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Maria do Rosário Domingues

Maria do Rosário Domingues

Associate Professor

  • Department: Chemistry
  • Research Group: Marine Biotechnology & Aquaculture


Short Curriculum Vitae

Rosário Domingues, Ph.D. is presently Associated Professor with Habilllitation in the Department of Chemistry & CESAM, University of Aveiro (UA), Aveiro, Portugal. She is Vice Head of the Department of Chemistry and Director of the Doctoral Program of Biochemistry at UA. She graduated in Pharmaceutical Sciences, University of Coimbra (1990), received her Ph.D. degree in Chemistry (1998), and Habilitation in Biochemistry (2014) at the University of Aveiro. Since 2016 she held the contract of Associated Professor with Habilitation in the Mass Spectrometry Centre, Department of Chemistry, University of Aveiro (UA). From 1991 to 1998 she was Assistant at UA, and Auxiliar Professor between 1998-2016. She has over 25 years of research experience in the field of mass spectrometry, and is a well-established researcher in the field of lipidomics, glycomics and changes in biomolecules associated with oxidative stress monitored by mass spectrometry. She is one of the co-leaders of the Lipidomics Laboratory of the Mass Spectrometry Centre of the UA. Her major research interests are focused in Lipidomics, namely: Marine Lipidomics, Oxidative Lipidomics and Lipidomics in Health and Disease. She is/has already been PI and /or team member of more than 20 projects funded by national and European programs. In the present, she is the coordinator at UA of two European projects, the project H2020-MSCA-ITN-2015 Innovative Training Networks (ITNH2020-MSCA-ITN-2015) “MASS spectrometry TRaining in Protein Lipoxidation ANalysis for Inflammation; MASSTRPLAN (Grant number 675132) and the project GENIALG - Genetic diversity exploitation for Innovative macro-algal biorefinery (ANR-15-MRSE-0015), Innovation actions BG-01-2016: Large-scale algae biomass integrated biorefineries. To date, she has authored one book, six book chapters and more than 220 articles published in international journals w

Area of scientific activity

Mass Spectrometry


Analysis of oxidized biomolecules by mass spectrometry


Lipidomics


Marine Lipidomics


Lipidomics in Health and disease

Scientific Supervision

In progress
Concluded

Projects

In progress
  • Omics4Algae - Lipidomic tools for chemical phenotyping, traceability and valorisation of seaweeds from aquaculture as a sustainable source of high added-value compounds See more
  • SUShI - SUStainable use of Insect protein in aquaculture feed See more
  • TraSeafood Tracing the Geographic Origin of Seafood as a Pathway Towards the Smart Valorization of Endogenous Marine Resources See more
  • ValorMar -Integral Valorization of Marine Resources: Potential, Technological Innovation and New Applications See more
  • SmartBioR - Smart Valorization of Biological Marine Resources. See more
Concluded

Publications

WoS Papers (210)
da Costa E., Melo T., Moreira A.S.P., Bernardo C., Helguero L., Ferreira I., Cruz M.T., Rego A.M., Domingues P., Calado R., Abreu M.H., Domingues M.R. (2017) Valorization of Lipids from Gracilaria sp through Lipidomics and Decoding of Antiproliferative and Anti-Inflammatory Activity. In: Marine Drugs. 15, 3,
Martins J.D., Maciel E.A., Silva A., Ferreira I., Ricardo F., Domingues P., Neves B.M., Domingues M.R.M., Cruz M.T. (2016) Phospholipidomic Profile Variation on THP-1 Cells Exposed to Skin or Respiratory Sensitizers and Respiratory Irriant. In: Journal Of Cellular Physiology. 231, 12, 2639-2651.
Rey F., Moreira A.S.P., Ricardo F., Coimbra M.A., Domingues M.R.M., Domingues P., Rosa R., Queiroga H., Calado R. (2016) Fatty Acids of Densely Packed Embryos of Carcinus maenas Reveal Homogeneous Maternal Provisioning and No Within-Brood Variation at Hatching. In: Biological Bulletin. 230, 2, 120-129.
Ricardo F., Pimentel T., Moreira A.S.P., Rey F., Coimbra M.A., Domingues M.R., Domingues P., Leal M.C., Calado R. (2015) Potential use of fatty acid profiles of the adductor muscle of cockles (Cerastoderma edule) for traceability of collection site. In: Scientific Reports. 5,
Alves E., Melo T., Rey F., Moreira A.S.F., Domingues P., Domingues M.R. (2016) Polar lipid profiling of olive oils as a useful tool in helping to decipher their unique fingerprint. In: Lwt-food Science And Technology. 74, 371-377.
Almeida A., Calisto V., Domingues M.R.M., Esteves V.I., Schneider R.J., Soares A.M.V.M., Figueira E., Freitas R. (2017) Comparison of the toxicological impacts of carbamazepine and a mixture of its photodegradation products in Scrobicularia plana. In: Journal Of Hazardous Materials. 323, 220-232.
Filipe O.M.S., Mota N., Santos S.A.O., Domingues M.R.M., Silvestre A.J.D., Neves M.G.P.M.S., Simoes M.M.Q., Santos E.B.H. (2017) Identification and characterization of photodegradation products of metoprolol in the presence of natural fulvic acid by HPLC-UV-MSn. In: Journal Of Hazardous Materials. 323, 250-263.
Couto D., Melo T., Maciel E., Campos A., Alves E., Guedes S., Domingues M.R.M., Domingues P. (2016) New Insights on Non-Enzymatic Oxidation of Ganglioside GM1 Using Mass Spectrometry. In: Journal Of The American Society For Mass Spectrometry. 27, 12, 1965-1978.
Maciel E., Leal M.C., Lillebo A.I., Domingues P., Domingues M.R., Calado R. (2016) Bioprospecting of Marine Macrophytes Using MS-Based Lipidomics as a New Approach. In: Marine Drugs. 14, 3,
Santos P.S.M., Domingues M.R.M., Duarte A.C. (2016) Fenton-like oxidation of small aromatic acids from biomass burning in atmospheric water and in the absence of light: Identification of intermediates and reaction pathways. In: Chemosphere. 154, 599-603.
Sousa B., Melo T., Campos A., Moreira A.S.P., Maciel E., Domingues P., Carvalho R.P., Rodrigues T.R., Girao H., Domingues M.R.M. (2016) Alteration in Phospholipidome Profile of Myoblast H9c2 Cell Line in a Model of Myocardium Starvation and Ischemia. In: Journal Of Cellular Physiology. 231, 10, 2266-2274.
da Costa E., Melo T., Moreira A.S.P., Alves E., Domingues P., Calado R., Abreu M.H., Domingues M.R. (2015) Decoding bioactive polar lipid profile of the macroalgae Codium tomentosum from a sustainable IMTA system using a lipidomic approach. In: Algal Research-biomass Biofuels And Bioproducts. 12, 388-397.
Rey F., Alves E., Melo T., Domingues P., Queiroga H., Rosa R., Domingues M.R.M., Calado R. (2015) Unravelling polar lipids dynamics during embryonic development of two sympatric brachyuran crabs (Carcinus maenas and Necora puber) using lipidomics. In: Scientific Reports. 5,
Filipe O.M.S., Santos S.A.O., Domingues M.R.M., Vidal M.M., Silvestre A.J.D., Santos E.B.H. (2014) Effect of copper ions on the degradation of thiram in aqueous solution: Identification of degradation products by HPLC-MS/MS. In: Journal Of Hazardous Materials. 279, 125-132.
Lopes D., Melo T., Santos N., Rosa L., Alves E., Gomes M.C., Cunha A., Neves M.G.P.M.S., Faustino M.A.F., Domingues M.R.M., Almeida A. (2014) Evaluation of the interplay among the charge of porphyrinic photosensitizers, lipid oxidation and photoinactivation efficiency in Escherichia coli. In: Journal Of Photochemistry And Photobiology B-biology. 141, 145-153.
Melo T., Santos N., Lopes D., Alves E., Maciel E., Faustino M.A.F., Tomé J.P.C., Neves M.G.P.M.S., Almeida A. , Domingues P. , Segundo M.A., Domingues M.R.M. (2013) Photosensitized oxidation of phosphatidylethanolamines monitored by electrospray tandem mass spectrometry. In: Journal Of Mass Spectrometry. 48, 12, 1357–1365
Alves E., Santos N., Melo T., Maciel E., Dória L., Faustino M.A.F., Tomé J.P.C., Neves M.G.P.M.S., Cavaleiro J.A.S., Cunha A., Helguero L., Domingues P., Almeida A., Domingues M.R.M. (2013) Photodynamic oxidation of Escherichia coli membrane phospholipids: new insights based on lipidomics. In: Rapid Communications In Mass Spectrometry. 27, 23, 2717-2728.
Alves E., Melo T., Simões C., Faustino M.A.F., Tomé J.P.C., Neves M.G.P.M.S., Cavaleiro J.A.S. , Cunha Â., Gomes N.C.M., Domingues P., Domingues M.R.M., Almeida A. (2013) Photodynamic oxidation of Staphylococcus warneri membrane phospholipids: new insights based on lipidomics. In: Rapid Communications In Mass Spectrometry. 27, 14, 1607-1618.
Filipe O.M.S, Santos S.A.O., Domingues M.R.M., Vidal M.M.B., Silvestre A.J.D., Neto C.P., Santos E.B.H. (2013) Photodegradation of the fungicide thiram in aqueous solutions. Kinetic studies and identification of the photodegradation products by HPLC-MS/MS. In: Chemosphere. 91, 7, 993-1001.
Santos A.L., Moreirinha C., Lopes D., Esteves A.C., Henriques I., Almeida A., Domingues M.R.M., Delgadillo I., Correia A., Cunha A. (2013) Effects of UV Radiation on the Lipids and Proteins of Bacteria Studied by Mid-Infrared Spectroscopy. In: Environmental Science & Technology. 47, 12, 6306-6315.
Calisto V., Domingues M.R.M., Erny G.L., Esteves V. I. (2011) Direct photodegradation of carbamazepine followed by micellar electrokinetic chromatography and mass spectrometry. In: Water Research. 45, 3, 1095-1104.
Calisto V., Domingues M.R.M., Esteves V.I. (2011) Photodegradation of psychiatric pharmaceuticals in aquatic environments - kinetics and photodegradation products. In: Water Research. 45, 18, 6097-6106.
Silva A.M., Borralho A.C., Pinho S.A., Domingues M.R., Domingues P. (2011) Cross-Oxidation of Angiotensin II by glycerophosphatidylcholine oxidation products. In: Rapid Communication Mass Spectrometry. 25, 10, 1413-21.
Fonseca F., Sarmento A. C., Henriques I,, Samyn B., van Beeumen J., Domingues P., Domingues M. R., Saavedra M. J., Correia A. (2007) Biochemical characterization of SFC-1, a class A carbapenem- hydrolyzing beta-lactamase. In: Antimicrobial Agents And Chemotherapy. 51, 4512-4514.
Rocha-Rodrigues S., Rodriguez A., Goncalves I.O., Moreira A., Maciel E., Santos S., Domingues M.R., Fruhbeck G., Ascensao A., Magalhaes J. (2017) Impact of physical exercise on visceral adipose tissue fatty acid profile and inflammation in response to a high-fat diet regimen. In: International Journal Of Biochemistry & Cell Biology. 87, 114-124.
Rey F., Domingues M.R.M., Domingues P., Rosa R., Orgaz M.D.M., Queiroga H., Calado R. (2017) Effect of Maternal Size, Reproductive Season and Interannual Variability in Offspring Provisioning of Carcinus maenas in a Coastal Lagoon. In: Estuaries And Coasts. 40, 6, 1732-1743.
Ricardo F., Maciel E., Domingues R., Calado R. (2017) Spatio-temporal variability in the fatty acid profile of the adductor muscle of the common cockle Cerastoderma edule and its relevance for tracing geographic origin. In: Food Control. 81, 173-180.
da Costa E.V., Moreira A.S.P., Nunes F.M., Coimbra M.A., Evtuguin D.V., Domingues M.R.M. (2012) Differentiation of isomeric pentose disaccharides by electrospray ionization tandem mass spectrometry and discriminant analysis. In: Rapid Communications In Mass Spectrometry. 26, 24, 2897-2904.
Moreira A.S.P., da Costa E.V., Evtuguin D.V., Coimbra M.A., Nunes F.M., Domingues M.R.M. (2014) Neutral and acidic products derived from hydroxyl radical-induced oxidation of arabinotriose assessed by electrospray ionisation mass spectrometry. In: Journal Of Mass Spectrometry. 49, 4, 280-290.
Campos A.M., Ricardo F., Alves E., Reis A., Couto D., Domingues P., Domingues M.R.M. (2016) Lipidomic investigation of eggs' yolk: Changes in lipid profile of eggs from different conditions. In: Food Research International. 89, 177-185.
Azenha C.S.R., Coimbra M.A., Moreira A.S.P., Domingues P., Domingues M.R.M. (2013) Differentiation of isomeric beta-(1-4) hexose disaccharides by positive electrospray tandem mass spectrometry. In: Journal Of Mass Spectrometry. 48, 5, 548-552.
Moreira A.S.P., Coimbra M.A., Nunes F.M., Passos C.P., Santos S.A.O., Silvestre A.J.D., Silva A.M.N., Rangel M., Domingues M.R.M. (2015) Chlorogenic acid-arabinose hybrid domains in coffee melanoidins: Evidences from a model system. In: Food Chemistry. 185, 135-144.
Coelho E., Rocha M.A.M., Moreira A.S.P., Domingues M.R.M., Coimbra M.A. (2016) Revisiting the structural features of arabinoxylans from brewers' spent grain. In: Carbohydrate Polymers. 139, 167-176.
Ricardo F., Pimentel T., Maciel E., Moreira A.S.P., Domingues M.R., Calado R. (2017) Fatty acid dynamics of the adductor muscle of live cockles (Cerastoderma edule) during their shelf-life and its relevance for traceability of geographic origin. In: Food Control. 77, 192-198.
Nunes F.M., Lopes E.S., Moreira A.S.P., Simoes J., Coimbra M.A., Domingues R.M. (2016) Formation of type 4 resistant starch and maltodextrins from amylose and amylopectin upon dry heating: A model study. In: Carbohydrate Polymers. 141, 253-262.
Moreira A.S.P., Simoes J., Nunes F.M., Evtuguin D.V., Domingues P., Coimbra M.A., Domingues M.R.M. (2016) Nonenzymatic Transglycosylation Reactions Induced by Roasting: New Insights from Models Mimicking Coffee Bean Regions with Distinct Polysaccharide Composition. In: Journal Of Agricultural And Food Chemistry. 64, 8, 1831-1840.
Sarmento A.C., Lopes H., Oliveira C.S., Vitorino R., Samyn B., Sergeant K., Debyser G., van Beeumen J., Domingues P., Amado F., Pires E., Domingues M.R.M., Barros M.T. (2009) Multiplicity of aspartic proteinases from Cynara cardunculus L. In: Planta. 230, 429-439.
Alves E., Melo T., Rey F., Moreira A.S.F., Domingues P., Domingues M.R. (2016) Polar lipid profiling of olive oils as a useful tool in helping to decipher their unique fingerprint. In: Lwt-food Science And Technology. 74, 371-377.
Martins V.M.R., Simoes J., Ferreira I., Cruz M.T., Domingues M.R., Coimbra M.A. (2017) In vitro macrophage nitric oxide production by Pterospartum tridentatum (L.) Willk. inflorescence polysaccharides. In: Carbohydrate Polymers. 157, 176-184.
Auczaj W., Domingues P., Domingues M.R., Pancewicz S., Skrzydlewska E. (2017) Phospholipidomic Analysis Reveals Changes in Sphingomyelin and Lysophosphatidylcholine Profiles in Plasma from Patients with Neuroborreliosis. In: Lipids. 52, 1, 93-98.
Martins A.S., Alves I., Helguero L., Domingues M.R., Neves B.M. (2016) The Unfolded Protein Response in Homeostasis and Modulation of Mammalian Immune Cells. In: International Reviews Of Immunology. 35, 6, 457-476.
Aldini G., Domingues M.R., Spickett C.M., Domingues P., Altomare A., Sanchez-Gomez F.J., Oeste C.L., Perez-Sala D. (2015) Protein lipoxidation: Detection strategies and challenges. In: Redox Biology. 5, 253-266.
Almada M., Domingues M.R., Doria M.L., Fonseca B.M., Teixeira N.A., Correia-da-Silva G. (2015) Lipidomic Approach Towards Deciphering Anandamide Effects in Rat Decidual Cell. In: Journal Of Cellular Physiology. 230, 7, 1549-1557.
Milic I., Melo T., Domingues M.R., Domingues P., Fedorova M. (2015) Heterogeneity of peptide adducts with carbonylated lipid peroxidation products. In: Journal Of Mass Spectrometry. 50, 3, 603-612.
Gudina E.J., Rodrigues A.I., Alves E., Domingues M.R., Teixeira J.A., Rodrigues L.R. (2015) Bioconversion of agro-industrial by-products in rhamnolipids toward applications in enhanced oil recovery and bioremediation. In: Bioresource Technology. 177, 87-93.
Doria M.L., Ribeiro A.S., Wang J., Cotrim C.Z., Domingues P., Williams C., Domingues M.R., Helguero L.A. (2014) Fatty acid and phospholipid biosynthetic pathways are regulated throughout mammary epithelial cell differentiation and correlate to breast cancer survival. In: Faseb Journal. 28, 10, 4247-4264.
Simoes J., Maricato E., Nunes F.M., Domingues M.R., Coimbra M.A. (2014) Thermal stability of spent coffee ground polysaccharides: Galactomannans and arabinogalactans. In: Carbohydrate Polymers. 101, 256-264.
Ferreira R., Guerra G., Padrao A.I., Melo T., Vitorino R., Duarte J.A., Remiao F., Domingues P., Amado F., Domingues M.R. (2013) Lipidomic characterization of streptozotocin-induced heart mitochondrial dysfunction. In: Mitochondrion. 13, 6, 762-771.
Simoes J., Nunes F.M., Domingues M.R., Coimbra M.A. (2013) Extractability and structure of spent coffee ground polysaccharides by roasting pre-treatments. In: Carbohydrate Polymers. 97, 1, 81-89.
Simoes J., Nunes F.M., Domingues P., Coimbra M.A., Domingues M.R. (2012) Mass spectrometry characterization of an Aloe vera mannan presenting immunostimulatory activity. In: Carbohydrate Polymers. 90, 1, 229-236.
Martins J.D., Neves B.M., Goncalo M., Lopes M.C., Domingues M.R., Cruz M.T. (2012) Role of the extra-cellular danger signal adenosine-5 '-triphosphate on the 1-fluoro-2,4-dinitrobenzene-induced maturation of THP-1 cells. In: Journal Of Investigative Dermatology. 132, S116-S116.
Simoes J., Nunes F.M., Domingues M.R., Coimbra M.A. (2011) Demonstration of the presence of acetylation and arabinose branching as structural features of locust bean gum galactomannans. In: Carbohydrate Polymers. 86, 4, 1476-1483.
Ferreira J.A., Pires C., Paulo M., Azevedo N.F., Domingues M.R., Vieira M.J., Monteiro M.A., Coimbra M.A. (2009) Bioaccumulation of Amylose-Like Glycans by Helicobacter pylori. In: Helicobacter. 14, 6, 559-570.
Ferreira N., Cardoso I., Domingues M.R., Vitorino R., Bastos M., Bai G.Y., Saraiva M.J., Almeida M.R. (2009) Binding of epigallocatechin-3-gallate to transthyretin modulates its amyloidogenicity. In: Febs Letters. 583, 22, 3569-3576.
Vilela C., Pinto R.J.B., Coelho J., Domingues M.R.M., Daina S., Sadocco P., Santos S.A.O., Freire C.S.R. (2017) Bioactive chitosan/ellagic acid films with UV-light protection for active food packaging. In: Food Hydrocolloids. 73, 120-128.
Domingues M.R.M., Domingues P., Neves M.G.P.M.S., Tome A.C., Cavaleiro J.A.S. (2009) Recent developments in the structural characterization of substituted meso-tetraarylporphyrins by electrospray tandem mass spectrometry. In: Journal Of Porphyrins And Phthalocyanines. 13, 4-5, 524-527.
Domingues M.R.M., Domingues P., Neves M.G.P.M.S., Tome A.C., Cavaleiro J.A.S. (2009) Recent developments in the structural characterization of substituted meso-tetraarylporphyrins by electrospray tandem mass spectrometry. In: Journal Of Porphyrins And Phthalocyanines. 13, 4-5, 524-527.
Melo T., Domingues P., Ribeiro-Rodrigues T.M., Girao H., Segundo M.A., Domingues M.R.M. (2017) Characterization of phospholipid nitroxidation by LC-MS in biomimetic models and in,H9c2 Myoblast using a lipidomic approach. In: Free Radical Biology And Medicine. 106, 219-227.
Felix L., Oliveira M.M., Videira R., Maciel E., Alves N.D., Nunes F.M., Alves A., Almeida J.M., Domingues M.R.M., Peixoto F.P. (2017) Carvedilol exacerbate gentamicin-induced kidney mitochondrial alterations in adult rat. In: Experimental And Toxicologic Pathology. 69, 2, 83-92.
Silva E.M.P., Melo T., Sousa B.C., Resende D.I.S.P., Magalhaes L.M., Segundo M.A., Silva A.M.S., Domingues M.R.M. (2016) Do cinnamylideneacetophenones have antioxidant properties and a protective effect toward the oxidation of phosphatidylcholines?. In: European Journal Of Medicinal Chemistry. 121, 331-337.
Couto D., Santinha D., Melo T., Ferreira-Fernandes E., Videira R.A., Campos A., Fardilha M., Domingues P., Domingues M.R.M. (2015) Glycosphingolipids and oxidative stress: Evaluation of hydroxyl radical oxidation of galactosyl and lactosylceramides using mass spectrometry. In: Chemistry And Physics Of Lipids. 191, 106-114.
Domingues M.R.M., Marques M.G.O.S., Vale C.A.M., Neves M.G., Cavaleiro J.A.S., Ferrer-Correia A.J., Nemirovskiy O.V., Gross M.L. (1999) Do charge-remote fragmentations occur under matrix-assisted laser desorption ionization post-source decompositions and matrix-assisted laser desorption ionization collisionally activated decompositions?. In: Journal Of The American Society For Mass Spectrometry. 10, 3, 217-223.
Domingues M.R.M., Santana-Marques M.G., Ferrrer-Correia A.J., Tome A.C., Neves M.G.P.M.S., Cavaleiro J.A.S. (1999) Liquid secondary ion mass spectrometry and collision-induced dissociation mass spectrometry of sulfonamide derivatives of meso-tetraphenylporphyrin. In: Journal Of Porphyrins And Phthalocyanines. 3, 3, 172-179.
Domingues M.R.M., Domingues P., Gajewski M., Czuchajowski L., Ferrer-Correia A.J. (2001) Electrospray tandem mass spectrometry of lexitropsins. In: Rapid Communications In Mass Spectrometry. 15, 12, 908-914.
Domingues M.R.M., Santana-Marques M.G.O., Domingues P., Faustino M.A., Neves M.G.P.M.S., Cavaleiro J.A.S., Ferrer-Correia A.J. (2000) Liquid secondary ion mass spectrometry of porphyrin dimers: reduction reactions and structural characterisation. In: Rapid Communications In Mass Spectrometry. 14, 21, 2025-2029.
Reis A., Domingues M.R.M., Ferrer-Correia A.J., Coimbra M.A. (2003) Structural characterisation by MALDI-MS of olive xylo-oligosaccharides obtained by partial acid hydrolysis. In: Carbohydrate Polymers. 53, 1, 101-107.
Domingues M.R.M., Domingues P., Reis A., Fonseca C., Amado F.M.L., Ferrer-Correia A.J.V. (2003) Identification of oxidation products and free radicals of tryptophan by mass spectrometry. In: Journal Of The American Society For Mass Spectrometry. 14, 4, 406-416.
Lemos M.A., Teixeira J.A., Domingues M.R.M., Mota M., Gama F.M. (2003) The enhancement of the cellulolytic activity of cellobiohydrolase I and endoglucanase by the addition of cellulose binding domains derived from Trichoderma reesei. In: Enzyme And Microbial Technology. 32, 1, 35-40.
Domingues M.R.M., Marques M.G.O.S., Alonso C.M.A., Neves M.G.P.M.S., Cavaleiro J.A.S., Ferrer-Correia A.J., Nemirovskiy O.V., Gross M.L. (2002) Unexpected fragmentation of beta-substituted meso-tetraphenylporphyrins induced by high-energy collisional activation. In: Journal Of The American Society For Mass Spectrometry. 13, 12, 1427-1431.
Reis A., Coimbra M.A., Domingues P., Ferrer-Correia A.J., Domingues M.R.M. (2002) Structural characterisation of underivatised olive pulp xylo-oligosaccharides by mass spectrometry using matrix-assisted laser desorption/ionisation and electrospray ionisation. In: Rapid Communications In Mass Spectrometry. 16, 22, 2124-2132.
Domingues M.R.M., Domingues P., Reis A., Correia A.J.F., Tome J.P.C., Tome A.C., Neves M.G.P.M.S., Cavaleiro J.A.S. (2004) Structural characterization of glycoporphyrins by electrospray tandem mass spectrometry. In: Journal Of Mass Spectrometry. 39, 2, 158-167.
Reis A., Pinto P., Coimbra M.A., Evtuguin D.V., Neto C.P., Correia A.J.F., Domingues M.R.M. (2004) Structural differentiation of uronosyl substitution patterns in acidic heteroxylans by electrospray tandem mass spectrometry. In: Journal Of The American Society For Mass Spectrometry. 15, 1, 43-47.
Reis A., Domingues P., Ferrer-Correia A.J.V., Domingues M.R.M. (2004) Identification by electrospray tandem mass spectrometry of spin-trapped free radicals from oxidized 2-oleoyl-1-palmitoyl-sn-glycero-3-phosphocholine. In: Rapid Communications In Mass Spectrometry. 18, 10, 1047-1058.
Reis A., Domingues P., Ferrer-Correia A.J.V., Domingues M.R.M. (2004) Fragmentation study of short-chain products derived from oxidation of diacylphosphatidylcholines by electrospray tandem mass spectrometry: identification of novel short-chain products. In: Rapid Communications In Mass Spectrometry. 18, 23, 2849-2858.
Domingues M.R.M., Domingues P., Oliveira M.M., Carvalho L.H.M., Oliveira-Campos A.F., Correia A.J.F. (2004) Electrospray tandem mass spectrometry of 2H-chromenes. In: Rapid Communications In Mass Spectrometry. 18, 24, 2969-2975.
Guedes S.D., Vitorino R., Tomer K., Domingues M.R.M., Correia A.J.F., Amado F., Domingues P. (2003) Drosophila melanogaster larval hemolymph protein mapping. In: Biochemical And Biophysical Research Communications. 312, 3, 545-554.
Reis A., Domingues M.R.M., Amado F.M.L., Ferrer-Correia A.J.V., Domingues P. (2003) Detection and characterization by mass spectrometry of radical adducts produced by linoleic acid oxidation. In: Journal Of The American Society For Mass Spectrometry. 14, 11, 1250-1261.
Reis A., Domingues M.R.M., Domingues P., Ferrer-Correia A.J., Coimbra M.A. (2003) Positive and negative electrospray ionisation tandem mass spectrometry as a tool for structural characterisation of acid released oligosaccharides from olive pulp glucuronoxylans. In: Carbohydrate Research. 338, 14, 1497-1505.
Serra V.V., Domingues M.R.M., Faustino M.A.F., Domingues P., Tome J.P.C., Neves M.G.P.M.S., Tome A.C., Cavaleiro J.A.S., Ferrer-Correia A.J. (2005) Electrospray tandem mass spectrometry of new porphyrin amino acid conjugates. In: Rapid Communications In Mass Spectrometry. 19, 18, 2569-2580.
Reis A., Pinto P., Evtuguin D.V., Neto C.P., Domingues P., Ferrer-Correia A.J., Domingues M.R.M. (2005) Electrospray tandem mass spectrometry of underivatised acetylated xylo-oligosaccharides. In: Rapid Communications In Mass Spectrometry. 19, 23, 3589-3599.
Reis A., Domingues P., Ferrer-Correia A.J.V., Domingues M.R.M. (2004) Tandem mass spectrometry of intact oxidation products of diacylphosphatidylcholines: evidence for the occurrence of the oxidation of the phosphocholine head and differentiation of isomers. In: Journal Of Mass Spectrometry. 39, 12, 1513-1522.
Reis A., Coimbra M.A., Domingues P., Ferrer-Correia A.J., Domingues M.R.M. (2004) Fragmentation pattern of underivatised xylo-oligosaccharides and their alditol derivatives by electrospray tandem mass spectrometry. In: Carbohydrate Polymers. 55, 4, 401-409.
Zhao S.X., Neves M.G.P.M.S., Tome A.C., Silva A.M.S., Cavaleiro J.A.S., Domingues M.R.M., Correia A.J.F. (2005) Reaction of meso-tetraarylporphyrins with pyrazine ortho-quinodimethanes. In: Tetrahedron Letters. 46, 13, 2189-2191.
Reis A., Domingues M.R.M., Amado F.M.L., Ferrer-Correia A.J.V., Domingues P. (2005) Separation of peroxidation products of diacyl-phosphatidylcholines by reversed-phase liquid chromatography-mass spectrometry. In: Biomedical Chromatography. 19, 2, 129-137.
Silva E.M.P., Domingues M.R.M., Barros C., Faustino M.A.F., Tome J.P.C., Neves M.G.P.M.S., Tome A.C., Santana-Marques M.G.S., Cavaleiro J.A.S., Ferrer-Correia A.J. (2005) Characterization of dinitroporphyrin zinc complexes by electrospray ionization tandem mass spectrometry. Unusual fragmentations of beta-(1,3-dinitroalkyl) porphyrins. In: Journal Of Mass Spectrometry. 40, 1, 117-122.
Nunes F.M., Reis A., Domingues M.R.M., Coimbra M.A. (2006) Characterization of galactomannan derivatives in roasted coffee beverages. In: Journal Of Agricultural And Food Chemistry. 54, 9, 3428-3439.
Reis A., Domingues P., Ferrer-Correia A.J.V., Domingues M.R.M. (2006) Peptide-phospholipid cross-linking reactions: Identification of leucine enkephalin-alka(a)nal-glycerophosphatidylcholine adducts by tandem mass spectrometry. In: Journal Of The American Society For Mass Spectrometry. 17, 5, 657-660.
Reis A., Domingues M.R.M., Amado F.M.L., Ferrer-Correia A.J.V., Domingues P. (2006) Identification of linoleic acid free radicals and other breakdown products using spin trapping with liquid chromatography-electrospray tandem mass spectrometry. In: Biomedical Chromatography. 20, 1, 109-118.
Silva E.M.P., Serra V.V., Ribeiro A.O., Tome J.P.C., Domingues P., Faustino M.A.F., Neves M.G.P.M.S., Tome A.C., Cavaleiro J.A.S., Ferrer-Correia A.J., Iamamoto Y., Domingues M.R.M. (2006) Characterization of cationic glycoporphyrins by electrospray tandem mass spectrometry. In: Rapid Communications In Mass Spectrometry. 20, 23, 3605-3611.
Passos C.P., Cardoso S.M., Domingues M.R.M., Domingues P., Silva C.M., Coimbra M.A. (2007) Evidence for galloylated type-A procyanidins in grape seeds. In: Food Chemistry. 105, 4, 1457-1467.
Reis A., Domingues P., Ferrer-Correia A.J.V., Domingues M.R.M. (2007) Identification of free radicals of glycerophosphatidylcholines containing omega-6 fatty acids using spin trapping coupled with tandem mass spectrometry. In: Free Radical Research. 41, 4, 432-443.
Reis A., Domingues M.R.M., Amado F.M.L., Ferrer-Correia A.J., Domingues P. (2007) Radical peroxidation of palmitoyl-lineloyl-glycerophosphocholine liposomes: Identification of long-chain oxidised products by liquid chromatography-tandem mass spectrometry. In: Journal Of Chromatography B-analytical Technologies In The Biomedical And Life Sciences. 855, 2, 186-199.
Silva J.N., Silva A.M.G., Tome J.P., Ribeiro A.O., Domingues M.R.M., Cavaleiro J.A.S., Silva A.M.S., Graca M., Neves M.G.P.M.S., Tome A.C., Serra O.A., Bosca F., Filipe P., Santuse R., Morliere P. (2008) Photophysical properties of a photocytotoxic fluorinated chlorin conjugated to four beta-cyclodextrins. In: Photochemical & Photobiological Sciences. 7, 7, 834-843.
Graca G., Duarte I.F., Goodfellow B.J., Carreira I.M., Couceiro A.B., Domingues M.D., Spraul M., Tseng L.H., Gil A.M. (2008) Metabolite profiling of human amniotic fluid by hyphenated nuclear magnetic resonance spectroscopy. In: Analytical Chemistry. 80, 15, 6085-6092.
Reis A., Domingues M.R.M., Amado F.M.L., Oliveira M.M., Domingues P. (2008) Detection and characterization of cyclic hydroxylamine adducts by mass spectrometry. In: Free Radical Research. 42, 5, 481-491.
Nunes F.M., Reis A., Silva A.M.S., Domingues M.R.M., Coimbra M.A. (2008) Rhamnoarabinosyl and rhamnoarabinoarabinosyl side chains as structural features of coffee arabinogalactans. In: Phytochemistry. 69, 7, 1573-1585.
Barros A.I.R.N.A., Nunes F.M., Barros C., Silva A.M.S., Domingues M.R.M. (2009) Structural characterization of nitrated 2 '-hydroxychalcones by electrospray ionization tandem mass spectrometry. In: European Journal Of Mass Spectrometry. 15, 5, 605-616.
Reis A., Domingues M.R.M., Oliveira M.M., Domingues P. (2009) Identification of free radicals by spin trapping with DEPMPO and MCPIO using tandem mass spectrometry. In: European Journal Of Mass Spectrometry. 15, 6, 689-703.
Simoes C., Simoes V., Reis A., Domingues P., Domingues M.R.M. (2008) Determination of the fatty acyl profiles of phosphatidylethanolamines by tandem mass spectrometry of sodium adducts. In: Rapid Communications In Mass Spectrometry. 22, 20, 3238-3244.
Simoes C., Simoes V., Reis A., Domingues P., Domingues M.R.M. (2008) Determination of the fatty acyl profiles of phosphatidylethanolamines by tandem mass spectrometry of sodium adducts. In: Rapid Communications In Mass Spectrometry. 22, 20, 3238-3244.
Fonseca C., Domingues P., Reis A., Domingues M.R.M. (2008) Identification of leucine-enkephalin radical oxidation products by liquid chromatography tandem mass spectrometry. In: Biomedical Chromatography. 22, 9, 947-959.
Fonseca C., Domingues P., Reis A., Domingues M.R.M. (2008) Identification of leucine-enkephalin radical oxidation products by liquid chromatography tandem mass spectrometry. In: Biomedical Chromatography. 22, 9, 947-959.
Fonseca C., Domingues M.R.M., Simoes C., Amado F., Domingues P. (2009) Reactivity of Tyr-Leu and Leu-Tyr dipeptides: identification of oxidation products by liquid chromatography-tandem mass spectrometry. In: Journal Of Mass Spectrometry. 44, 5, 681-693.
Simoes J., Madureira P., Nunes F.M., Domingues M.D., Vilanova M., Coimbra M.A. (2009) Immunostimulatory properties of coffee mannans. In: Molecular Nutrition & Food Research. 53, 8, 1036-1043.
Guedes S., Vitorino R., Domingues M.R.M., Amado F., Domingues P. (2009) Mass Spectrometry Characterization of the Glycation Sites of Bovine Insulin by Tandem Mass Spectrometry. In: Journal Of The American Society For Mass Spectrometry. 20, 7, 1319-1326.
Guedes S., Neves B., Vitorino R., Domingues R., Cruz M.T., Domingues P. (2017) Contact dermatitis: in pursuit of sensitizer's molecular targets through proteomics. In: Archives Of Toxicology. 91, 2, 811-825.
Laranjeira P., Gomes J., Pedreiro S., Pedrosa M., Martinho A., Antunes B., Ribeiro T., Santos F., Domingues R., Abecasis M., Trindade H., Paiva A. (2015) Human Bone Marrow-Derived Mesenchymal Stromal Cells Differentially Inhibit Cytokine Production by Peripheral Blood Monocytes Subpopulations and Myeloid Dendritic Cells. In: Stem Cells International.
Almada M., Domingues R., Doria L., Fonseca B., Teixeira N., da Silva G.C. (2014) Lipidomic profiling of anandamide effects on decidual metabolic pathways. In: Febs Journal. 281, 201-201.
Archer A., Stolarczyk E., Doria M.L., Helguero L., Domingues R., Howard J.K., Mode A., Korach-Andre M., Gustafsson J.A. (2013) LXR activation by GW3965 alters fat tissue distribution and adipose tissue inflammation in ob/ob female mice. In: Journal Of Lipid Research. 54, 5, 1300-1311.
Maina N.H., Juvonen M., Domingues R.M., Virkki L., Jokela J., Tenkanen M. (2013) Structural analysis of linear mixed-linkage glucooligosaccharides by tandem mass spectrometry. In: Food Chemistry. 136, 3-4, 1496-1507.
Coelho E., Reis A., Domingues R.M., Rocha S.M., Coimbra M.A. (2011) Synergistic Effect of High and Low Molecular Weight Molecules in the Foamability and Foam Stability of Sparkling Wines. In: Journal Of Agricultural And Food Chemistry. 59, 7, 3168-3179.
Guedes S., Vitorino R., Domingues R., Amado F., Domingues P. (2009) Oxidation of bovine serum albumin: identification of oxidation products and structural modifications. In: Rapid Communications In Mass Spectrometry. 23, 15, 2307-2315.
Simoes J., Domingues P., Reis A., Nunes F.M., Coimbra M.A., Domingues R.M. (2007) Identification of anomeric configuration of underivatized reducing glucopyranosyl-glucose Disaccharides by tandem mass Spectrometry and Multivariate analysis. In: Analytical Chemistry. 79, 15, 5896-5905.
Guedes S.D., Vitorino R., Domingues R., Tomer K., Correia A.J.F., Amado F., Domingues P. (2005) Proteomics of immune-challenged Drosophila melanogaster larvae hemolymph. In: Biochemical And Biophysical Research Communications. 328, 1, 106-115.
Neri D.F.M., Balcao V.M., Cardoso S.M., Silva A.M.S., Domingues M.D.M., Torres D.P.M., Rodrigues L.R.M., Carvalho L.B., Teixeira J.A.C. (2011) Characterization of galactooligosaccharides produced by beta-galactosidase immobilized onto magnetized Dacron. In: International Dairy Journal. 21, 3, 172-178.
Maciel E., Domingues P., Domingues M.R.M. (2011) Liquid chromatography/tandem mass spectrometry analysis of long-chain oxidation products of cardiolipin induced by the hydroxyl radical. In: Rapid Communications In Mass Spectrometry. 25, 2, 316-326.
Ferreira J.A., Domingues M.R.M., Reis A., Figueiredo C., Monteiro M.A., Coimbra M.A. (2011) Aldobiouronic acid domains in Helicobacter pylori. In: Carbohydrate Research. 346, 5, 638-643.
Guedes S., Vitorino R., Domingues M.R.M., Amado F., Domingues P. (2011) Glycation and oxidation of histones H2B and H1: in vitro study and characterization by mass spectrometry. In: Analytical And Bioanalytical Chemistry. 399, 10, 3529-3539.
Maciel E., Domingues P., Marques D., Simoes C., Reis A., Oliveira M.M., Videira R.A., Peixoto F., Domingues M.R.M. (2011) Cardiolipin and oxidative stress: Identification of new short chain oxidation products of cardiolipin in in vitro analysis and in nephrotoxic drug-induced disturbances in rat kidney tissue. In: International Journal Of Mass Spectrometry. 301, 1-3, 62-73.
Reis A., Fonseca C., Maciel E., Domingues P., Domingues M.R.M. (2011) Influence of amino acid relative position on the oxidative modification of histidine and glycine peptides. In: Analytical And Bioanalytical Chemistry. 399, 8, 2779-2794.
Silva A.M.N., Borralho A.C., Pinho S.A., Domingues M.R.M., Domingues P. (2011) Cross-oxidation of angiotensin II by glycerophosphatidylcholine oxidation products. In: Rapid Communications In Mass Spectrometry. 25, 10, 1413-1421.
Gomes A.T.P.C., Cunha A.C., Domingues M.D.M., Neves M.G.P.M.S., Tome A.C., Silva A.M.S., Santos F.D., Souza M.C.B.V., Ferreira V.F., Cavaleiro J.A.S. (2011) Synthesis and characterization of new porphyrin/4-quinolone conjugates. In: Tetrahedron. 67, 38, 7336-7342.
Santos S.A.O., Freire C.S.R., Domingues M.R.M., Silvestre A.J.D., Neto C.P. (2011) Characterization of Phenolic Components in Polar Extracts of Eucalyptus globulus Labill. Bark by High-Performance Liquid Chromatography-Mass Spectrometry. In: Journal Of Agricultural And Food Chemistry. 59, 17, 9386-9393.
Cardoso S.M., Falcao S.I., Peres A.M., Domingues M.R.M. (2011) Oleuropein/ligstroside isomers and their derivatives in Portuguese olive mill wastewaters. In: Food Chemistry. 129, 2, 291-296.
Villaverde J.J., Santos S.A.O., Simoes M.M.Q., Neto C.P., Domingues M.R.M., Silvestre A.J.D. (2011) Analysis of linoleic acid hydroperoxides generated by biomimetic and enzymatic systems through an integrated methodology. In: Industrial Crops And Products. 34, 3, 1474-1481.
Resende D.I.S.P., Silva E.M.P., Barros C., Domingues M.R.M., Silva A.M.S., Cavaleiro J.A.S. (2011) Tandem mass spectrometry based investigation of cinnamylideneacetophenone derivatives: valuable tool for the differentiation of positional isomers. In: Rapid Communications In Mass Spectrometry. 25, 20, 3185-3195.
Maciel E., da Silva R.N., Simoes C., Domingues P., Domingues M.R.M. (2011) Structural Characterization of Oxidized Glycerophosphatidylserine: Evidence of Polar Head Oxidation. In: Journal Of The American Society For Mass Spectrometry. 22, 10, 1804-1814.
Silva A.M.G., Leite A., Gonzalez P., Domingues M.R.M., Gameiro P., de Castro B., Rangel M. (2011) Use of a porphyrin platform and 3,4-HPO chelating units to synthesize ligands with N-4 and O-4 coordination sites. In: Tetrahedron. 67, 40, 7821-7828.
Nunes C., Silva L., Fernandes A.P., Guine R.P.F., Domingues M.R.M., Coimbra M.A. (2012) Occurrence of cellobiose residues directly linked to galacturonic acid in pectic polysaccharides. In: Carbohydrate Polymers. 87, 1, 620-626.
Pereira J.F.B., Gudina E.J., Doria M.L., Domingues M.R., Rodrigues L.R., Teixeira J.A., Coutinho J.A.P. (2012) Characterization by electrospray ionization and tandem mass spectrometry of rhamnolipids produced by two Pseudomonas aeruginosa strains isolated from Brazilian crude oil. In: European Journal Of Mass Spectrometry. 18, 4, 399-406.
Ferreira F.M., Dinis L.T., Azedo P., Galhano C.I.C., Simoes A., Cardoso S.M., Domingues M.R.M., Pereira O.R., Palmeira C.M., Peixoto F.P. (2012) Antioxidant capacity and toxicological evaluation of Pterospartum tridentatum flower extracts. In: Cyta-journal Of Food. 10, 2, 92-102.
Neves C.M.B., Simoes M.M.Q., Domingues M.R.M., Santos I.C.M.S., Neves M.G.P.M.S., Paz F.A.A., Silva A.M.S., Cavaleiro J.A.S. (2012) Oxidation of diclofenac catalyzed by manganese porphyrins: synthesis of novel diclofenac derivatives. In: Rsc Advances. 2, 19, 7427-7438.
Pereira O.R., Silva A.M.S., Domingues M.R.M., Cardoso S.M. (2012) Identification of phenolic constituents of Cytisus multiflorus. In: Food Chemistry. 131, 2, 652-659.
Melo T., Videira R.A., Andre S., Maciel E., Francisco C.S., Oliveira-Campos A.M., Rodrigues L.M., Domingues M.R.M., Peixoto F., Oliveira M.M. (2012) Tacrine and its analogues impair mitochondrial function and bioenergetics: a lipidomic analysis in rat brain. In: Journal Of Neurochemistry. 120, 6, 998-1013.
Jalali H.T., Petronilho S., Villaverde J.J., Coimbra M.A., Domingues M.R.M., Ebrahimian Z.J., Silvestre A.J.D., Rocha S.M. (2012) Deeper insight into the monoterpenic composition of Ferula gummosa oleo-gum-resin from Iran. In: Industrial Crops And Products. 36, 1, 500-507.
Villaverde J.J., Santos S.A.O., Maciel E., Simoes M.M.Q., Neto C.P., Domingues M.R.M., Silvestre A.J.D. (2012) Formation of oligomeric alkenylperoxides during the oxidation of unsaturated fatty acids: an electrospray ionization tandem mass spectrometry study. In: Journal Of Mass Spectrometry. 47, 2, 163-172.
Loureiro P.E.G., Domingues M.R.M., Fernandes A.J.S., Carvalho M.G.V.S., Evtuguin D.V. (2012) Discriminating the brightness stability of cellulosic pulp in relation to the final bleaching stage. In: Carbohydrate Polymers. 88, 2, 726-733.
Santinha D.R., Marques D.R., Maciel E.A., Simoes C.S.O., Rosa S., Neves B.M., Macedo B., Domingues P., Cruz M.T., Domingues M.R.M. (2012) Profiling changes triggered during maturation of dendritic cells: a lipidomic approach. In: Analytical And Bioanalytical Chemistry. 403, 2, 457-471.
Monteiro J.P., Pereira C., Maciel E., Baldeiras I., Peixoto F., Domingues M.R., Jurado A.S., Oliveira P.J. (2012) Rapeseed oil-based diet alters rat hepatic mitochondria physiology and membrane composition. In: European Journal Of Clinical Investigation. 42, 74-74.
Reis A., Fonseca C., Domingues M.R.M., Domingues P. (2009) Oxidative studies in histidine peptide models: is the oxidative pathway influenced by the relative position of the amino acid?. In: Free Radical Research. 43, 68-68.
Pereira O.R., Domingues M.R.M., Silva A.M.S., Cardoso S.M. (2012) Phenolic constituents of Lamium album: Focus on isoscutellarein derivatives. In: Food Research International. 48, 1, 330-335.
Melo T., Maciel E., Oliveira M.M., Domingues P., Domingues M.R.M. (2012) Study of sphingolipids oxidation by ESI tandem MS. In: European Journal Of Lipid Science And Technology. 114, 7, 726-732.
Doria M.L., Cotrim Z., Macedo B., Simoes C., Domingues P., Helguero L., Domingues M.R. (2012) Lipidomic approach to identify patterns in phospholipid profiles and define class differences in mammary epithelial and breast cancer cells. In: Breast Cancer Research And Treatment. 133, 2, 635-648.
Silva E.M.P., Domingues M.R.M., Silva A.M.S., Cavaleiro J.A.S. (2012) Characterisation of (E)-2-styrylchromones by electrospray ionisation mass spectrometry: singular gas-phase formation of benzoxanthenones. In: Rapid Communications In Mass Spectrometry. 26, 19, 2251-2259.
da Silva R.N., Silva A.C., Maciel E., Simoes C., Horta S., Laranjeira P., Paiva A., Domingues P., Domingues M.R.M. (2012) Evaluation of the capacity of oxidized phosphatidylserines to induce the expression of cytokines in monocytes and dendritic cells. In: Archives Of Biochemistry And Biophysics. 525, 1, 9-15.
Moreira A.S.P., Nunes F.M., Domingues M.R., Coimbra M.A. (2012) Coffee melanoidins: structures, mechanisms of formation and potential health impacts. In: Food & Function. 3, 9, 903-915.
Santos S.A.O., Villaverde J.J., Freire C.S.R., Domingues M.R.M., Neto C.P., Silvestre A.J.D. (2012) Phenolic composition and antioxidant activity of Eucalyptus grandis, E. urograndis (E. grandis x E. urophylla) and E. maidenii bark extracts. In: Industrial Crops And Products. 39, 120-127.
Jalali H.T., Petronilho S., Villaverde J.J., Coimbra M.A., Domingues M.R.M., Ebrahimian Z.J., Silvestre A.J.D., Rocha S.M. (2013) Assessment of the sesquiterpenic profile of Ferula gummosa oleo-gum-resin (galbanum) from Iran. Contributes to its valuation as a potential source of sesquiterpenic compounds. In: Industrial Crops And Products. 44, 185-191.
Ershova O., da Costa E.V., Fernandes A.J.S., Domingues M.R., Evtuguin D.V., Sixta H. (2012) Effect of urea on cellulose degradation under conditions of alkaline pulping. In: Cellulose. 19, 6, 2195-2204.
Ferreira N., Santos S.A.O., Domingues M.R.M., Saraiva M.J., Almeida M.R. (2013) Dietary curcumin counteracts extracellular transthyretin deposition: Insights on the mechanism of amyloid inhibition. In: Biochimica Et Biophysica Acta-molecular Basis Of Disease. 1832, 1, 39-45.
Silva A.M.N., Marcal S.L., Vitorino R., Domingues M.R.M., Domingues P. (2013) Characterization of in vitro protein oxidation using mass spectrometry: A time course study of oxidized alpha-amylase. In: Archives Of Biochemistry And Biophysics. 530, 1, 23-31.
Villaverde J.J., van der Vlist V., Santos S.A.O., Haarmann T., Langfelder K., Pirttimaa M., Nyyssola A., Jylha S., Tamminen T., Kruus K., de Graaff L., Neto C.P., Simoes M.M.Q., Domingues M.R.M., Silvestre A.J.D., Eidner J., Buchert J. (2013) Hydroperoxide production from linoleic acid by heterologous Gaeumannomyces graminis tritici lipoxygenase: Optimization and scale-up. In: Chemical Engineering Journal. 217, 82-90.
Menezes J.C.J.M.D.S., Neves M.G.P.M.S., Cavaleiro J.A.S., Barros C., Santos S.M., da Silva F.D., Ferreira V.F., Domingues M.R.M. (2013) Gas phase reactions of beta-substituted hetero-Diels-Alder adducts of meso-tetraphenylporphyrin using tandem mass spectrometry. In: International Journal Of Mass Spectrometry. 343, 1-8.
Soares A.R.M., Neves M.G.P.M.S., Santos S.M., Tome J.P.C., Tome A.C., Cavaleiro J.A.S., Torres T., Domingues M.R.M. (2013) Glycophthalocyanines: structural differentiation and isomeric differentiation by matrix-assisted laser desorption/ionization tandem mass spectrometry. In: Rapid Communications In Mass Spectrometry. 27, 9, 1019-1026.
Santinha D.R., Doria M.L., Neves B.M., Maciel E.A., Martins J., Helguero L., Domingues P., Cruz M.T., Domingues M.R. (2013) Prospective phospholipid markers for skin sensitization prediction in keratinocytes: A phospholipidomic approach. In: Archives Of Biochemistry And Biophysics. 533, 1-2, 33-41.
Filipe O.M.S., Santos S.A.O., Domingues M.R.M., Vidal M.M., Silvestre A.J.D., Neto C.P., Santos E.B.H. (2013) Photodegradation of the fungicide thiram in aqueous solutions. Kinetic studies and identification of the photodegradation products by HPLC-MS/MS. In: Chemosphere. 91, 7, 993-1001.
Falcao S.I., Vale N., Gomes P., Domingues M.R.M., Freire C., Cardoso S.M., Vilas-Boas M. (2013) Phenolic Profiling of Portuguese Propolis by LC-MS Spectrometry: Uncommon Propolis Rich in Flavonoid Glycosides. In: Phytochemical Analysis. 24, 4, 309-318.
Menezes J.C.J.M.D.S., Cavaleiro J.A.S., Kamat S.P., Barros C.M.R.F., Domingues M.R.M. (2013) Electrospray tandem mass spectrometry analysis of methylenedioxy chalcones, flavanones and flavones. In: Rapid Communications In Mass Spectrometry. 27, 12, 1303-1310.
Menezes J.C.J.M.D.S., Cavaleiro J.A.S., Kamat S.P., Barros C.M.R.F., Domingues M.R.M. (2013) Electrospray tandem mass spectrometry analysis of methylenedioxy chalcones, flavanones and flavones. In: Rapid Communications In Mass Spectrometry. 27, 12, 1303-1310.
Santos A.L., Moreirinha C., Lopes D., Esteves A.C., Henriques I., Almeida A., Domingues M.R.M., Delgadillo I., Correia A., Cunha A. (2013) Effects of UV Radiation on the Lipids and Proteins of Bacteria Studied by Mid-Infrared Spectroscopy. In: Environmental Science & Technology. 47, 12, 6306-6315.
Maciel E., Faria R., Santinha D., Domingues M.R.M., Domingues P. (2013) Evaluation of oxidation and glyco-oxidation of 1-palmitoyl-2-arachidonoyl-phosphatidylserine by LC-MS/MS. In: Journal Of Chromatography B-analytical Technologies In The Biomedical And Life Sciences. 929, 76-83.
Moreira A.S.P., Coimbra M.A., Nunes F.M., Domingues M.R.M. (2013) Roasting-induced changes in arabinotriose, a model of coffee arabinogalactan side chains. In: Food Chemistry. 138, 4, 2291-2299.
Maciel E., da Silva R.N., Simoes C., Melo T., Ferreira R., Domingues P., Domingues M.R.M. (2013) Liquid chromatography-tandem mass spectrometry of phosphatidylserine advanced glycated end products. In: Chemistry And Physics Of Lipids. 174, 1-7.
Villaverde J.J., Santos S.A.O., Haarmann T., Neto C.P., Simoes M.M.Q., Domingues M.R.M., Silvestre A.J.D. (2013) Cloned Pseudomonas aeruginosa lipoxygenase as efficient approach for the clean conversion of linoleic acid into valuable hydroperoxides. In: Chemical Engineering Journal. 231, 519-525.
Alves E., Melo T., Simoes C., Faustino M.A.F., Tome J.P.C., Neves M.G.P.M.S., Cavaleiro J.A.S., Cunha A., Gomes N.C.M., Domingues P., Domingues M.R.M., Almeida A. (2013) Photodynamic oxidation of Staphylococcus warneri membrane phospholipids: new insights based on lipidomics. In: Rapid Communications In Mass Spectrometry. 27, 14, 1607-1618.
Menezes J.C.J.M.D.S., Cavaleiro J.A.S., Domingues M.R.M. (2013) Structural analysis of 2-arylidene-1-indanone derivatives by electrospray ionization tandem mass spectrometry. In: Rapid Communications In Mass Spectrometry. 27, 21, 2461-2471.
Reis A., Domingues P., Domingues M.R.M. (2013) Structural motifs in primary oxidation products of palmitoyl-arachidonoyl-phosphatidylcholines by LC-MS/MS. In: Journal Of Mass Spectrometry. 48, 11, 1207-1216.
Simoes C., Silva A.C., Domingues P., Laranjeira P., Paiva A., Domingues M.R.M. (2013) Modified phosphatidylethanolamines induce different levels of cytokine expression in monocytes and dendritic cells. In: Chemistry And Physics Of Lipids. 175, 57-64.
Simoes C., Silva A.C., Domingues P., Laranjeira P., Paiva A., Domingues M.R.M. (2013) Modified phosphatidylethanolamines induce different levels of cytokine expression in monocytes and dendritic cells. In: Chemistry And Physics Of Lipids. 175, 57-64.
Pinto J., Domingues M.R.M., Galhano E., Pita C., Almeida M.D., Carreira I.M., Gil A.M. (2014) Human plasma stability during handling and storage: impact on NMR metabolomics. In: Analyst. 139, 5, 1168-1177.
Silva A.M.N., Vitorino R., Domingues M.R.M., Spickett C.M., Domingues P. (2013) Post-translational Modifications and Mass Spectrometry Detection. In: Free Radical Biology And Medicine. 65, 925-941.
Monteiro J.P., Pereira C.V., Silva A.M., Maciel E., Baldeiras I., Peixoto F., Domingues M.R., Jurado A.S., Oliveira P.J. (2013) Rapeseed oil-rich diet alters hepatic mitochondrial membrane lipid composition and disrupts bioenergetics. In: Archives Of Toxicology. 87, 12, 2151-2163.
Pereira O.R., Peres A.M., Silva A.M.S., Domingues M.R.M., Cardoso S.M. (2013) Simultaneous characterization and quantification of phenolic compounds in Thymus x citriodorus using a validated HPLC-UV and ESI-MS combined method. In: Food Research International. 54, 2, 1773-1780.
Melo T., Santos N., Lopes D., Alves E., Maciel E., Faustino M.A.F., Tome J.P.C., Neves M.G.P.M.S., Almeida A., Domingues P., Segundo M.A., Domingues M.R.M. (2013) Photosensitized oxidation of phosphatidylethanolamines monitored by electrospray tandem mass spectrometry. In: Journal Of Mass Spectrometry. 48, 12, 1357-1365.
Serdechnova M., Ivanov V.L., Domingues M.R.M., Evtuguin D.V., Ferreira M.G.S., Zheludkevich M.L. (2014) Photodegradation of 2-mercaptobenzothiazole and 1,2,3-benzotriazole corrosion inhibitors in aqueous solutions and organic solvents. In: Physical Chemistry Chemical Physics. 16, 45, 25152-25160.
Gouveia D.D., Silva A.M.N., Vitorino R., Domingues M.R.M., Domingues P. (2014) Efficiency of trypsin digestion for mass-spectrometry-based identification and quantification of oxidized proteins: evaluation of the digestion of oxidized bovine serum albumin. In: European Journal Of Mass Spectrometry. 20, 3, 271-278.
Iglesias B.A., Barata J.F.B., Domingues M.R.M., Neves M.G.P.M.S., Cavaleiro J.A.S. (2014) The gas-phase fragmentation behavior of protonated meso-trans-A(2)B-corroles studied by ESI-MS/MS: The influence of the meso-10-aryl substituent. In: International Journal Of Mass Spectrometry. 363, 1-7.
Maciel E., Neves B.M., Santinha D., Reis A., Domingues P., Cruz M.T., Pitt A.R., Spickett C.M., Domingues M.R.M. (2014) Detection of phosphatidylserine with a modified polar head group in human keratinocytes exposed to the radical generator AAPH. In: Archives Of Biochemistry And Biophysics. 548, 38-45.
Maciel E., Felgueiras J., Silva E.M.P., Ricardo F., Moreira A.S.P., Melo T., Campos A., Fardilha M., Domingues P., Domingues M.R. (2017) Lipid remodelling in human melanoma cells in response to UVA exposure. In: Photochemical & Photobiological Sciences. 16, 5, 744-752.
Moreira A.S.P., Nunes F.M., Simoes C., Maciel E., Domingues P., Domingues M.R.M., Coimbra M.A. (2017) Transglycosylation reactions, a main mechanism of phenolics incorporation in coffee melanoidins: Inhibition by Maillard reaction. In: Food Chemistry. 227, 422-431.
Alves E., Santos N., Melo T., Maciel E., Doria M.L., Faustino M.A.F., Tome J.P.C., Neves M.G.P.M.S., Cavaleiro J.A.S., Cunha A., Helguero L.A., Domingues P., Almeida A., Domingues M.R.M. (2013) Photodynamic oxidation of Escherichia coli membrane phospholipids: new insights based on lipidomics. In: Rapid Communications In Mass Spectrometry. 27, 23, 2717-2728.
Passos C.P., Moreira A.S.P., Domingues M.R.M., Evtuguin D.V., Coimbra M.A. (2014) Sequential microwave superheated water extraction of mannans from spent coffee grounds. In: Carbohydrate Polymers. 103, 333-338.
Andrea-Silva J., Cosme F., Ribeiro L.F., Moreira A.S.P., Malheiro A.C., Coimbra M.A., Domingues M.R.M., Nunes F.M. (2014) Origin of the Pinking Phenomenon of White Wines. In: Journal Of Agricultural And Food Chemistry. 62, 24, 5651-5659.
Antunes D., Padrao A.I., Maciel E., Santinha D., Oliveira P., Vitorino R., Moreira-Goncalves D., Colaco B., Pires M.J., Nunes C., Santos L.L., Amado F., Duarte J.A., Domingues M.R., Ferreira R. (2014) Molecular insights into mitochondrial dysfunction in cancer-related muscle wasting. In: Biochimica Et Biophysica Acta-molecular And Cell Biology Of Lipids. 1841, 6, 896-905.
Lourenco L.M.O., Pereira P.M.R., Maciel E., Valega M., Domingues F.M.J., Domingues M.R.M., Neves M.G.P.M.S., Cavaleiro J.A.S., Fernandes R., Tome J.P.C. (2014) Amphiphilic phthalocyanine-cyclodextrin conjugates for cancer photodynamic therapy. In: Chemical Communications. 50, 61, 8363-8366.
Coelho C., Ribeiro M., Cruz A.C.S., Domingues M.R.M., Coimbra M.A., Bunzel M., Nunes F.M. (2014) Nature of Phenolic Compounds in Coffee Melanoidins. In: Journal Of Agricultural And Food Chemistry. 62, 31, 7843-7853.
Pinto J., Maciel E., Melo T.S., Domingues M.R.M., Galhano E., Pita C., Almeida M.D., Carreira I.M., Gil A.M. (2014) Maternal plasma phospholipids are altered in trisomy 21 cases and prior to preeclampsia and preterm outcomes. In: Rapid Communications In Mass Spectrometry. 28, 14, 1635-1638.
Faria R., Santana M.M., Aveleira C.A., Simoes C., Maciel E., Melo T., Santinha D., Oliveira M.M., Peixoto F., Domingues P., Cavadas C., Domingues M.R.M. (2014) ALTERATIONS IN PHOSPHOLIPIDOMIC PROFILE IN THE BRAIN OF MOUSE MODEL OF DEPRESSION INDUCED BY CHRONIC UNPREDICTABLE STRESS. In: Neuroscience. 273, 1-11.
Silva D.M., Nunes C., Pereira I., Moreira A.S.P., Domingues M.R.M., Coimbra M.A., Gama F.M. (2014) Structural analysis of dextrins and characterization of dextrin-based biomedical hydrogels. In: Carbohydrate Polymers. 114, 458-466.
Santinha D., Ferreira-Fernandes E., Melo T., Silva E.M.P., Maciel E., Fardilha M., Domingues P., Domingues M.R.M. (2014) Evaluation of the photooxidation of galactosyl- and lactosylceramide by electrospray ionization mass spectrometry. In: Rapid Communications In Mass Spectrometry. 28, 21, 2275-2284.
Moreira A.S.P., Simoes J., Pereira A.T., Passos C.P., Nunes F.M., Domingues M.R.M., Coimbra M.A. (2014) Transglycosylation reactions between galactomannans and arabinogalactans during dry thermal treatment. In: Carbohydrate Polymers. 112, 48-55.
Goncalves I.O., Maciel E., Passos E., Torrella J.R., Rizo D., Viscor G., Rocha-Rodrigues S., Santos-Alves E., Domingues M.R., Oliveira P.J., Ascensao A., Magalhaes J. (2014) Exercise alters liver mitochondria phospholipidomic profile and mitochondrial activity in non-alcoholic steatohepatitis. In: International Journal Of Biochemistry & Cell Biology. 54, 163-173.
Monteiro-Cardoso V.F., Oliveira M.M., Melo T., Domingues M.R.M., Moreira P.I., Ferreiro E., Peixoto F., Videira R.A. (2015) Cardiolipin Profile Changes are Associated to the Early Synaptic Mitochondrial Dysfunction in Alzheimer's Disease. In: Journal Of Alzheimers Disease. 43, 4, 1375-1392.
Pinto J., Barros A.S., Domingues M.R.M., Goodfellow B.J., Galhano E., Pita C., Almeida M.D., Carreira I.M., Gil A.M. (2015) Following Healthy Pregnancy by NMR Metabolomics of Plasma and Correlation to Urine. In: Journal Of Proteome Research. 14, 2, 1263-1274.
Tyurina Y.Y., Polimova A.M., Maciel E., Tyurin V.A., Kapralova V.I., Winnica D.E., Vikulina A.S., Domingues M.R.M., McCoy J., Sanders L.H., Bayir H., Greenamyre J.T., Kagan V.E. (2015) LC/MS analysis of cardiolipins in substantia nigra and plasma of rotenone-treated rats: Implication for mitochondrial dysfunction in Parkinson's disease. In: Free Radical Research. 49, 5, 681-691.
Martins J.D., Silva A., Ferreira I., Goncalo M., Custodio J.B.A., Lopes M.C., Domingues M.R.M., Neves B.M., Cruz M.T. (2016) Adenosine diphosphate involvement in THP-1 maturation triggered by the contact allergen 1-fluoro-2,4-dinitrobenzene. In: Toxicology Research. 5, 6, 1512-1521.
Campos A.M., Maciel E., Moreira A.S.P., Sousa B., Melo T., Domingues P., Curado L., Antunes B., Domingues M.R.M., Santos F. (2016) Lipidomics of Mesenchymal Stromal Cells: Understanding the Adaptation of Phospholipid Profile in Response to Pro-Inflammatory Cytokines. In: Journal Of Cellular Physiology. 231, 5, 1024-1032.
Silva E.M.P., Barros C.M.R.F., Santos C.M.M., Barros A.S., Domingues M.R.M., Silva A.M.S. (2016) Characterization of 2,3-diarylxanthones by electrospray mass spectrometry: gas-phase chemistry versus known antioxidant activity properties. In: Rapid Communications In Mass Spectrometry. 30, 20, 2228-2236.
Goncalves V.M.F., Reis A., Domingues M.R.M., Lopes-da-Silva J.A., Fialho A.M., Moreira L.M., Sa-Correia I., Coimbra M.A. (2009) Structural analysis of gellans produced by Sphingomonas elodea strains by electrospray tandem mass spectrometry. In: Carbohydrate Polymers. 77, 1, 10-19.
Moreira A.S.P., Coimbra M.A., Nunes F.M., Simoes J., Domingues M.R.M. (2011) Evaluation of the Effect of Roasting on the Structure of Coffee Galactomannans Using Model Oligosaccharides. In: Journal Of Agricultural And Food Chemistry. 59, 18, 10078-10087.
Simoes J., Moreira A.S.P., da Costa E., Evtyugin D., Domingues P., Nunes F.M., Coimbra M.A., Domingues R.M. (2016) Oxidation of amylose and amylopectin by hydroxyl radicals assessed by electrospray ionisation mass spectrometry. In: Carbohydrate Polymers. 148, 290-299.
Tyurina Y.Y., Domingues R.M., Tyurin V.A., Maciel E., Domingues P., Amoscato A.A., Bayir H., Kagan V.E. (2014) Characterization of cardiolipins and their oxidation products by LC-MS analysis. In: Chemistry And Physics Of Lipids. 179, 3-10.
Domingues R.M., Domingues P., Melo T., Perez-Sala D., Reis A., Spickett C.M. (2013) Lipoxidation adducts with peptides and proteins: Deleterious modifications or signaling mechanisms?. In: Journal Of Proteomics. 92, 110-131.
Domingues R.M., Domingues P., Melo T., Perez-Sala D., Reis A., Spickett C.M. (2013) Lipoxidation adducts with peptides and proteins: Deleterious modifications or signaling mechanisms?. In: Journal Of Proteomics. 92, 110-131.
Villaverde J.J., Oliveira L., Vilela C., Domingues R.M., Freitas N., Cordeiro N., Freire C.S.R., Silvestre A.J.D. (2013) High valuable compounds from the unripe peel of several Musa species cultivated in Madeira Island (Portugal). In: Industrial Crops And Products. 42, 507-512.
da Costa E., Azevedo V., Melo T., Rego A.M., Evtuguin D.V., Domingues P., Calado R., Pereira R., Abreu M.H., Domingues M.R. (2018) High-resolution lipidomics of the early life stages of the red seaweed Porphyra dioica. In: Molecules. 23, 1,
Alves E., Rey F., da Costa E., Moreira A.S.P., Pato L., Pato L., Domingues M.D.M., Domingues P. (2018) Olive (Olea europaea L. cv. Galega vulgar) Seed Oil: A First Insight into the Major Lipid Composition of a Promising Agro-Industrial By-Product at Two Ripeness Stages. In: European Journal Of Lipid Science And Technology. 120, 4,
Silva E.M.P., Varandas P.A.M.M., Melo T., Barros C., Alencastre I.S., Barreiros L., Domingues P., Lamghari M., Domingues M.R.M., Segundo M.A. (2018) Gas-phase structural characterization of neuropeptides Y Y1 receptor antagonists using mass spectrometry: Orbitrap vs triple quadrupole. In: Journal Of Pharmaceutical And Biomedical Analysis. 151, 227-234.
Rudnitskaya A., Schmidtke L.M., Reis A., Domingues M.R.M., Delgadillo I., Debus B., Kirsanov D., Legin A. (2017) Measurements of the effects of wine maceration with oak chips using an electronic tongue. In: Food Chemistry. 229, 20-27.
Rey F., da Costa E., Campos A.M., Cartaxana P., Maciel E., Domingues P., Domingues M.R.M., Calado R., Cruz S. (2017) Kleptoplasty does not promote major shifts in the lipidome of macroalgal chloroplasts sequestered by the sacoglossan sea slug Elysia viridis. In: Scientific Reports. 7,
Other Papers (2)
Eliana Alves,* Felisa Rey, Elisabete da Costa, Ana S. P. Moreira, Luísa Pato, Luís Pato, Maria do Rosário M. Domingues, and Pedro Domingues (2018) Olive (Olea europaea L. cv. Galega vulgar) Seed Oil: A First Insight into the Major Lipid Composition of a Promising Agro-Industrial By-Product at Two Ripeness Stages. In:
Gas-phase structural characterization of neuropeptides Y Y1 receptor antagonists using mass spectrometry: Orbitrap vs triple quadrupole. In:
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Communications (1)
Colombo S., Coliva G., Kraj A., Chervet J.P., Fedorova M., Domingues P., Domingues M.R. (2017) Oxidative metabolism of phosphatidylethanolamines predicted by electrochemistry-mass spectrometry. In: Free Radical Biology And Medicine. 108, S62-S62.
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CESAM - Centro de Estudos do Ambiente e do Mar - Universidade de Aveiro

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