Thesis (5)
Communications (42)
Other Publications (0)

CESAM Funding: